Publications
Intermediates in allosteric equilibria of DnaK-ATP interactions with substrate peptides. Acta Crystallogr D Struct Biol. 77, 606-617
(2021) internal tandem duplication disrupts GTPase-activating protein (GAP) binding to activate oncogenic signaling. J Biol Chem. 10.1074/jbc.RA119.011080
(2020) Interpreting the Evolutionary Echoes of a Protein Complex Essential for Inner-Ear Mechanosensation. Mol Biol Evol. 10.1093/molbev/msad057
(2023) The intracellular B30.2 domain of butyrophilin 3A1 binds phosphoantigens to mediate activation of human Vγ9Vδ2 T cells.. Immunity. 40, 490-500
(2014) Intracellular Neutralization of Ricin Toxin by Single-domain Antibodies Targeting the Active Site. J Mol Biol. 10.1016/j.jmb.2020.01.006
(2020) Intramembrane Thiol Oxidoreductases: Evolutionary Convergence and Structural Controversy. Biochemistry. 57, 258-266
(2018) Intramolecular autoinhibition of checkpoint kinase 1 is mediated by conserved basic motifs of the C-terminal kinase-associated 1 domain. J Biol Chem. 292, 19024-19033
(2017) (2023) Intrinsic DNA Shape Accounts for Affinity Differences between Hox-Cofactor Binding Sites. Cell Rep. 24, 2221-2230
(2018) An introduction to RAPD, A NE-CAT Software Package to be added at SER-CAT. SER-CAT Symposium 2016, March 18, 2016
(2014) Inversion of the Side-Chain Stereochemistry of Indvidual Thr or Ile Residues in a Protein Molecule: Impact on the Folding, Stability, and Structure of the ShK Toxin. Angew Chem Int Ed Engl. 56, 3324-3328
(2017) (2023) INVOLVED IN DE NOVO 2-containing complex involved in RNA-directed DNA methylation in Arabidopsis. Proc Natl Acad Sci U S A. 109, 8374-81
(2012) Involvement of the β3-α3 loop of the proline dehydrogenase domain in allosteric regulation of membrane association of proline utilization A.. Biochemistry. 52, 4482-91
(2013) (2019) Isobutanol production freed from biological limits using synthetic biochemistry. Nat Commun. 11, 4292
(2020) Isoform-specific inhibition of FGFR signaling achieved by a de-novo-designed mini-protein. Cell Rep. 41, 111545
(2022) Isonitrile Formation by a Non-Heme Iron(II)-Dependent Oxidase/Decarboxylase. Angew Chem Int Ed Engl. 57, 9707-9710
(2018) Iterative optimization yields Mcl-1-targeting stapled peptides with selective cytotoxicity to Mcl-1-dependent cancer cells. Proc Natl Acad Sci U S A. 115, E886-E895
(2018) JAK2 JH2 Fluorescence Polarization Assay and Crystal Structures for Complexes with Three Small Molecules. ACS Med Chem Lett. 8, 614-617
(2017) A joint x-ray and neutron study on amicyanin reveals the role of protein dynamics in electron transfer. Proc Natl Acad Sci U S A. 107, 6817-22
(2010) K29-linked ubiquitin signaling regulates proteotoxic stress response and cell cycle. Nat Chem Biol. 17, 896-905
(2021) KDM2B Recruitment of the Polycomb Group Complex, PRC1.1, Requires Cooperation between PCGF1 and BCORL1. Structure. 24, 1795-1801
(2016) Key Residues for Catalytic Function and Metal Coordination in a Carotenoid Cleavage Dioxygenase. J Biol Chem. 291, 19401-12
(2016) Kinetic and Structural Characterization of a Flavin-Dependent Putrescine -Hydroxylase from . Biochemistry. 61, 2607-2620
(2022)