Publications
Practical Course in Macromolecular Crystallography. 36th Annual Symposium of The Protein Society, July 7-10, 2022
(2022) Crystal structure of dengue virus type 1 envelope protein in the postfusion conformation and its implications for membrane fusion. J Virol. 83, 4338-44
(2009) Structure of LNX1:Ubc13~Ubiquitin complex reveals the role of additional motifs for the E3 ligase activity of LNX1. J Mol Biol. 10.1016/j.jmb.2018.02.016
(2018) Tuning Inner-Ear Tip-Link Affinity Through Alternatively Spliced Variants of Protocadherin-15. Biochemistry. 10.1021/acs.biochem.7b01075
(2018) Last stop on the road to repair: structure of E. coli DNA ligase bound to nicked DNA-adenylate. Mol Cell. 26, 257-71
(2007) RNA ligase structures reveal the basis for RNA specificity and conformational changes that drive ligation forward. Cell. 127, 71-84
(2006) Cas5d protein processes pre-crRNA and assembles into a cascade-like interference complex in subtype I-C/Dvulg CRISPR-Cas system. Structure. 20, 1574-84
(2012) (2011) Mechanistic manifold in a hemoprotein-catalyzed cyclopropanation reaction with diazoketone. Nat Commun. 14, 7985
(2023) Crystal structure of clustered regularly interspaced short palindromic repeats (CRISPR)-associated Csn2 protein revealed Ca2+-dependent double-stranded DNA binding activity. J Biol Chem. 286, 30759-68
(2011) Synthesis of macrocyclic nucleoside antibacterials and their interactions with MraY. Nat Commun. 13, 7575
(2022) Biophysical Examination of the Calcium-Modulated Nickel-Binding Properties of Human Calprotectin Reveals Conformational Change in the EF-Hand Domains and HisAsp Site. Biochemistry. 10.1021/acs.biochem.8b00415
(2018) Nickel Sequestration by the Host-Defense Protein Human Calprotectin. J Am Chem Soc. 10.1021/jacs.7b01212
(2017) Eukaryote-specific insertion elements control human ARGONAUTE slicer activity. Cell Rep. 3, 1893-900
(2013) (2012) Structural basis for nick recognition by a minimal pluripotent DNA ligase. Nat Struct Mol Biol. 14, 770-8
(2007) (2021) (2022)
Identifying amyloid-related diseases by mapping mutations in low-complexity protein domains to pathologies. Nat Struct Mol Biol. 29, 529-536
(2022) Low-resolution lessons from NE-CAT beamline. SBGrid/NE-CAT Mini-symposium: Low-resolution model building in EM and X-ray crystallography at Harvard Medical School
(2019) Data Collection and Quality. CCP4/APS School in Macromolecular Crystallography: From data collection to structure refinement and beyond, June 18 - 25, 2018
(2018) Using Rapd automated data processing at SER-CAT. 2018 SER-CAT Symposium, April 13, 2018
(2018) An ancient protein-DNA interaction underlying metazoan sex determination. Nat Struct Mol Biol. 22, 442-51
(2015) Rapd - Automated processing/structure determination. Best Practices for the Collection, Processing, Analysis, Transfer and Storage of Data from the New SER-CAT Eiger 16M Detector, April 12, 2018
(2018) NE-CAT: Synchrotron Beamline Designed for Difficult Problems. West Coast Protein Crystallography Workshop, March 19-22, 2017
(2017)