In 2019 and 2020, the Kranzusch Lab of Harvard Medical School’s Dana Farber Cancer Institute observed the behavior of poxviruses in studies of a molecule (cGAMP) commonly produced by mammalian cells when they evade viral infection. The researchers had isolated a gene from a poxvirus that seemed designed to degrade that protective molecule and thus help the virus avoid signaling an immune response.  Monkeypox is a poxvirus and you can read the entire press release regarding the Kranzusch lab's work at NE-CAT at: https://www.anl.gov/article/scientists-follow-the-world-health-organizations-gaze-toward-monkeypox-virus