Publications
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Human cGAS catalytic domain has an additional DNA-binding interface that enhances enzymatic activity and liquid-phase condensation. Proc Natl Acad Sci U S A. 116, 11946-11955
(2019) (2011) Impaired dNTPase activity of SAMHD1 by phosphomimetic mutation of Thr-592. J Biol Chem. 290, 26352-9
(2015) Insights into Autoregulation of Notch3 from Structural and Functional Studies of Its Negative Regulatory Region. Structure. 23, 1227-35
(2015) Insights into base selectivity from the 1.8 Å resolution structure of an RB69 DNA polymerase ternary complex.. Biochemistry. 50, 581-90
(2011) Insights into DNA substrate selection by APOBEC3G from structural, biochemical, and functional studies. PLoS One. 13, e0195048
(2018) Insights into Eph receptor tyrosine kinase activation from crystal structures of the EphA4 ectodomain and its complex with ephrin-A5. Proc Natl Acad Sci U S A. 110, 14634-9
(2013) Insights into Eph receptor tyrosine kinase activation from crystal structures of the EphA4 ectodomain and its complex with ephrin-A5. Proc Natl Acad Sci U S A. 110, 14634-9
(2013) (2019) K29-linked ubiquitin signaling regulates proteotoxic stress response and cell cycle. Nat Chem Biol. 17, 896-905
(2021) (2021) (2013)
Lysophospholipases cooperate to mediate lipid homeostasis and lysophospholipid signaling. J Lipid Res. 60, 360-374
(2019) Mechanically rigid supramolecular assemblies formed from an Fmoc-guanine conjugated peptide nucleic acid. Nat Commun. 10, 5256
(2019) (2013) Mechanism of differential Zika and dengue virus neutralization by a public antibody lineage targeting the DIII lateral ridge. J Exp Med. 10.1084/jem.20191792
(2020) Mechanism of Error-Free DNA Replication Past Lucidin-Derived DNA Damage by Human DNA Polymerase κ.. Chem Res Toxicol. 10.1021/acs.chemrestox.7b00227
(2017) Mechanism of Error-Free DNA Replication Past Lucidin-Derived DNA Damage by Human DNA Polymerase κ.. Chem Res Toxicol. 10.1021/acs.chemrestox.7b00227
(2017) Mechanism of transfer RNA maturation by CCA-adding enzyme without using an oligonucleotide template. Nature. 430, 640-5
(2004) Mechanisms of substrate recognition by a typhoid toxin secretion-associated muramidase. Elife. 10.7554/eLife.53473
(2020) (2014) The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes. Nat Commun. 5, 2987
(2014) Mispairs with Watson-Crick base-pair geometry observed in ternary complexes of an RB69 DNA polymerase variant. Protein Sci. 23, 508-13
(2014) MOB1 Mediated Phospho-recognition in the Core Mammalian Hippo Pathway. Mol Cell Proteomics. 16, 1098-1110
(2017) Modular HIV-1 Capsid Assemblies Reveal Diverse Host-Capsid Recognition Mechanisms. Cell Host Microbe. 26, 203-216.e6
(2019)