Found 13 results
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Journal Article
Silvaroli, J. A., Widjaja-Adhi, M. Airanthi K., Trischman, T., Chelstowska, S., Horwitz, S., Banerjee, S., Kiser, P. D., Blaner, W. S., and Golczak, M. (2019) Abnormal Cannabidiol Modulates Vitamin A Metabolism by Acting as a Competitive Inhibitor of CRBP1. ACS Chem Biol. 10.1021/acschembio.8b01070
Sui, X., Kiser, P. D., Che, T., Carey, P. R., Golczak, M., Shi, W., von Lintig, J., and Palczewski, K. (2014) Analysis of carotenoid isomerase activity in a prototypical carotenoid cleavage enzyme, apocarotenoid oxygenase (ACO). J Biol Chem. 289, 12286-99
Kiser, P. D., Zhang, J., Badiee, M., Li, Q., Shi, W., Sui, X., Golczak, M., Tochtrop, G. P., and Palczewski, K. (2015) Catalytic mechanism of a retinoid isomerase essential for vertebrate vision. Nat Chem Biol. 11, 409-15
Silvaroli, J. A., Pleshinger, M. J., Banerjee, S., Kiser, P. D., and Golczak, M. (2017) Enzyme That Makes You Cry-Crystal Structure of Lachrymatory Factor Synthase from Allium cepa. ACS Chem Biol. 10.1021/acschembio.7b00336
Sui, X., Zhang, J., Golczak, M., Palczewski, K., and Kiser, P. D. (2016) Key Residues for Catalytic Function and Metal Coordination in a Carotenoid Cleavage Dioxygenase. J Biol Chem. 291, 19401-12
Silvaroli, J. A., Arne, J. M., Chelstowska, S., Kiser, P. D., Banerjee, S., and Golczak, M. (2016) Ligand Binding Induces Conformational Changes in Human Cellular Retinol-binding Protein 1 (CRBP1) Revealed by Atomic Resolution Crystal Structures. J Biol Chem. 291, 8528-40
Golczak, M., Sears, A. E., Kiser, P. D., and Palczewski, K. (2015) LRAT-specific domain facilitates vitamin A metabolism by domain swapping in HRASLS3. Nat Chem Biol. 11, 26-32
Widjaja-Adhi, M. Airanthi K., and Golczak, M. (2020) The molecular aspects of absorption and metabolism of carotenoids and retinoids in vertebrates. Biochim Biophys Acta Mol Cell Biol Lipids. 1865, 158571
Silvaroli, J. A., Plau, J., Adams, C. H., Banerjee, S., Widjaja-Adhi, M. Airanthi K., Blaner, W. S., and Golczak, M. (2021) Molecular basis for the interaction of cellular retinol-binding protein 2 (CRBP2) with non-retinoid ligands. J Lipid Res. 10.1016/j.jlr.2021.100054
Zhang, J., Kiser, P. D., Badiee, M., Palczewska, G., Dong, Z., Golczak, M., Tochtrop, G. P., and Palczewski, K. (2015) Molecular pharmacodynamics of emixustat in protection against retinal degeneration. J Clin Invest. 125, 2781-94
Lee, S. - A., Yang, K. Jian Zhang, Brun, P. - J., Silvaroli, J. A., Yuen, J. J., Shmarakov, I., Jiang, H., Feranil, J. B., Li, X., Lackey, A. I., Krężel, W., Leibel, R. L., Libien, J., Storch, J., Golczak, M., and Blaner, W. S. (2020) Retinol-binding protein 2 (RBP2) binds monoacylglycerols and modulates gut endocrine signaling and body weight. Sci Adv. 6, eaay8937
Golczak, M., Kiser, P. D., Sears, A. E., Lodowski, D. T., Blaner, W. S., and Palczewski, K. (2012) Structural basis for the acyltransferase activity of lecithin:retinol acyltransferase-like proteins. J Biol Chem. 287, 23790-807
Sui, X., Golczak, M., Zhang, J., Kleinberg, K. A., von Lintig, J., Palczewski, K., and Kiser, P. D. (2015) Utilization of Dioxygen by Carotenoid Cleavage Oxygenases. J Biol Chem. 290, 30212-23