Publications
Found 179 results
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Chemical logic of MraY inhibition by antibacterial nucleoside natural products. Nat Commun. 10, 2917
(2019) (2022) Insight into the molecular basis of substrate recognition by the wall teichoic acid glycosyltransferase TagA. J Biol Chem. 10.1016/j.jbc.2021.101464
(2021) (2012) Structure-Based Evolution of Low Nanomolar O-GlcNAc Transferase Inhibitors. J Am Chem Soc. 10.1021/jacs.8b07328
(2018) The Third Coiled Coil Domain of Atg11 Is Required for Shaping Mitophagy Initiation Sites. J Mol Biol. 10.1016/j.jmb.2020.08.025
(2020) Peptide inhibitors of bacterial protein synthesis with broad spectrum and SbmA-independent bactericidal activity against clinical pathogens. J Med Chem. 10.1021/acs.jmedchem.0c00665
(2020) (2012) Now on display: a gallery of group II intron structures at different stages of catalysis. Mob DNA. 4, 14
(2013) Solving nucleic acid structures by molecular replacement: examples from group II intron studies. Acta Crystallogr D Biol Crystallogr. 69, 2174-85
(2013) Antibiotic that inhibits -translation blocks binding of EF-Tu to tmRNA but not to tRNA. mBio. 10.1128/mbio.01461-23
(2023) Atomic structure of the KEOPS complex: an ancient protein kinase-containing molecular machine. Mol Cell. 32, 259-75
(2008) Crystal and solution structures of an odorant-binding protein from the southern house mosquito complexed with an oviposition pheromone. Proc Natl Acad Sci U S A. 107, 19102-7
(2010) Structure-Activity Relationship Study of Covalent Pan-phosphatidylinositol 5-Phosphate 4-Kinase Inhibitors. ACS Med Chem Lett. 11, 346-352
(2020) Discovery and Structure-Activity Relationship Study of ()-5-Methylenethiazolidin-4-one Derivatives as Potent and Selective Pan-phosphatidylinositol 5-Phosphate 4-Kinase Inhibitors. J Med Chem. 10.1021/acs.jmedchem.0c00227
(2020) X-ray structures define human P2X(3) receptor gating cycle and antagonist action. Nature. 538, 66-71
(2016) Structure of human phosphopantothenoylcysteine synthetase at 2.3 A resolution. Structure. 11, 927-36
(2003) Unusual space-group pseudosymmetry in crystals of human phosphopantothenoylcysteine decarboxylase. Acta Crystallogr D Biol Crystallogr. 59, 1762-6
(2003) (2021) Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-κB Signaling Adaptation.. Cell Rep. 27, 1165-1175.e5
(2019) Visualizing group II intron dynamics between the first and second steps of splicing. Nat Commun. 11, 2837
(2020) (2019) Crystal structure of human mitochondrial acyl-CoA thioesterase (ACOT2). Biochem Biophys Res Commun. 385, 630-3
(2009) Total chemical synthesis of biologically active vascular endothelial growth factor. Angew Chem Int Ed Engl. 50, 8029-33
(2011) (2016)