Publications
Found 225 results
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Geometric Lessons and Design Strategies for Nanoscale Protein Cages. ACS Nano. 10.1021/acsnano.0c07167
(2021) PIM-induced phosphorylation of Notch3 promotes breast cancer tumorigenicity in a CSL-independent fashion. J Biol Chem. 10.1016/j.jbc.2021.100593
(2021) (2011) Structure-Guided Development of a Potent and Selective Non-covalent Active-Site Inhibitor of USP7. Cell Chem Biol. 10.1016/j.chembiol.2017.09.003
(2017) Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression. Nat Commun. 10, 2261
(2019) Probing the structure and function of the protease domain of botulinum neurotoxins using single-domain antibodies. PLoS Pathog. 18, e1010169
(2022) Two VHH Antibodies Neutralize Botulinum Neurotoxin E1 by Blocking Its Membrane Translocation in Host Cells. Toxins (Basel). 10.3390/toxins12100616
(2020) The hypothetical protein P47 of Clostridium botulinum E1 strain Beluga has a structural topology similar to bactericidal/permeability-increasing protein. Toxicon. 10.1016/j.toxicon.2017.10.012
(2017) Structural Insights into Rational Design of Single-Domain Antibody-Based Antitoxins against Botulinum Neurotoxins. Cell Rep. 30, 2526-2539.e6
(2020) Structural and biochemical characterization of the protease domain of the mosaic botulinum neurotoxin type HA. Pathog Dis. 10.1093/femspd/fty044
(2018) A viral-fusion-peptide-like molecular switch drives membrane insertion of botulinum neurotoxin A1. Nat Commun. 9, 5367
(2018) Structure-Based Design and Synthesis of an HIV-1 Entry Inhibitor Exploiting X-Ray and Thermodynamic Characterization. ACS Med Chem Lett. 4, 338-343
(2013) Structure-Function Analyses of the Interactions between Rab11 and Rab14 Small GTPases with Their Shared Effector Rab Coupling Protein (RCP). J Biol Chem. 290, 18817-32
(2015) Structural and functional analysis of FIP2 binding to the endosome-localised Rab25 GTPase. Biochim Biophys Acta. 1834, 2679-90
(2013) Structural and functional analyses reveal promiscuous and species specific use of ephrin receptors by Cedar virus. Proc Natl Acad Sci U S A. 116, 20707-20715
(2019) Structural and biochemical studies of the open state of Lys48-linked diubiquitin. Biochim Biophys Acta. 1823, 2046-56
(2012) On the predictability of the orientation of protein domains joined by a spanning alpha-helical linker. Protein Eng Des Sel. 28, 491-9
(2015) (2012) Thiamin pyrimidine biosynthesis in Candida albicans : a remarkable reaction between histidine and pyridoxal phosphate. J Am Chem Soc. 134, 9157-9
(2012) Structure of a designed protein cage that self-assembles into a highly porous cube. Nat Chem. 6, 1065-71
(2014) Structure and flexibility of nanoscale protein cages designed by symmetric self-assembly. J Am Chem Soc. 135, 7738-43
(2013) Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function. Protein Sci. 19, 1031-43
(2010) An approach to crystallizing proteins by metal-mediated synthetic symmetrization. Protein Sci. 20, 1876-90
(2011) (2012) Non-3D domain swapped crystal structure of truncated zebrafish alphaA crystallin. Protein Sci. 19, 1978-84
(2010)