Publications
(2012)
Structurally distinct bacterial TBC-like GAPs link Arf GTPase to Rab1 inactivation to counteract host defenses. Cell. 150, 1029-41
(2012) Structure and conformational change of a replication protein A heterotrimer bound to ssDNA. Genes Dev. 26, 2337-47
(2012) Structure and functional interaction of the extracellular domain of human GABA(B) receptor GBR2. Nat Neurosci. 15, 970-8
(2012) (2012) Structure and permeation mechanism of a mammalian urea transporter. Proc Natl Acad Sci U S A. 109, 11194-9
(2012) (2012) Structure of a calcium-dependent 11R-lipoxygenase suggests a mechanism for Ca2+ regulation. J Biol Chem. 287, 22377-86
(2012) Structure of a force-conveying cadherin bond essential for inner-ear mechanotransduction. Nature. 492, 128-32
(2012) Structure of a glomulin-RBX1-CUL1 complex: inhibition of a RING E3 ligase through masking of its E2-binding surface. Mol Cell. 47, 371-82
(2012) The structure of human GALNS reveals the molecular basis for mucopolysaccharidosis IV A. J Mol Biol. 423, 736-51
(2012) Structure of RPE65 isomerase in a lipidic matrix reveals roles for phospholipids and iron in catalysis. Proc Natl Acad Sci U S A. 109, E2747-56
(2012) Structure of the basal components of a bacterial transporter. Proc Natl Acad Sci U S A. 109, 5446-51
(2012) Structure of the formin-interaction domain of the actin nucleation-promoting factor Bud6. Proc Natl Acad Sci U S A. 109, E3424-33
(2012) Structure of the surface layer of the methanogenic archaean Methanosarcina acetivorans. Proc Natl Acad Sci U S A. 109, 11812-7
(2012) Structure of the ulster strain newcastle disease virus hemagglutinin-neuraminidase reveals auto-inhibitory interactions associated with low virulence. PLoS Pathog. 8, e1002855
(2012) (2012) Structure-based mechanistic insights into DNMT1-mediated maintenance DNA methylation. Science. 335, 709-12
(2012) Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context. Nat Struct Mol Biol. 19, 212-9
(2012) Substrate binds in the S1 site of the F253A mutant of LeuT, a neurotransmitter sodium symporter homologue. EMBO Rep. 13, 861-6
(2012) Substrate-Selective Inhibition of Cyclooxygenase-2: Development and Evaluation of Achiral Profen Probes. ACS Med Chem Lett. 3, 759-763
(2012) (2012) Synthesis, structure, and metalation of two new highly porous zirconium metal-organic frameworks. Inorg Chem. 51, 6443-5
(2012) Specific Btk inhibition suppresses B cell- and myeloid cell-mediated arthritis. Nat Chem Biol. 7, 41-50
(2011) (2011)