Publications

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Maehigashi, T., Dunkle, J. A., Miles, S. J., and Dunham, C. M. (2014) Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops. Proc Natl Acad Sci U S A. 111, 12740-5
Maehigashi, T., Dunkle, J. A., Miles, S. J., and Dunham, C. M. (2014) Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops. Proc Natl Acad Sci U S A. 111, 12740-5
Wittenborn, E. C., Cohen, S. E., Merrouch, M., Léger, C., Fourmond, V., Dementin, S., and Drennan, C. L. (2019) Structural insight into metallocofactor maturation in carbon monoxide dehydrogenase. J Biol Chem. 294, 13017-13026
Wittenborn, E. C., Cohen, S. E., Merrouch, M., Léger, C., Fourmond, V., Dementin, S., and Drennan, C. L. (2019) Structural insight into metallocofactor maturation in carbon monoxide dehydrogenase. J Biol Chem. 294, 13017-13026
Fribourgh, J. L., Nguyen, H. C., Matreyek, K. A., Alvarez, F. Joan D., Summers, B. J., Dewdney, T. G., Aiken, C., Zhang, P., Engelman, A., and Xiong, Y. (2014) Structural insight into HIV-1 restriction by MxB. Cell Host Microbe. 16, 627-638
Higgins, L. J., Yan, F., Liu, P., Liu, H. -wen, and Drennan, C. L. (2005) Structural insight into antibiotic fosfomycin biosynthesis by a mononuclear iron enzyme. Nature. 437, 838-44
Hung, K. - W., Chang, Y. - W., Eng, E. T., Chen, J. - H., Chen, Y. - C., Sun, Y. - J., Hsiao, C. - D., Dong, G., Spasov, K. A., Unger, V. M., and Huang, T. - H. (2010) Structural fold, conservation and Fe(II) binding of the intracellular domain of prokaryote FeoB. J Struct Biol. 170, 501-12
Wittenborn, E. C. (2017) Structural Enzymology of Bacterial Carbon Fixation and Storage. Ph.D. thesis, Massachusetts Institute of Technology, Cambridge, Massachusetts
Rudolph, M. J., Davis, S. A., Haque, H. M. Emranul, Weis, D. D., Vance, D. J., Piazza, C. Lyn, Ejemel, M., Cavacini, L., Wang, Y., M Mbow, L., Gilmore, R. D., and Mantis, N. J. (2023) Structural Elucidation of a Protective B Cell Epitope on Outer Surface Protein C (OspC) of the Lyme Disease Spirochete, Borreliella burgdorferi. mBio. 10.1128/mbio.02981-22
Dowling, D. P., Kung, Y., Croft, A. K., Taghizadeh, K., Kelly, W. L., Walsh, C. T., and Drennan, C. L. (2016) Structural elements of an NRPS cyclization domain and its intermodule docking domain. Proc Natl Acad Sci U S A. 113, 12432-12437
Dowling, D. P., Kung, Y., Croft, A. K., Taghizadeh, K., Kelly, W. L., Walsh, C. T., and Drennan, C. L. (2016) Structural elements of an NRPS cyclization domain and its intermodule docking domain. Proc Natl Acad Sci U S A. 113, 12432-12437
Malakhova, M., Kurinov, I., Liu, K., Zheng, D., D'Angelo, I., Shim, J. - H., Steinman, V., Bode, A. M., and Dong, Z. (2009) Structural diversity of the active N-terminal kinase domain of p90 ribosomal S6 kinase 2. PLoS One. 4, e8044
Malakhova, M., Kurinov, I., Liu, K., Zheng, D., D'Angelo, I., Shim, J. - H., Steinman, V., Bode, A. M., and Dong, Z. (2009) Structural diversity of the active N-terminal kinase domain of p90 ribosomal S6 kinase 2. PLoS One. 4, e8044
Devlin, J. R., Alonso, J. A., Ayres, C. M., Keller, G. L. J., Bobisse, S., Kooi, C. W. Vander, Coukos, G., Gfeller, D., Harari, A., and Baker, B. M. (2020) Structural dissimilarity from self drives neoepitope escape from immune tolerance. Nat Chem Biol. 10.1038/s41589-020-0610-1
Donaldson, T. M., Ting, L. - M., Zhan, C., Shi, W., Zheng, R., Almo, S. C., and Kim, K. (2014) Structural determinants of the 5'-methylthioinosine specificity of Plasmodium purine nucleoside phosphorylase. PLoS One. 9, e84384
Choudhary, D., Narui, Y., Neel, B. L., Wimalasena, L. N., Klanseck, C. F., De-la-Torre, P., Chen, C., Araya-Secchi, R., Tamilselvan, E., and Sotomayor, M. (2020) Structural determinants of protocadherin-15 mechanics and function in hearing and balance perception. Proc Natl Acad Sci U S A. 10.1073/pnas.1920444117
Goris, M., Magin, R. S., Foyn, H., Myklebust, L. M., Varland, S., Ree, R., Drazic, A., Bhambra, P., Støve, S. I., Baumann, M., Haug, B. Erik, Marmorstein, R., and Arnesen, T. (2018) Structural determinants and cellular environment define processed actin as the sole substrate of the N-terminal acetyltransferase NAA80. Proc Natl Acad Sci U S A. 115, 4405-4410
Faust, T. B., Yoon, H., Nowak, R. P., Donovan, K. A., Li, Z., Cai, Q., Eleuteri, N. A., Zhang, T., Gray, N. S., and Fischer, E. S. (2020) Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15. Nat Chem Biol. 16, 7-14
Zheng, C., Page, R. C., Das, V., Nix, J. C., Wigren, E., Misra, S., and Zhang, B. (2013) Structural characterization of carbohydrate binding by LMAN1 protein provides new insight into the endoplasmic reticulum export of factors V (FV) and VIII (FVIII). J Biol Chem. 288, 20499-509
Tang, H., Demir, Ö., Kurniawan, F., Brown, W. L., Shi, K., Moeller, N. H., Carpenter, M. A., Belica, C., Orellana, K., Du, G., LeBeau, A. M., Amaro, R. E., Harris, R. S., and Aihara, H. (2021) Structural Characterization of a Minimal Antibody against Human APOBEC3B. Viruses. 10.3390/v13040663
Tang, H., Demir, Ö., Kurniawan, F., Brown, W. L., Shi, K., Moeller, N. H., Carpenter, M. A., Belica, C., Orellana, K., Du, G., LeBeau, A. M., Amaro, R. E., Harris, R. S., and Aihara, H. (2021) Structural Characterization of a Minimal Antibody against Human APOBEC3B. Viruses. 10.3390/v13040663
Gonzalez, R., Soule, J., Phan, N., Wicht, D. K., and Dowling, D. P. (2024) Structural, biophysical, and biochemical insights into C-S bond cleavage by dimethylsulfone monooxygenase. Proc Natl Acad Sci U S A. 121, e2401858121
Huang, H., Deng, Z., Vladimirova, O., Wiedmer, A., Lu, F., Lieberman, P. M., and Patel, D. J. (2016) Structural basis underlying viral hijacking of a histone chaperone complex. Nat Commun. 7, 12707
Schureck, M. A., Meisner, J., Hoffer, E. D., Wang, D., Onuoha, N., Cho, S. Ei, Lollar, P., and Dunham, C. M. (2019) Structural basis of transcriptional regulation by the HigA antitoxin. Mol Microbiol. 10.1111/mmi.14229
Weixlbaumer, A., Leon, K., Landick, R., and Darst, S. A. (2013) Structural basis of transcriptional pausing in bacteria. Cell. 152, 431-41

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