Publications
(2011)
Structure of human O-GlcNAc transferase and its complex with a peptide substrate. Nature. 469, 564-7
(2011) Structure of prokaryotic polyamine deacetylase reveals evolutionary functional relationships with eukaryotic histone deacetylases. Biochemistry. 50, 1808-17
(2011) Structure-based development of small molecule PFKFB3 inhibitors: a framework for potential cancer therapeutic agents targeting the Warburg effect. PLoS One. 6, e24179
(2011) Synthetic symmetrization in the crystallization and structure determination of CelA from Thermotoga maritima. Protein Sci. 20, 168-78
(2011) (2011) (2011) (2011) Tracking a defined route for O₂ migration in a dioxygen-activating diiron enzyme.. Proc Natl Acad Sci U S A. 108, 14795-800
(2011) Unique active site promotes error-free replication opposite an 8-oxo-guanine lesion by human DNA polymerase iota. Proc Natl Acad Sci U S A. 108, 3210-5
(2011) Variation in mutation rates caused by RB69pol fidelity mutants can be rationalized on the basis of their kinetic behavior and crystal structures. J Mol Biol. 406, 558-70
(2011) β₂-microglobulin forms three-dimensional domain-swapped amyloid fibrils with disulfide linkages.. Nat Struct Mol Biol. 18, 49-55
(2011) Adapting federated cyberinfrastructure for shared data collection facilities in structural biology. J Synchrotron Radiat. 19, 462-7
(2012) Amyloid β-sheet mimics that antagonize protein aggregation and reduce amyloid toxicity.. Nat Chem. 4, 927-33
(2012) (2012) (2012) (2012) ATPase-dependent role of the atypical kinase Rio2 on the evolving pre-40S ribosomal subunit. Nat Struct Mol Biol. 19, 1316-23
(2012) ATPase-dependent role of the atypical kinase Rio2 on the evolving pre-40S ribosomal subunit. Nat Struct Mol Biol. 19, 1316-23
(2012) Balanced interactions of calcineurin with AKAP79 regulate Ca2+-calcineurin-NFAT signaling. Nat Struct Mol Biol. 19, 337-45
(2012) Cas5d protein processes pre-crRNA and assembles into a cascade-like interference complex in subtype I-C/Dvulg CRISPR-Cas system. Structure. 20, 1574-84
(2012) Charged amino acids (R83, E567, D617, E625, R669, and K678) of CusA are required for metal ion transport in the Cus efflux system. J Mol Biol. 422, 429-41
(2012) Charged amino acids (R83, E567, D617, E625, R669, and K678) of CusA are required for metal ion transport in the Cus efflux system. J Mol Biol. 422, 429-41
(2012) Chemical synthesis and X-ray structure of a heterochiral {D-protein antagonist plus vascular endothelial growth factor} protein complex by racemic crystallography. Proc Natl Acad Sci U S A. 109, 14779-84
(2012) (2012)