Publications
Found 72 results
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Epistatic mutations in PUMA BH3 drive an alternate binding mode to potently and selectively inhibit anti-apoptotic Bfl-1. Elife. 10.7554/eLife.25541
(2017) Structural insights into the binding of the human receptor for advanced glycation end products (RAGE) by S100B, as revealed by an S100B-RAGE-derived peptide complex. Acta Crystallogr D Biol Crystallogr. 71, 1176-83
(2015) Mechanistic Implications of the Unique Structural Features and Dimerization of the Cytoplasmic Domain of the Pseudomonas Sigma Regulator, PupR. Biochemistry. 54, 5867-77
(2015) Targeting the Spike Receptor Binding Domain Class V Cryptic Epitope by an Antibody with Pan-Sarbecovirus Activity. J Virol. 97, e0159622
(2023) Structural basis of cell surface signaling by a conserved sigma regulator in Gram-negative bacteria. J Biol Chem. 10.1074/jbc.RA119.010697
(2020) "The structure of the Type III secretion system export gate with CdsO, an ATPase lever arm". PLoS Pathog. 16, e1008923
(2020) Structure of the DASH/Dam1 complex shows its role at the yeast kinetochore-microtubule interface. Science. 360, 552-558
(2018) Structural Basis of Neurohormone Perception by the Receptor Tyrosine Kinase Torso. Mol Cell. 60, 941-52
(2015) Mutagenesis studies on TenA: a thiamin salvage enzyme from Bacillus subtilis. Bioorg Chem. 36, 29-32
(2008) Extension of the Notch intracellular domain ankyrin repeat stack by NRARP promotes feedback inhibition of Notch signaling. Sci Signal. 10.1126/scisignal.aay2369
(2019) (2011) Discovery of a Highly Potent and Broadly Effective Epidermal Growth Factor Receptor and HER2 Exon 20 Insertion Mutant Inhibitor. Angew Chem Int Ed Engl. 57, 11629-11633
(2018) (2014) (2016) Mechanism of error-free DNA synthesis across N1-methyl-deoxyadenosine by human DNA polymerase-ι.. Sci Rep. 7, 43904
(2017) Zooming in on Cadherin-23: Structural Diversity and Potential Mechanisms of Inherited Deafness. Structure. 10.1016/j.str.2018.06.003
(2018) Structural and computational studies of the Staphylococcus aureus sortase B-substrate complex reveal a substrate-stabilized oxyanion hole. J Biol Chem. 289, 8891-902
(2014) X-Ray Structure of Human Sulfide:Quinone Oxidoreductase: Insights into the Mechanism of Mitochondrial Hydrogen Sulfide Oxidation. Structure. 10.1016/j.str.2019.03.002
(2019) Structural basis for Tpt1-catalyzed 2'-PO transfer from RNA and NADP(H) to NAD. Proc Natl Acad Sci U S A. 120, e2312999120
(2023) Crystal structure, mutational analysis and RNA-dependent ATPase activity of the yeast DEAD-box pre-mRNA splicing factor Prp28. Nucleic Acids Res. 42, 12885-98
(2014) Structures of RNA ligase RtcB in complexes with divalent cations and GTP. RNA. 10.1261/rna.079327.122
(2022) An antibiotic preorganized for ribosomal binding overcomes antimicrobial resistance. Science. 383, 721-726
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