NECAT Home Page

The Northeastern Collaborative Access Team (NE-CAT) facility at the Advanced Photon Source at Argonne National Laboratory is managed by Cornell University and consists of seven member institutions:

Columbia University

Cornell University

Harvard University

Memorial Sloan-Kettering Cancer Center

Massachusetts Institute of Technology

Rockefeller University

Yale University.

Primary funding for this project comes from the National Institute of General Medical Sciences(NIGMS) , a division of the National Institutes of Health (NIH). Additional financial support for NE-CAT comes from the member institutions.

NIGMS Fast Facts

Supported by:

National Institutes of Health
National Institue of General Medical Sciences

Recent Highlights

10/26/2012

Marcia, M., and Pyle, A.M. (2012)
Visualizing Group II Intron Catalysis through the Stages of Splicing, Cell151, 497-507.

Rea d the article.

09/19/2012

Baconguis, I., and Gouaux, E. (2012) Structural plasticity and dynamic selectivity of acid-sensing ion channel-spider toxin complexes, Nature 489, 400-405.

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06/21/2012

Nakanishi, K., Weinberg, D. E., Bartel, D. P., and Patel, D. J. (2012) Structure of yeast Argonaute with guide RNA, Nature 486, 368-374.

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05/25/2012

Sosa, B. A., Rothballer, A., Kutay, U., and Schwartz, T. U. (2012) LINC Complexes Form by Binding of Three KASH Peptides to Domain Interfaces of Trimeric SUN Proteins, Cell 149, 1035-1047.

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05/25/2012

Hattori, M., and Gouaux, E. (2012) Molecular mechanism of ATP binding and ion channel activation in P2X receptors, Nature 485, 207-212.

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05/18//2012

Polikanov, Y. S., Blaha, G. M., and Steitz, T. A. (2012) How hibernation factors RMF, HPF, and YfiA turn off protein synthesis, Science 336, 915-918.

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04/18/2012

Kung, Y., Ando, N., Doukov, T. I., Blasiak, L. C., Bender, G., Seravalli, J., Ragsdale, S. W., and Drennan, C. L. (2012) Visualizing molecular juggling within a B12-dependent methyltransferase complex, Nature 484, 265-269.

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03/19/2012

Laganowsky, A., Liu, C., Sawaya, M. R., Whitelegge, J. P., Park, J., Zhao, M., Pensalfini, A., Soriaga, A. B., Landau, M., Teng, P. K., Cascio, D., Glabe, C., and Eisenberg, D. (2012) Atomic view of a toxic amyloid small oligomer, Science 335, 1228-1231.

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01/27/2012

Brohawn, S. G., del Marmol, J., and MacKinnon, R. (2012) Crystal structure of the human K2P TRAAK, a lipid- and mechano-sensitive K+ ion channel, Science 335, 436-441.

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Comment: Poulsen, H., and Nissen, P. (2012) Structural biology. The inner workings of a dynamic duo, Science 335, 416-417.

11/11/2011

Scott, D. C., Monda, J. K., Bennett, E. J., Harper, J. W., and Schulman, B. A. (2011) N-Terminal Acetylation Acts as an Avidity Enhancer Within an Interconnected Multiprotein Complex, Science 334, 674-678.

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08/12/2011

Hu, J., Xue, Y., Lee, S., and Ha, Y. (2011) The crystal structure of GXGD membrane protease FlaK, Nature 475, 528-531

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Highlights in C&E News.