Publications
ppGpp Coordinates Nucleotide and Amino-Acid Synthesis in E. coli During Starvation.. Mol Cell. 10.1016/j.molcel.2020.08.005
(2020) Uncovering the enzymes that catalyze the final steps in oxytetracycline biosynthesis. J Am Chem Soc. 135, 7138-41
(2013) LIN28 Zinc Knuckle Domain Is Required and Sufficient to Induce let-7 Oligouridylation. Cell Rep. 18, 2664-2675
(2017) Affinity-based capture and identification of protein effectors of the growth regulator ppGpp. Nat Chem Biol. 15, 141-150
(2019) Etesevimab in combination with JS026 neutralizing SARS-CoV-2 and its variants. Emerg Microbes Infect. 11, 548-551
(2022) Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger. Nature. 459, 847-51
(2009) Intermediates in allosteric equilibria of DnaK-ATP interactions with substrate peptides. Acta Crystallogr D Struct Biol. 77, 606-617
(2021) Molecular and structural basis of olfactory sensory neuron axon coalescence by Kirrel receptors. Cell Rep. 37, 109940
(2021) Structural insights into glutathione-mediated activation of the master regulator PrfA in Listeria monocytogenes. Protein Cell. 8, 308-312
(2017) Identification of MRTX1133, a Noncovalent, Potent, and Selective KRAS Inhibitor. J Med Chem. 10.1021/acs.jmedchem.1c01688
(2021) Structural basis for action by diverse antidepressants on biogenic amine transporters. Nature. 503, 141-5
(2013) Conformational equilibria in allosteric control of Hsp70 chaperones. Mol Cell. 10.1016/j.molcel.2021.07.039
(2021) Crystal structure of human IRAK1. Proc Natl Acad Sci U S A. 10.1073/pnas.1714386114
(2017) Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context. Nat Struct Mol Biol. 19, 212-9
(2012) Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression. Cell. 141, 1183-94
(2010) Substrate binds in the S1 site of the F253A mutant of LeuT, a neurotransmitter sodium symporter homologue. EMBO Rep. 13, 861-6
(2012) Potent monoclonal antibody-mediated neutralization of a divergent Hendra virus variant. Proc Natl Acad Sci U S A. 119, e2122769119
(2022) (2008) Programming A Molecular Relay for Ultrasensitive Biodetection through (129)Xe NMR.. Angew Chem Int Ed Engl. 55, 1733-6
(2016) Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains. Proc Natl Acad Sci U S A. 120, e2214556120
(2023) (2009) Heterochromatin protein Sir3 induces contacts between the amino terminus of histone H4 and nucleosomal DNA. Proc Natl Acad Sci U S A. 110, 8495-500
(2013) Structural Basis for the Lesion-scanning Mechanism of the MutY DNA Glycosylase. J Biol Chem. 292, 5007-5017
(2017) (2008) DNA repair. Mechanism of DNA interstrand cross-link processing by repair nuclease FAN1. Science. 346, 1127-30
(2014)