Publications

Found 29 results
Filters: Author is Yu, Edward W  [Clear All Filters]
Journal Article
Su, C. - C., Long, F., Lei, H. - T., Bolla, J. Reddy, Do, S. V., Rajashankar, K. R., and Yu, E. W. (2012) Charged amino acids (R83, E567, D617, E625, R669, and K678) of CusA are required for metal ion transport in the Cus efflux system. J Mol Biol. 422, 429-41
Gu, R., Li, M., Su, C. Chia, Long, F., Routh, M. D., Yang, F., McDermott, G., and Yu, E. W. (2008) Conformational change of the AcrR regulator reveals a possible mechanism of induction. Acta Crystallogr Sect F Struct Biol Cryst Commun. 64, 584-8
Kumar, N., Radhakrishnan, A., Su, C. - C., Osteryoung, K. W., and Yu, E. W. (2016) Crystal structure of a conserved domain in the intermembrane space region of the plastid division protein ARC6. Protein Sci. 25, 523-9
Bolla, J. Reddy, Su, C. - C., Delmar, J. A., Radhakrishnan, A., Kumar, N., Chou, T. - H., Long, F., Rajashankar, K. R., and Yu, E. W. (2015) Crystal structure of the Alcanivorax borkumensis YdaH transporter reveals an unusual topology. Nat Commun. 6, 6874
Su, C. - C., Radhakrishnan, A., Kumar, N., Long, F., Bolla, J. Reddy, Lei, H. - T., Delmar, J. A., Do, S. V., Chou, T. - H., Rajashankar, K. R., Zhang, Q., and Yu, E. W. (2014) Crystal structure of the Campylobacter jejuni CmeC outer membrane channel. Protein Sci. 23, 954-61
Su, C. - C., Long, F., Zimmermann, M. T., Rajashankar, K. R., Jernigan, R. L., and Yu, E. W. (2011) Crystal structure of the CusBA heavy-metal efflux complex of Escherichia coli. Nature. 470, 558-62
Su, C. - C., Yang, F., Long, F., Reyon, D., Routh, M. D., Kuo, D. W., Mokhtari, A. K., Van Ornam, J. D., Rabe, K. L., Hoy, J. A., Lee, Y. Jin, Rajashankar, K. R., and Yu, E. W. (2009) Crystal structure of the membrane fusion protein CusB from Escherichia coli. J Mol Biol. 393, 342-55
Chou, T. - H., Delmar, J. A., Wright, C. C., Kumar, N., Radhakrishnan, A., Doh, J. K., Licon, M. H., Bolla, J. Reddy, Lei, H. - T., Rajashankar, K. R., Su, C. - C., Purdy, G. E., and Yu, E. W. (2015) Crystal structure of the Mycobacterium tuberculosis transcriptional regulator Rv0302. Protein Sci. 24, 1942-55
Bolla, J. Reddy, Su, C. - C., Do, S. V., Radhakrishnan, A., Kumar, N., Long, F., Chou, T. - H., Delmar, J. A., Lei, H. - T., Rajashankar, K. R., Shafer, W. M., and Yu, E. W. (2014) Crystal structure of the Neisseria gonorrhoeae MtrD inner membrane multidrug efflux pump. PLoS One. 9, e97903
Lei, H. - T., Chou, T. - H., Su, C. - C., Bolla, J. Reddy, Kumar, N., Radhakrishnan, A., Long, F., Delmar, J. A., Do, S. V., Rajashankar, K. R., Shafer, W. M., and Yu, E. W. (2014) Crystal structure of the open state of the Neisseria gonorrhoeae MtrE outer membrane channel. PLoS One. 9, e97475
Radhakrishnan, A., Kumar, N., Wright, C. C., Chou, T. - H., Tringides, M. L., Bolla, J. Reddy, Lei, H. - T., Rajashankar, K. R., Su, C. - C., Purdy, G. E., and Yu, E. W. (2014) Crystal structure of the transcriptional regulator Rv0678 of Mycobacterium tuberculosis. J Biol Chem. 289, 16526-40
Kumar, N., Radhakrishnan, A., Wright, C. C., Chou, T. - H., Lei, H. - T., Bolla, J. Reddy, Tringides, M. L., Rajashankar, K. R., Su, C. - C., Purdy, G. E., and Yu, E. W. (2014) Crystal structure of the transcriptional regulator Rv1219c of Mycobacterium tuberculosis. Protein Sci. 23, 423-32
Lei, H. - T., Shen, Z., Surana, P., Routh, M. D., Su, C. - C., Zhang, Q., and Yu, E. W. (2011) Crystal structures of CmeR-bile acid complexes from Campylobacter jejuni. Protein Sci. 20, 712-23
Lei, H. - T., Bolla, J. Reddy, Bishop, N. R., Su, C. - C., and Yu, E. W. (2014) Crystal structures of CusC review conformational changes accompanying folding and transmembrane channel formation. J Mol Biol. 426, 403-11
Kumar, N., Su, C. - C., Chou, T. - H., Radhakrishnan, A., Delmar, J. A., Rajashankar, K. R., and Yu, E. W. (2017) Crystal structures of the Burkholderia multivorans hopanoid transporter HpnN. Proc Natl Acad Sci U S A. 114, 6557-6562
Long, F., Su, C. - C., Zimmermann, M. T., Boyken, S. E., Rajashankar, K. R., Jernigan, R. L., and Yu, E. W. (2010) Crystal structures of the CusA efflux pump suggest methionine-mediated metal transport. Nature. 467, 484-8
Su, C. - C., Long, F., McDermott, G., Shafer, W. M., and Yu, E. W. (2008) Crystallization and preliminary X-ray diffraction analysis of the multidrug efflux transporter NorM from Neisseria gonorrhoeae. Acta Crystallogr Sect F Struct Biol Cryst Commun. 64, 289-92
Delmar, J. A., and Yu, E. W. (2018) Crystallographic Analysis of the CusBA Heavy-Metal Efflux Complex of Escherichia coli. Methods Mol Biol. 1700, 59-70
Su, C. - C., Long, F., and Yu, E. W. (2011) The Cus efflux system removes toxic ions via a methionine shuttle. Protein Sci. 20, 6-18
Plau, J., Morgan, C. E., Fedorov, Y., Banerjee, S., Adams, D. J., Blaner, W. S., Yu, E. W., and Golczak, M. (2023) Discovery of Nonretinoid Inhibitors of CRBP1: Structural and Dynamic Insights for Ligand-Binding Mechanisms. ACS Chem Biol. 18, 2309-2323
Su, C. - C., Klenotic, P. A., Bolla, J. Reddy, Purdy, G. E., Robinson, C. V., and Yu, E. W. (2019) MmpL3 is a lipid transporter that binds trehalose monomycolate and phosphatidylethanolamine. Proc Natl Acad Sci U S A. 10.1073/pnas.1901346116
Bolla, J. Reddy, Do, S. V., Long, F., Dai, L., Su, C. - C., Lei, H. - T., Chen, X., Gerkey, J. E., Murphy, D. C., Rajashankar, K. R., Zhang, Q., and Yu, E. W. (2012) Structural and functional analysis of the transcriptional regulator Rv3066 of Mycobacterium tuberculosis. Nucleic Acids Res. 40, 9340-55
Melly, G. C., Stokas, H., Dunaj, J. L., Hsu, F. - F., Rajavel, M., Su, C. - C., Yu, E. W., and Purdy, G. E. (2019) Structural and functional evidence that lipoprotein LpqN supports cell envelope biogenesis in . J Biol Chem. 10.1074/jbc.RA119.008781
Delmar, J. A., Chou, T. - H., Wright, C. C., Licon, M. H., Doh, J. K., Radhakrishnan, A., Kumar, N., Lei, H. - T., Bolla, J. Reddy, Rajashankar, K. R., Su, C. - C., Purdy, G. E., and Yu, E. W. (2015) Structural Basis for the Regulation of the MmpL Transporters of Mycobacterium tuberculosis. J Biol Chem. 290, 28559-74
Zhang, Z., Yan, Y., Pang, J., Dai, L., Zhang, Q., and Yu, E. W. (2024) Structural basis of DNA recognition of the CosR regulator. mBio. 15, e0343023

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