Status of NE-CAT Sector 24 ActivitiesJuly 2008
During this period we were presented first with some bad and then good news from APS. The 2008-2 run, was shortened by about three weeks due to an APS budget shortfall, and concluded on August 12. However, hearing that they would receive approximately $7M of supplemental funding for the remainder of FY2008, APS announced that the 2008-3 user operation would not be shortened as originally feared. Unfortunately, the APS operating schedule for users throughout 2009 still remains uncertain and subject to uncertainties of congressional action on DOE Office of Science’s 2009 budget request.
User Operations During the operational months in July and August, NE- CAT users of both insertion beamlines reported successful runs. Both beamlines operated reliably with no users losing any significant amount of beam time due to faults with the beamlines. However, APS experienced a number of failures in accelerator operations during this period most of short duration but one which was lengthy. On Saturday, August 16 APS experienced a 14 hour long accelerator fault. However, in spite of the problems experienced with the accelerator on this day, only one user group of NE- CAT’s beamlines, a group from the University of Chicago, was unable to complete its planned experiments. The following pie charts summarize scheduled usage of NE- CAT’s beamlines during the last run period, 2008-2. 24-ID-C Usage by Group
24-ID-E Usage by Group
Particularly notable, both beamlines were fully booked. General User usage of 24-ID-C continued to rise to 43% (47% when subtracting “Development” time resulting in the percentage of time actually available for scheduling of users) which is very close to our target of 50% for General Users. Usage of 24-ID-E by General Users has risen to 35% (39%), substantially above our target of 25% for the first year of operation of this beamline. For both beamlines, “Development Time” of ~10% was a little higher than normal during this period due to the need to train NE- CAT’s three new hires and to improve the reliability of the automated sample placement robot on 24-ID-C which was placed into user operation during this period.
Automated Sample Placement Robotic System During this period, eight research groups used the newly operational automated sample placement robotics system on the 24-ID-C beamline, mounting and dismounting some 500 crystals. All reported satisfactory results with only a relatively few problems in mounts and dismounts encountered for which the problems were quickly resolved during this commissioning phase. With this early successful experience and reliability of the robotic system steadily improving, an increasing number of users are requesting time to use the robot for screening of their crystals.
Status of New MD2 Microdiffractometer We have been informed by ACCEL that our second MD2 microdiffractometer, scheduled for installation on 24-ID-C, will most likely be shipped to us late in September, too late to be installed in time for the 2008-3 run beginning October 2. Therefore, installation of the new microdiffractometer on 24-ID-C is now scheduled for the December-January shutdown, with user operation beginning at the start of the 2009-1 run.
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Recent Highlights08/19/2008 July-August status report now available. 7/07/2008 June status report now online. 06/24/2008 NE-CAT Hires Three New User Support Staff (More Info)
06/12/2008 May status report is now available. 05/06/2008 NE-CAT organizes a successful workshop titled “Software for Challenging Cases in Macromolecular Crystallography” at APS User Week 2008. A photo of the organizers and speakers is shown. Presentations can be found here. 4/04/2008 Featured Publication Crystal Structure of a Self-Spliced Group ll Intron Navtej Toor, Kevin S. Keating, Sean D. Taylor, and Anna Marie Pyle Science 4 April 2008, Vol. 320. No. 5872, pp. 77-82 04/01/2008 With the success users have had using the MD2 Microdiffractometer on 24-ID-E, NE-CAT is acquiring a second MD2 for 24-ID-C, delivery October 2008 2/27/2008 NE-CAT hosting the workshop “WK04, Software for Challenging Cases in Macromolecular Crystallography” to be held May 6, 2008 at APS User Week. See the APS User Meeting Website 1/22/2008 Modified ALS sample placement robotic system installed on 24-ID-C beamline Resource Advisory Committee Meeting Held NE-CAT Director Steven Ealick Provides Introductory Overview 16x16x300 micron crystal irradiated at 5 different positions using a 20 micron beam with the MD2 microdiffractometer to obtain a complete data set with a radiation-damage sensitive crystal First Data Frames Obtained Using the MD2 Microdiffractometer (see additional pictures) MD2 Microdiffractometer Installed on 24-ID-E beamline 5/22/2006 Phase 2 Vertical Focusing Mirror in Place. |
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