Publications
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Structures of the PutA peripheral membrane flavoenzyme reveal a dynamic substrate-channeling tunnel and the quinone-binding site. Proc Natl Acad Sci U S A. 111, 3389-94
(2014) (2018) Structural insights into a HECT-type E3 ligase AREL1 and its ubiquitination activities . J Biol Chem. 294, 19934-19949
(2019) Structural determinants of HIV-1 Vif susceptibility and DNA binding in APOBEC3F. Nat Commun. 4, 2593
(2013) Structural insight into T cell coinhibition by PD-1H (VISTA). Proc Natl Acad Sci U S A. 10.1073/pnas.1908711117
(2020) (2020) Structure of DNMT1-DNA complex reveals a role for autoinhibition in maintenance DNA methylation. Science. 331, 1036-40
(2011) (2014) Structure-based mechanistic insights into DNMT1-mediated maintenance DNA methylation. Science. 335, 709-12
(2012) Structural similarities between thiamin-binding protein and thiaminase-I suggest a common ancestor. Biochemistry. 47, 1346-57
(2008) Structures of human deoxycytidine kinase product complexes. Acta Crystallogr D Biol Crystallogr. 63, 1201-7
(2007) Structure of a force-conveying cadherin bond essential for inner-ear mechanotransduction. Nature. 492, 128-32
(2012) (2010) Structure and function of the two-component flavin-dependent methanesulfinate monooxygenase within bacterial sulfur assimilation. Biochem Biophys Res Commun. 10.1016/j.bbrc.2019.11.008
(2019) (2022) The structure of the ankyrin-binding site of beta-spectrin reveals how tandem spectrin-repeats generate unique ligand-binding properties. Blood. 113, 5377-84
(2009) Structural insight into the human immunodeficiency virus Vif SOCS box and its role in human E3 ubiquitin ligase assembly. J Virol. 82, 8656-63
(2008) The structures of the anti-tuberculosis antibiotics viomycin and capreomycin bound to the 70S ribosome. Nat Struct Mol Biol. 17, 289-93
(2010) (2016) The shape of the DNA minor groove directs binding by the DNA-bending protein Fis. Genes Dev. 24, 814-26
(2010) Structural determinants for binding of sorting nexin 17 (SNX17) to the cytoplasmic adaptor protein Krev interaction trapped 1 (KRIT1). J Biol Chem. 289, 25362-73
(2014) Structure of the proton-gated urea channel from the gastric pathogen Helicobacter pylori. Nature. 493, 255-8
(2013) Structure determination of BA0150, a putative polysaccharide deacetylase from Bacillus anthracis. Acta Crystallogr F Struct Biol Commun. 70, 156-9
(2014) Structures of the mycobacterial membrane protein MmpL3 reveal its mechanism of lipid transport. PLoS Biol. 19, e3001370
(2021) (2015)