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Vemulapalli, V., Donovan, K. A., Seegar, T. C. M., Rogers, J. M., Bae, M., Lumpkin, R. J., Cao, R., Henke, M. T., Ray, S. S., Fischer, E. S., Cuny, G. D., and Blacklow, S. C. (2021) Targeted Degradation of the Oncogenic Phosphatase SHP2. Biochemistry. 60, 2593-2609
De Schutter, J. W., Morrison, J. P., Morrison, M. J., Ciulli, A., and Imperiali, B. (2017) Targeting Bacillosamine Biosynthesis in Bacterial Pathogens: Development of Inhibitors to a Bacterial Amino-Sugar Acetyltransferase from Campylobacter jejuni. J Med Chem. 60, 2099-2118
Tang, J., Moorthy, R., Hirsch, L. E., Demir, Ö., Baker, Z. D., Naumann, J. A., Jones, K. F. M., Grillo, M. J., Haefner, E. S., Shi, K., Levy, M. J., Gupta, H. B., Aihara, H., Harris, R. S., Amaro, R. E., Levinson, N. M., and Harki, D. A. (2025) Targeting N-Myc in neuroblastoma with selective Aurora kinase A degraders. Cell Chem Biol. 32, 352-362.e10
Sivakumaren, S. Carmen, Shim, H., Zhang, T., Ferguson, F. M., Lundquist, M. R., Browne, C. M., Seo, H. - S., Paddock, M. N., Manz, T. D., Jiang, B., Hao, M. - F., Krishnan, P., Wang, D. G., T Yang, J., Kwiatkowski, N. P., Ficarro, S. B., Cunningham, J. M., Marto, J. A., Dhe-Paganon, S., Cantley, L. C., and Gray, N. S. (2020) Targeting the PI5P4K Lipid Kinase Family in Cancer Using Covalent Inhibitors. Cell Chem Biol. 10.1016/j.chembiol.2020.02.003
Jensen, J. L., Sankhala, R. S., Dussupt, V., Bai, H., Hajduczki, A., Lal, K. G., Chang, W. C., Martinez, E. J., Peterson, C. E., Golub, E. S., Rees, P. A., Mendez-Rivera, L., Zemil, M., Kavusak, E., Mayer, S. V., Wieczorek, L., Kannan, S., Doranz, B. J., Davidson, E., Yang, E. Sung, Zhang, Y., Chen, M., Choe, M., Wang, L., Gromowski, G. D., Koup, R. A., Michael, N. L., Polonis, V. R., Rolland, M., Modjarrad, K., Krebs, S. J., and M Joyce, G. (2023) Targeting the Spike Receptor Binding Domain Class V Cryptic Epitope by an Antibody with Pan-Sarbecovirus Activity. J Virol. 97, e0159622
Jensen, J. L., Sankhala, R. S., Dussupt, V., Bai, H., Hajduczki, A., Lal, K. G., Chang, W. C., Martinez, E. J., Peterson, C. E., Golub, E. S., Rees, P. A., Mendez-Rivera, L., Zemil, M., Kavusak, E., Mayer, S. V., Wieczorek, L., Kannan, S., Doranz, B. J., Davidson, E., Yang, E. Sung, Zhang, Y., Chen, M., Choe, M., Wang, L., Gromowski, G. D., Koup, R. A., Michael, N. L., Polonis, V. R., Rolland, M., Modjarrad, K., Krebs, S. J., and M Joyce, G. (2023) Targeting the Spike Receptor Binding Domain Class V Cryptic Epitope by an Antibody with Pan-Sarbecovirus Activity. J Virol. 97, e0159622
Jensen, J. L., Sankhala, R. S., Dussupt, V., Bai, H., Hajduczki, A., Lal, K. G., Chang, W. C., Martinez, E. J., Peterson, C. E., Golub, E. S., Rees, P. A., Mendez-Rivera, L., Zemil, M., Kavusak, E., Mayer, S. V., Wieczorek, L., Kannan, S., Doranz, B. J., Davidson, E., Yang, E. Sung, Zhang, Y., Chen, M., Choe, M., Wang, L., Gromowski, G. D., Koup, R. A., Michael, N. L., Polonis, V. R., Rolland, M., Modjarrad, K., Krebs, S. J., and M Joyce, G. (2023) Targeting the Spike Receptor Binding Domain Class V Cryptic Epitope by an Antibody with Pan-Sarbecovirus Activity. J Virol. 97, e0159622
Liu, B. Hui, Liu, M., Radhakrishnan, S., Dai, M. - Y., Jaladanki, C. Kumar, Gao, C., Tang, J. Ping, Kumari, K., Go, M. Lin, Vu, K. Anh L., Kwon, J., Seo, H. - S., Song, K., Tian, X., Feng, L., Tan, J. L., Melkonian, A. V., Liu, Z., Wulf, G., Arthanari, H., Qi, J., Dhe-Paganon, S., Clohessy, J. G., Choong, Y. Khai, Sivaraman, J., Fan, H., Tenen, D. G., and Chai, L. (2025) Targeting transcription factors through an IMiD independent zinc finger domain. EMBO Mol Med. 17, 1393-1416
Liu, B. Hui, Liu, M., Radhakrishnan, S., Dai, M. - Y., Jaladanki, C. Kumar, Gao, C., Tang, J. Ping, Kumari, K., Go, M. Lin, Vu, K. Anh L., Kwon, J., Seo, H. - S., Song, K., Tian, X., Feng, L., Tan, J. L., Melkonian, A. V., Liu, Z., Wulf, G., Arthanari, H., Qi, J., Dhe-Paganon, S., Clohessy, J. G., Choong, Y. Khai, Sivaraman, J., Fan, H., Tenen, D. G., and Chai, L. (2025) Targeting transcription factors through an IMiD independent zinc finger domain. EMBO Mol Med. 17, 1393-1416
Takai, H., Xie, Y., de Lange, T., and Pavletich, N. P. (2010) Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes. Genes Dev. 24, 2019-30
Settembre, E. C., Dorrestein, P. C., Zhai, H., Chatterjee, A., McLafferty, F. W., Begley, T. P., and Ealick, S. E. (2004) Thiamin biosynthesis in Bacillus subtilis: structure of the thiazole synthase/sulfur carrier protein complex. Biochemistry. 43, 11647-57
Zhang, L., Lu, X., Lu, J., Liang, H., Dai, Q., Xu, G. - L., Luo, C., Jiang, H., and He, C. (2012) Thymine DNA glycosylase specifically recognizes 5-carboxylcytosine-modified DNA. Nat Chem Biol. 8, 328-30
Morgado-Palacin, L., Brown, J. A., Martinez, T. F., Garcia-Pedrero, J. M., Forouhar, F., S Quinn, A., Reglero, C., Vaughan, J., Heydary, Y. Hajy, Donaldson, C., Rodriguez-Perales, S., Allonca, E., Granda-Diaz, R., Fernandez, A. F., Fraga, M. F., Kim, A. L., Santos-Juanes, J., Owens, D. M., Rodrigo, J. P., Saghatelian, A., and Ferrando, A. A. (2023) The TINCR ubiquitin-like microprotein is a tumor suppressor in squamous cell carcinoma. Nat Commun. 14, 1328
Zhao, S., Lu, J., Pan, B., Fan, H., Byrum, S. D., Xu, C., Kim, A., Guo, Y., Kanchi, K. L., Gong, W., Sun, T., Storey, A. J., Burkholder, N. T., Mackintosh, S. G., Kuhlers, P. C., Edmondson, R. D., Strahl, B. D., Diao, Y., Tackett, A. J., Raab, J. R., Cai, L., Song, J., and Wang, G. Greg (2023) TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons. Nature. 623, 633-642
Le Thomas, A., Stuwe, E., Li, S., Du, J., Marinov, G., Rozhkov, N., Chen, Y. - C. Ariel, Luo, Y., Sachidanandam, R., Toth, K. Fejes, Patel, D., and Aravin, A. A. (2014) Transgenerationally inherited piRNAs trigger piRNA biogenesis by changing the chromatin of piRNA clusters and inducing precursor processing. Genes Dev. 28, 1667-80
Huguenin-Dezot, N., Alonzo, D. A., Heberlig, G. W., Mahesh, M., Nguyen, D. P., Dornan, M. H., Boddy, C. N., T Schmeing, M., and Chin, J. W. (2019) Trapping biosynthetic acyl-enzyme intermediates with encoded 2,3-diaminopropionic acid. Nature. 565, 112-117
Campbell, A. C., Stiers, K. M., Del Campo, J. S. Martin, Mehra-Chaudhary, R., Sobrado, P., and Tanner, J. J. (2020) Trapping conformational states of a flavin-dependent N-monooxygenase in crystallo reveals protein and flavin dynamics. J Biol Chem. 10.1074/jbc.RA120.014750
Golani, L. K., Wallace-Povirk, A., Deis, S. M., Wong, J., Ke, J., Gu, X., Raghavan, S., Wilson, M. R., Li, X., Polin, L., de Waal, P. W., White, K., Kushner, J., O'Connor, C., Hou, Z., H Xu, E., Melcher, K., Dann, C. E., Matherly, L. H., and Gangjee, A. (2016) Tumor Targeting with Novel 6-Substituted Pyrrolo [2,3-d] Pyrimidine Antifolates with Heteroatom Bridge Substitutions via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide Biosynthes. J Med Chem. 59, 7856-76
Golani, L. K., Wallace-Povirk, A., Deis, S. M., Wong, J., Ke, J., Gu, X., Raghavan, S., Wilson, M. R., Li, X., Polin, L., de Waal, P. W., White, K., Kushner, J., O'Connor, C., Hou, Z., H Xu, E., Melcher, K., Dann, C. E., Matherly, L. H., and Gangjee, A. (2016) Tumor Targeting with Novel 6-Substituted Pyrrolo [2,3-d] Pyrimidine Antifolates with Heteroatom Bridge Substitutions via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide Biosynthes. J Med Chem. 59, 7856-76
Golani, L. K., Wallace-Povirk, A., Deis, S. M., Wong, J., Ke, J., Gu, X., Raghavan, S., Wilson, M. R., Li, X., Polin, L., de Waal, P. W., White, K., Kushner, J., O'Connor, C., Hou, Z., H Xu, E., Melcher, K., Dann, C. E., Matherly, L. H., and Gangjee, A. (2016) Tumor Targeting with Novel 6-Substituted Pyrrolo [2,3-d] Pyrimidine Antifolates with Heteroatom Bridge Substitutions via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide Biosynthes. J Med Chem. 59, 7856-76
Chandrasekaran, S., Schneps, C. M., Dunleavy, R., Lin, C., DeOliveira, C. C., Ganguly, A., and Crane, B. R. (2021) Tuning flavin environment to detect and control light-induced conformational switching in Drosophila cryptochrome. Commun Biol. 4, 249
Chandrasekaran, S., Schneps, C. M., Dunleavy, R., Lin, C., DeOliveira, C. C., Ganguly, A., and Crane, B. R. (2021) Tuning flavin environment to detect and control light-induced conformational switching in Drosophila cryptochrome. Commun Biol. 4, 249
Yee, E. F., Dzikovski, B., and Crane, B. R. (2019) Tuning Radical Relay Residues by Proton Management Rescues Protein Electron Hopping. J Am Chem Soc. 141, 17571-17587
Mishra, A., Devarajan, B., Reardon, M. E., Dwivedi, P., Krishnan, V., Cisar, J. O., Das, A., Narayana, S. V. L., and Ton-That, H. (2011) Two autonomous structural modules in the fimbrial shaft adhesin FimA mediate Actinomyces interactions with streptococci and host cells during oral biofilm development. Mol Microbiol. 81, 1205-20
Mishra, A., Devarajan, B., Reardon, M. E., Dwivedi, P., Krishnan, V., Cisar, J. O., Das, A., Narayana, S. V. L., and Ton-That, H. (2011) Two autonomous structural modules in the fimbrial shaft adhesin FimA mediate Actinomyces interactions with streptococci and host cells during oral biofilm development. Mol Microbiol. 81, 1205-20

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