Publications

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Zhao, C., and Pyle, A. Marie (2016) Crystal structures of a group II intron maturase reveal a missing link in spliceosome evolution. Nat Struct Mol Biol. 23, 558-65
Zhao, Q., Saro, D., Sachpatzidis, A., Singh, T. Ramsing, Schlingman, D., Zheng, X. - F., Mack, A., Tsai, M. - S., Mochrie, S., Regan, L., Meetei, A. Ruhikanta, Sung, P., and Xiong, Y. (2014) The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes. Nat Commun. 5, 2987
Zhao, Z., Zhou, M., Zemerov, S. D., Marmorstein, R., and Dmochowski, I. J. (2023) Rational design of a genetically encoded NMR zinc sensor. Chem Sci. 14, 3809-3815
Zhao, M., Cascio, D., Sawaya, M. R., and Eisenberg, D. (2011) Structures of segments of α-synuclein fused to maltose-binding protein suggest intermediate states during amyloid formation.. Protein Sci. 20, 996-1004
Zhao, S., Lu, J., Pan, B., Fan, H., Byrum, S. D., Xu, C., Kim, A., Guo, Y., Kanchi, K. L., Gong, W., Sun, T., Storey, A. J., Burkholder, N. T., Mackintosh, S. G., Kuhlers, P. C., Edmondson, R. D., Strahl, B. D., Diao, Y., Tackett, A. J., Raab, J. R., Cai, L., Song, J., and Wang, G. Greg (2023) TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons. Nature. 623, 633-642
Zhao, J., C Cochrane, S., Najeeb, J., Gooden, D., Sciandra, C., Fan, P., Lemaitre, N., Newns, K., Nicholas, R. A., Guan, Z., Thaden, J. T., Fowler, V. G., Spasojevic, I., Sebbane, F., Toone, E. J., Duncan, C., Gammans, R., and Zhou, P. (2023) Preclinical safety and efficacy characterization of an LpxC inhibitor against Gram-negative pathogens. Sci Transl Med. 15, eadf5668
Zhao, Q., Han, Q., Kissinger, C. R., Hermann, T., and Thompson, P. A. (2008) Structure of hepatitis C virus IRES subdomain IIa. Acta Crystallogr D Biol Crystallogr. 64, 436-43
Zhao, C., and Pyle, A. Marie (2017) The group II intron maturase: a reverse transcriptase and splicing factor go hand in hand. Curr Opin Struct Biol. 47, 30-39
Zhao, H., Xu, L., Bombardi, R., Nargi, R., Deng, Z., Errico, J. M., Nelson, C. A., Dowd, K. A., Pierson, T. C., Crowe, J. E., Diamond, M. S., and Fremont, D. H. (2020) Mechanism of differential Zika and dengue virus neutralization by a public antibody lineage targeting the DIII lateral ridge. J Exp Med. 10.1084/jem.20191792
Zhao, C., and Pyle, A. Marie (2017) Structural Insights into the Mechanism of Group II Intron Splicing. Trends Biochem Sci. 42, 470-482
Zhang, J., and Ferré-D'Amaré, A. R. (2015) Post-crystallization Improvement of RNA Crystal Diffraction Quality. Methods Mol Biol. 1316, 13-24
Zhang, Y., Cottet, S. E., and Ealick, S. E. (2004) Structure of Escherichia coli AMP nucleosidase reveals similarity to nucleoside phosphorylases. Structure. 12, 1383-94
Zhang, C. - H., Spasov, K. A., Reilly, R. A., Hollander, K., Stone, E. A., Ippolito, J. A., Liosi, M. - E., Deshmukh, M. G., Tirado-Rives, J., Zhang, S., Liang, Z., Miller, S. J., Isaacs, F., Lindenbach, B. D., Anderson, K. S., and Jorgensen, W. L. (2021) Optimization of Triarylpyridinone Inhibitors of the Main Protease of SARS-CoV-2 to Low-Nanomolar Antiviral Potency. ACS Med Chem Lett. 12, 1325-1332
Zhang, H., Astrof, N. S., Liu, J. -huan, Wang, J. -huai, and Shimaoka, M. (2009) Crystal structure of isoflurane bound to integrin LFA-1 supports a unified mechanism of volatile anesthetic action in the immune and central nervous systems. FASEB J. 23, 2735-40
Zhang, Z. - M., Rothbart, S. B., Allison, D. F., Cai, Q., Harrison, J. S., Li, L., Wang, Y., Strahl, B. D., Wang, G. Greg, and Song, J. (2015) An Allosteric Interaction Links USP7 to Deubiquitination and Chromatin Targeting of UHRF1. Cell Rep. 12, 1400-6
Zhang, X., Eser, B. E., Chanani, P. K., Begley, T. P., and Ealick, S. E. (2016) Structural Basis for Iron-Mediated Sulfur Transfer in Archael and Yeast Thiazole Synthases. Biochemistry. 55, 1826-38
Zhang, Y., Secrist, J. A., and Ealick, S. E. (2006) The structure of human deoxycytidine kinase in complex with clofarabine reveals key interactions for prodrug activation. Acta Crystallogr D Biol Crystallogr. 62, 133-9
Zhang, Y., Shan, C. - M., Wang, J., Bao, K., Tong, L., and Jia, S. (2017) Molecular basis for the role of oncogenic histone mutations in modulating H3K36 methylation. Sci Rep. 7, 43906
Zhang, Y., Dougherty, M., Downs, D. M., and Ealick, S. E. (2004) Crystal structure of an aminoimidazole riboside kinase from Salmonella enterica: implications for the evolution of the ribokinase superfamily. Structure. 12, 1809-21
Zhang, W., Shi, K., Geng, Q., Herbst, M., Wang, M., Huang, L., Bu, F., Liu, B., Aihara, H., and Li, F. (2023) Structural evolution of SARS-CoV-2 omicron in human receptor recognition. J Virol. 97, e0082223
Zhang, J., Huang, J., Xu, K., Xing, P., Huang, Y., Liu, Z., Tong, L., and Manley, J. L. (2022) DHX15 is involved in SUGP1-mediated RNA missplicing by mutant SF3B1 in cancer. Proc Natl Acad Sci U S A. 119, e2216712119
Zhang, Y., Kittredge, A., Ward, N., Ji, C., Chen, S., and Yang, T. (2018) ATP activates bestrophin ion channels through direct interaction. Nat Commun. 9, 3126
Zhang, Z., Liu, Q., and Hendrickson, W. A. (2014) Crystal structures of apparent saccharide sensors from histidine kinase receptors prevalent in a human gut symbiont. FEBS J. 281, 4263-79
Zhang, R., Li, X., and Boggon, T. J. (2015) Structural analysis of the KRIT1 ankyrin repeat and FERM domains reveals a conformationally stable ARD-FERM interface. J Struct Biol. 192, 449-56
Zhang, H., Pan, Y., Hu, L., M Hudson, A., Hofstetter, K. S., Xu, Z., Rong, M., Wang, Z., Prasad, B. V. Venkatar, Lockless, S. W., Chiu, W., and Zhou, M. (2020) TrkA undergoes a tetramer-to-dimer conversion to open TrkH which enables changes in membrane potential. Nat Commun. 11, 547

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