Publications
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(2013)
Structural mechanism of ligand activation in human calcium-sensing receptor. Elife. 10.7554/eLife.13662
(2016) Structure of mouse protocadherin 15 of the stereocilia tip link in complex with LHFPL5. Elife. 10.7554/eLife.38770
(2018) Structure and Function of Sabinene Synthase, a Monoterpene Cyclase That Generates a Highly Strained [3.1.0] Bicyclic Product. Biochemistry. 63, 3147-3159
(2024) Structure of fission yeast transcription factor Pho7 bound to promoter DNA and effect of Pho7 mutations on DNA binding and phosphate homeostasis. Mol Cell Biol. 10.1128/MCB.00132-19
(2019) Structural and Functional Analysis of Ubiquitin-based inhibitors that Target the Backsides of E2 Enzymes. J Mol Biol. 10.1016/j.jmb.2019.09.024
(2019) (2013) Structural and kinetic insights into stimulation of RppH-dependent RNA degradation by the metabolic enzyme DapF. Nucleic Acids Res. 10.1093/nar/gky327
(2018) Structure of DNMT3B homo-oligomer reveals vulnerability to impairment by ICF mutations. Nat Commun. 13, 4249
(2022) Structure-function analysis of STING activation by c[G(2',5')pA(3',5')p] and targeting by antiviral DMXAA. Cell. 154, 748-62
(2013) (2014) Structure of the Arabidopsis Glutamate Receptor-like Channel GLR3.2 Ligand-Binding Domain. Structure. 10.1016/j.str.2020.09.006
(2020) Sub-ångström cryo-EM structure of a prion protofibril reveals a polar clasp.. Nat Struct Mol Biol. 10.1038/s41594-017-0018-0
(2018) Structure of a switchable subtilisin complexed with a substrate and with the activator azide. Biochemistry. 48, 10389-94
(2009) (2013) Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition. Nucleic Acids Res. 44, 2439-50
(2016) (2012) Structures of benzylsuccinate synthase elucidate roles of accessory subunits in glycyl radical enzyme activation and activity. Proc Natl Acad Sci U S A. 111, 10161-6
(2014) Structural Studies of Radical Enzymes in Bacterial Central Metabolism. Ph.D. thesis, Massachusetts Institute of Technology, Cambridge, Massachusetts
(2015) (2014) Structural Studies and Structure Activity Relationships for Novel Computationally Designed Non-nucleoside Inhibitors and Their Interactions With HIV-1 Reverse Transcriptase. Front Mol Biosci. 9, 805187
(2022) Structural and kinetic insights into the mechanism of 5-hydroxyisourate hydrolase from Klebsiella pneumoniae. Acta Crystallogr D Biol Crystallogr. 67, 671-7
(2011) Structural and mechanistic studies on Klebsiella pneumoniae 2-Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase. J Biol Chem. 285, 35446-54
(2010) (2011) Structure and activity of human TMPRSS2 protease implicated in SARS-CoV-2 activation. Nat Chem Biol. 10.1038/s41589-022-01059-7
(2022)