Publications
An ensemble of lipoxygenase structures reveals novel conformations of the Fe coordination sphere. Protein Sci. 10.1002/pro.3602
(2019) An ensemble of lipoxygenase structures reveals novel conformations of the Fe coordination sphere. Protein Sci. 10.1002/pro.3602
(2019) An ensemble of lipoxygenase structures reveals novel conformations of the Fe coordination sphere. Protein Sci. 10.1002/pro.3602
(2019) Extension of the Notch intracellular domain ankyrin repeat stack by NRARP promotes feedback inhibition of Notch signaling. Sci Signal. 10.1126/scisignal.aay2369
(2019) Fluorescent indomethacin-dansyl conjugates utilize the membrane-binding domain of cyclooxygenase-2 to block the opening to the active site. J Biol Chem. 10.1074/jbc.RA119.007405
(2019) A Glycoconjugated SIRT2 Inhibitor with Aqueous Solubility Allows Structure-Based Design of SIRT2 Inhibitors. ACS Chem Biol. 14, 1802-1810
(2019) High-resolution crystal structures of ribosome-bound chloramphenicol and erythromycin provide the ultimate basis for their competition. RNA. 10.1261/rna.069260.118
(2019) HORMA Domain Proteins and a Trip13-like ATPase Regulate Bacterial cGAS-like Enzymes to Mediate Bacteriophage Immunity. Mol Cell. 10.1016/j.molcel.2019.12.009
(2019) Human keratin 1/10-1B tetramer structures reveal a knob-pocket mechanism in intermediate filament assembly. EMBO J. 10.15252/embj.2018100741
(2019) Identification of a Helical Segment within the Intrinsically Disordered Region of the PCSK9 Prodomain. J Mol Biol. 431, 885-903
(2019) Identification of Three Sequence Motifs in the Transcription Termination Factor Sen1 that Mediate Direct Interactions with Nrd1. Structure. 27, 1156-1161.e4
(2019) Influenza Antigen Engineering Focuses Immune Responses to a Subdominant but Broadly Protective Viral Epitope. Cell Host Microbe. 25, 827-835.e6
(2019) (2019) (2019) LRRK2 binds to the Rab32 subfamily in a GTP-dependent manner its armadillo domain. Small GTPases. 10.1080/21541248.2019.1666623
(2019) Mechanically rigid supramolecular assemblies formed from an Fmoc-guanine conjugated peptide nucleic acid. Nat Commun. 10, 5256
(2019) Mechanically rigid supramolecular assemblies formed from an Fmoc-guanine conjugated peptide nucleic acid. Nat Commun. 10, 5256
(2019) The mechanosensitive ion channel TRAAK is localized to the mammalian node of Ranvier. Elife. 10.7554/eLife.50403
(2019) MmpL3 is a lipid transporter that binds trehalose monomycolate and phosphatidylethanolamine. Proc Natl Acad Sci U S A. 10.1073/pnas.1901346116
(2019) Multidomain Convergence of Argonaute during RISC Assembly Correlates with the Formation of Internal Water Clusters. Mol Cell. 75, 725-740.e6
(2019) A mutually-induced conformational fit underlies Ca-directed interactions between calmodulin and the proximal C terminus of KCNQ4 K channels. J Biol Chem. 10.1074/jbc.RA118.006857
(2019) The nascent RNA binding complex SFiNX licenses piRNA-guided heterochromatin formation. Nat Struct Mol Biol. 26, 720-731
(2019) The nascent RNA binding complex SFiNX licenses piRNA-guided heterochromatin formation. Nat Struct Mol Biol. 26, 720-731
(2019) NE-CAT: Crystallography Beamlines for Challenging Structural Biology Research. Award Winners and Abstracts of the 33rd Annual Symposium of The Protein Society; Seattle, Washington, June 30-July 3, 2019. 28, 12-211
(2019) NE-CAT: Crystallography Beamlines for Challenging Structural Biology Research. 2019 Annual Meeting of the American Crystallographic Association, July 20-24, 2019
(2019)