Publications

Found 458 results
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2012
Cheng, P. - N., Liu, C., Zhao, M., Eisenberg, D., and Nowick, J. S. (2012) Amyloid β-sheet mimics that antagonize protein aggregation and reduce amyloid toxicity.. Nat Chem. 4, 927-33
Nam, K. Hyun, Haitjema, C., Liu, X., Ding, F., Wang, H., DeLisa, M. P., and Ke, A. (2012) Cas5d protein processes pre-crRNA and assembles into a cascade-like interference complex in subtype I-C/Dvulg CRISPR-Cas system. Structure. 20, 1574-84
Gilbert, N. C., Rui, Z., Neau, D. B., Waight, M. T., Bartlett, S. G., Boeglin, W. E., Brash, A. R., and Newcomer, M. E. (2012) Conversion of human 5-lipoxygenase to a 15-lipoxygenase by a point mutation to mimic phosphorylation at Serine-663. FASEB J. 26, 3222-9
Gilbert, N. C., Rui, Z., Neau, D. B., Waight, M. T., Bartlett, S. G., Boeglin, W. E., Brash, A. R., and Newcomer, M. E. (2012) Conversion of human 5-lipoxygenase to a 15-lipoxygenase by a point mutation to mimic phosphorylation at Serine-663. FASEB J. 26, 3222-9
Dhatwalia, R., Singh, H., Oppenheimer, M., Karr, D. B., Nix, J. C., Sobrado, P., and Tanner, J. J. (2012) Crystal structures and small-angle x-ray scattering analysis of UDP-galactopyranose mutase from the pathogenic fungus Aspergillus fumigatus. J Biol Chem. 287, 9041-51
Crenshaw, C. M., Nam, K., Oo, K., Kutchukian, P. S., Bowman, B. R., Karplus, M., and Verdine, G. L. (2012) Enforced presentation of an extrahelical guanine to the lesion recognition pocket of human 8-oxoguanine glycosylase, hOGG1. J Biol Chem. 287, 24916-28
Krauthammer, M., Kong, Y., Ha, B. Hak, Evans, P., Bacchiocchi, A., McCusker, J. P., Cheng, E., Davis, M. J., Goh, G., Choi, M., Ariyan, S., Narayan, D., Dutton-Regester, K., Capatana, A., Holman, E. C., Bosenberg, M., Sznol, M., Kluger, H. M., Brash, D. E., Stern, D. F., Materin, M. A., Lo, R. S., Mane, S., Ma, S., Kidd, K. K., Hayward, N. K., Lifton, R. P., Schlessinger, J., Boggon, T. J., and Halaban, R. (2012) Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma. Nat Genet. 44, 1006-14
Cavalier, M. C., Yim, Y. - S., Asamizu, S., Neau, D., Almabruk, K. H., Mahmud, T., and Lee, Y. - H. (2012) Mechanistic insights into validoxylamine A 7'-phosphate synthesis by VldE using the structure of the entire product complex. PLoS One. 7, e44934
Cavalier, M. C., Kim, S. - G., Neau, D., and Lee, Y. - H. (2012) Molecular basis of the fructose-2,6-bisphosphatase reaction of PFKFB3: transition state and the C-terminal function. Proteins. 80, 1143-53
Xu, K., Chan, Y. - P., Rajashankar, K. R., Khetawat, D., Yan, L., Kolev, M. V., Broder, C. C., and Nikolov, D. B. (2012) New insights into the Hendra virus attachment and entry process from structures of the virus G glycoprotein and its complex with Ephrin-B2. PLoS One. 7, e48742
Liu, C., Zhao, M., Jiang, L., Cheng, P. - N., Park, J., Sawaya, M. R., Pensalfini, A., Gou, D., Berk, A. J., Glabe, C. G., Nowick, J., and Eisenberg, D. (2012) Out-of-register β-sheets suggest a pathway to toxic amyloid aggregates.. Proc Natl Acad Sci U S A. 109, 20913-8
Qi, Y., Nam, K., Spong, M. C., Banerjee, A., Sung, R. - J., Zhang, M., Karplus, M., and Verdine, G. L. (2012) Strandwise translocation of a DNA glycosylase on undamaged DNA. Proc Natl Acad Sci U S A. 109, 1086-91
Englert, M., Xia, S., Okada, C., Nakamura, A., Tanavde, V., Yao, M., Eom, S. Hyun, Konigsberg, W. H., Söll, D., and Wang, J. (2012) Structural and mechanistic insights into guanylylation of RNA-splicing ligase RtcB joining RNA between 3'-terminal phosphate and 5'-OH. Proc Natl Acad Sci U S A. 109, 15235-40
Yang, H., Ji, X., Zhao, G., Ning, J., Zhao, Q., Aiken, C., Gronenborn, A. M., Zhang, P., and Xiong, Y. (2012) Structural insight into HIV-1 capsid recognition by rhesus TRIM5α.. Proc Natl Acad Sci U S A. 109, 18372-7
Eek, P., Järving, R., Järving, I., Gilbert, N. C., Newcomer, M. E., and Samel, N. (2012) Structure of a calcium-dependent 11R-lipoxygenase suggests a mechanism for Ca2+ regulation. J Biol Chem. 287, 22377-86
Nakanishi, K., Weinberg, D. E., Bartel, D. P., and Patel, D. J. (2012) Structure of yeast Argonaute with guide RNA. Nature. 486, 368-74
Martin, R., Gupta, K., Ninan, N. S., Perry, K., and Van Duyne, G. D. (2012) The survival motor neuron protein forms soluble glycine zipper oligomers. Structure. 20, 1929-39
2011
Ni, S., McGookey, M. E., Tinch, S. L., Jones, A. N., Jayaraman, S., Tong, L., and Kennedy, M. A. (2011) The 1.7 Å resolution structure of At2g44920, a pentapeptide-repeat protein in the thylakoid lumen of Arabidopsis thaliana.. Acta Crystallogr Sect F Struct Biol Cryst Commun. 67, 1480-4
Ceccarelli, D. F., Tang, X., Pelletier, B., Orlicky, S., Xie, W., Plantevin, V., Neculai, D., Chou, Y. - C., Ogunjimi, A., Al-Hakim, A., Varelas, X., Koszela, J., Wasney, G. A., Vedadi, M., Dhe-Paganon, S., Cox, S., Xu, S., Lopez-Girona, A., Mercurio, F., Wrana, J., Durocher, D., Meloche, S., Webb, D. R., Tyers, M., and Sicheri, F. (2011) An allosteric inhibitor of the human Cdc34 ubiquitin-conjugating enzyme. Cell. 145, 1075-87
Taherbhoy, A. M., Tait, S. W., Kaiser, S. E., Williams, A. H., Deng, A., Nourse, A., Hammel, M., Kurinov, I., Rock, C. O., Green, D. R., and Schulman, B. A. (2011) Atg8 transfer from Atg7 to Atg3: a distinctive E1-E2 architecture and mechanism in the autophagy pathway. Mol Cell. 44, 451-61
Liu, C., Sawaya, M. R., Cheng, P. - N., Zheng, J., Nowick, J. S., and Eisenberg, D. (2011) Characteristics of amyloid-related oligomers revealed by crystal structures of macrocyclic β-sheet mimics.. J Am Chem Soc. 133, 6736-44
French, J. B., Neau, D. B., and Ealick, S. E. (2011) Characterization of the structure and function of Klebsiella pneumoniae allantoin racemase. J Mol Biol. 410, 447-60
Nam, K. Hyun, Kurinov, I., and Ke, A. (2011) Crystal structure of clustered regularly interspaced short palindromic repeats (CRISPR)-associated Csn2 protein revealed Ca2+-dependent double-stranded DNA binding activity. J Biol Chem. 286, 30759-68
Xu, G., Lo, Y. - C., Li, Q., Napolitano, G., Wu, X., Jiang, X., Dreano, M., Karin, M., and Wu, H. (2011) Crystal structure of inhibitor of κB kinase β.. Nature. 472, 325-30

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