Publications
Found 165 results
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(2007) Ensemble refinement of protein crystal structures: validation and application. Structure. 15, 1040-52
(2005) Versatile modes of peptide recognition by the AAA+ adaptor protein SspB. Nat Struct Mol Biol. 12, 520-5
(2015) Structural biology. Division of labor in transhydrogenase by alternating proton translocation and hydride transfer. Science. 347, 178-81
(2016) Uncoupling JAK2 V617F activation from cytokine-induced signalling by modulation of JH2 αC helix.. Biochem J. 473, 1579-91
(2011) The E3 ubiquitin ligase- and protein phosphatase 2A (PP2A)-binding domains of the Alpha4 protein are both required for Alpha4 to inhibit PP2A degradation. J Biol Chem. 286, 17665-71
(2009) The structure of the scaffold nucleoporin Nup120 reveals a new and unexpected domain architecture. Structure. 17, 1082-91
(2018) Crystal structure of arginine-bound lysosomal transporter SLC38A9 in the cytosol-open state. Nat Struct Mol Biol. 25, 522-527
(2014) Crystal structure of the open state of the Neisseria gonorrhoeae MtrE outer membrane channel. PLoS One. 9, e97475
(2011) Crystal structures of CmeR-bile acid complexes from Campylobacter jejuni. Protein Sci. 20, 712-23
(2014) Crystal structures of CusC review conformational changes accompanying folding and transmembrane channel formation. J Mol Biol. 426, 403-11
(2006) Structure of the Escherichia coli ThiS-ThiF complex, a key component of the sulfur transfer system in thiamin biosynthesis. Biochemistry. 45, 11-9
(2014) Characterization of the SAM domain of the PKD-related protein ANKS6 and its interaction with ANKS3. BMC Struct Biol. 14, 17
(2017) Lipid transport by TMEM24 at ER-plasma membrane contacts regulates pulsatile insulin secretion. Science. 10.1126/science.aah6171
(2018) Structures of β-klotho reveal a 'zip code'-like mechanism for endocrine FGF signalling.. Nature. 10.1038/nature25010
(2015) Discovery and crystallography of bicyclic arylaminoazines as potent inhibitors of HIV-1 reverse transcriptase. Bioorg Med Chem Lett. 25, 4824-4827
(2016) Design, Conformation, and Crystallography of 2-Naphthyl Phenyl Ethers as Potent Anti-HIV Agents. ACS Med Chem Lett. 7, 1156-1160
(2013) Structure of a bimodular botulinum neurotoxin complex provides insights into its oral toxicity. PLoS Pathog. 9, e1003690
(2015) Inhibition of ErbB3 by a monoclonal antibody that locks the extracellular domain in an inactive configuration. Proc Natl Acad Sci U S A. 112, 13225-30
(2014) Optimized inhibitors of soluble epoxide hydrolase improve in vitro target residence time and in vivo efficacy. J Med Chem. 57, 7016-30
(2015) Inhibiting oral intoxication of botulinum neurotoxin A complex by carbohydrate receptor mimics. Toxicon. 107, 43-9
(2016) Structural basis of control of inward rectifier Kir2 channel gating by bulk anionic phospholipids. J Gen Physiol. 148, 227-37
(2020) Retinol-binding protein 2 (RBP2) binds monoacylglycerols and modulates gut endocrine signaling and body weight. Sci Adv. 6, eaay8937
(2014) Molecular basis for disruption of E-cadherin adhesion by botulinum neurotoxin A complex. Science. 344, 1405-10
(2018) Crystal Structure of the Double Homeodomain of DUX4 in Complex with DNA. Cell Rep. 25, 2955-2962.e3