Publications
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A useful epitope tag derived from maltose binding protein. Protein Sci. 10.1002/pro.4088
(2021) The transcription factor FoxP3 can fold into two dimerization states with divergent implications for regulatory T cell function and immune homeostasis.. Immunity. 55, 1354-1369.e8
(2022) Mechanism of selective recognition of Lys48-linked polyubiquitin by macrocyclic peptide inhibitors of proteasomal degradation. Nat Commun. 14, 7212
(2023) The structure of the scaffold nucleoporin Nup120 reveals a new and unexpected domain architecture. Structure. 17, 1082-91
(2009) (2015) Crystal structure of the open state of the Neisseria gonorrhoeae MtrE outer membrane channel. PLoS One. 9, e97475
(2014) (2011) Crystal structures of CusC review conformational changes accompanying folding and transmembrane channel formation. J Mol Biol. 426, 403-11
(2014) Crystal structure of arginine-bound lysosomal transporter SLC38A9 in the cytosol-open state. Nat Struct Mol Biol. 25, 522-527
(2018) A conformational change in the N terminus of SLC38A9 signals mTORC1 activation. Structure. 29, 426-432.e8
(2021) Structure of the Escherichia coli ThiS-ThiF complex, a key component of the sulfur transfer system in thiamin biosynthesis. Biochemistry. 45, 11-9
(2006) Characterization of the SAM domain of the PKD-related protein ANKS6 and its interaction with ANKS3. BMC Struct Biol. 14, 17
(2014) Lipid transport by TMEM24 at ER-plasma membrane contacts regulates pulsatile insulin secretion. Science. 10.1126/science.aah6171
(2017) Atomic substitution reveals the structural basis for substrate adenine recognition and removal by adenine DNA glycosylase. Proc Natl Acad Sci U S A. 106, 18497-502
(2009) High-resolution crystal structure of HA33 of botulinum neurotoxin type B progenitor toxin complex. Biochem Biophys Res Commun. 446, 568-73
(2014) Structure of coatomer cage proteins and the relationship among COPI, COPII, and clathrin vesicle coats. Cell. 142, 123-32
(2010) Synthesis and structure of duplex DNA containing the genotoxic nucleobase lesion N7-methylguanine. J Am Chem Soc. 130, 11570-1
(2008) Mechanism of DNA Lesion Homing and Recognition by the Uvr Nucleotide Excision Repair System. Research (Wash D C). 2019, 5641746
(2019) Structures of β-klotho reveal a 'zip code'-like mechanism for endocrine FGF signalling.. Nature. 10.1038/nature25010
(2018) Discovery and crystallography of bicyclic arylaminoazines as potent inhibitors of HIV-1 reverse transcriptase. Bioorg Med Chem Lett. 25, 4824-4827
(2015) Design, Conformation, and Crystallography of 2-Naphthyl Phenyl Ethers as Potent Anti-HIV Agents. ACS Med Chem Lett. 7, 1156-1160
(2016) Structure of a bimodular botulinum neurotoxin complex provides insights into its oral toxicity. PLoS Pathog. 9, e1003690
(2013) Unraveling Complex Local Protein Environments with 4-Cyano-l-phenylalanine. J Phys Chem B. 126, 8957-8969
(2022) Inhibition of ErbB3 by a monoclonal antibody that locks the extracellular domain in an inactive configuration. Proc Natl Acad Sci U S A. 112, 13225-30
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