Publications
Found 72 results
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Evaluating the therapeutic potential of a non-natural nucleotide that inhibits human ribonucleotide reductase. Mol Cancer Ther. 11, 2077-86
(2012) (2016) (2018) EGF-receptor specificity for phosphotyrosine-primed substrates provides signal integration with Src. Nat Struct Mol Biol. 22, 983-90
(2015) Engineered Antigen-Binding Fragments for Enhanced Crystallization of Antibody:Antigen Complexes. Protein Sci. 10.1002/pro.4824
(2023) (2012) Expanded use of sense codons is regulated by modified cytidines in tRNA. Proc Natl Acad Sci U S A. 110, 10964-9
(2013) Epstein-Barr virus gH/gL has multiple sites of vulnerability for virus neutralization and fusion inhibition. Immunity. 55, 2135-2148.e6
(2022) (2012) Elucidation of the Covalent and Tertiary Structures of Biologically Active Ts3 Toxin. Angew Chem Int Ed Engl. 55, 8639-42
(2016) Efficient Total Chemical Synthesis of (13) C=(18) O Isotopomers of Human Insulin for Isotope-Edited FTIR. Chembiochem. 17, 415-20
(2016) Effector-mediated membrane disruption controls cell death in CBASS antiphage defense. Mol Cell. 10.1016/j.molcel.2021.10.020
(2021) (2016)
Effect of Mutation and Substrate Binding on the Stability of Cytochrome P450BM3 Variants. Biochemistry. 55, 3594-606
(2016) (2018) (2009) Exploring novel HIV-1 reverse transcriptase inhibitors with drug-resistant mutants: A double mutant surprise. Protein Sci. 32, e4814
(2023) An examination of the metal ion content in the active sites of human endonucleases CPSF73 and INTS11. J Biol Chem. 299, 103047
(2023) E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin. Nat Chem Biol. 10, 156-163
(2014) E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification. Mol Cell. 33, 483-95
(2009) Extension of the Notch intracellular domain ankyrin repeat stack by NRARP promotes feedback inhibition of Notch signaling. Sci Signal. 10.1126/scisignal.aay2369
(2019) Epistatic mutations in PUMA BH3 drive an alternate binding mode to potently and selectively inhibit anti-apoptotic Bfl-1. Elife. 10.7554/eLife.25541
(2017) Evaluating the Advantages of Using 3D-Enriched Fragments for Targeting BET Bromodomains. ACS Med Chem Lett. 10, 1648-1654
(2019) Exploring local solvation environments of a heme protein using the spectroscopic reporter 4-cyano-l-phenylalanine. RSC Adv. 8, 13503-13512
(2018) Exploration of Monosaccharide Inhibitors for Trypanosoma cruzi Glucokinase and Hexokinase. 66th Southeastern Regional Meeting of the American Chemical Society, October 16-19, 2015
(2015)