Publications
(2016)
Serotonin transporter-ibogaine complexes illuminate mechanisms of inhibition and transport. Nature. 569, 141-145
(2019) Chemical and structural investigation of the paroxetine-human serotonin transporter complex. Elife. 10.7554/eLife.56427
(2020) The Heme-Lys Cross-Link in Cytochrome P460 Promotes Catalysis by Enforcing Secondary Coordination Sphere Architecture. Biochemistry. 59, 2289-2298
(2020) Structural basis for recognition of diverse antidepressants by the human serotonin transporter. Nat Struct Mol Biol. 10.1038/s41594-018-0026-8
(2018) Structure of the metal-dependent deacetylase LpxC from Yersinia enterocolitica complexed with the potent inhibitor CHIR-090 . Biochemistry. 50, 258-65
(2011) Crystallographic Characterization of the Carbonylated A-Cluster in Carbon Monoxide Dehydrogenase/Acetyl-CoA Synthase. ACS Catal. 10, 9741-9746
(2020) (2024) Crystal structure of the human heterogeneous ribonucleoprotein A18 RNA-recognition motif. Acta Crystallogr F Struct Biol Commun. 73, 209-214
(2017) Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity. Cell. 158, 132-42
(2014) Structural characteristics of lipocalin allergens: Crystal structure of the immunogenic dog allergen Can f 6. PLoS One. 14, e0213052
(2019) (2015) SARS-CoV-2 evolution in an immunocompromised host reveals shared neutralization escape mechanisms. Cell. 10.1101/2020.11.13.381533
(2021) Vaccine-elicited receptor-binding site antibodies neutralize two New World hemorrhagic fever arenaviruses. Nat Commun. 9, 1884
(2018) Crystal Structure of the RNA Lariat Debranching Enzyme Dbr1 with Hydrolyzed Phosphorothioate RNA Product. Biochemistry. 10.1021/acs.biochem.2c00590
(2022) Metal dependence and branched RNA cocrystal structures of the RNA lariat debranching enzyme Dbr1. Proc Natl Acad Sci U S A. 113, 14727-14732
(2016) Human CaaX protease ZMPSTE24 expressed in yeast: Structure and inhibition by HIV protease inhibitors. Protein Sci. 26, 242-257
(2017) Altered Binding of Tumor Antigenic Peptides to MHC Class I Affects CD8 T Cell-Effector Responses. Cancer Immunol Res. 6, 1524-1536
(2018) Structural insights into inhibition of lipid I production in bacterial cell wall synthesis. Nature. 533, 557-560
(2016) Crystal structure of MraY, an essential membrane enzyme for bacterial cell wall synthesis. Science. 341, 1012-1016
(2013) Regulation of the intersubunit ammonia tunnel in Mycobacterium tuberculosis glutamine-dependent NAD+ synthetase. Biochem J. 443, 417-26
(2012) A DNA G-quadruplex/i-motif hybrid. Nucleic Acids Res. 10.1093/nar/gkz1008
(2019) Crystal Structure of a Tetrameric DNA Fold-Back Quadruplex. J Am Chem Soc. 10.1021/jacs.8b10153
(2018) (2008) Screening for Proline Analog Inhibitors of the Proline Cycle Enzyme PYCR1. J Biol Chem. 10.1074/jbc.RA120.016106
(2020)