COVID-19 Research

NECAT is giving priority to COVID-19 research while accepting all GUP beamtime requests.

COVID-19 Research

Novel Coronavirus

On June 15, 2020, Argonne and the Advanced Photon Source started a phased, coordinated process to return to normal operations. The first phase of the transition is from minimum safe operations – the state APS was in starting March 21 – to a stage known as limited operations.

Advances in COVID-19 Prevention and Treatment Enabled by Structural Biology Research Workshop

The emergence of the novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) -- the etiologic agent responsible for the current outbreak of COVID-19 -- mobilized research communities around the world to investigate the virus and the disease at unprecedented speed. To deliver information suitable for the development of vaccines, therapeutics, and diagnostics, researchers representing multiple disciplines and institutions quickly initiated broad collaborations, while DOE user facilities provided unlimited access to resources necessary for this research.

Office Hours

Questions?

....Answers Provided.

 

Zoom-based office hours to answer questions regarding using NE-CAT, data processing, structure solution or anything else x-ray crystallography-related available weekly.

Thursday, 1:00 - 3:00 PM Central Time

Request the Zoom link via email.

Activity profiling and crystal structures of inhibitor-bound SARS-CoV-2 papain-like protease: A framework for anti-COVID-19 drug design.

A Cryptic Site of Vulnerability on the Receptor Binding Domain of the SARS-CoV-2 Spike Glycoprotein

SARS-CoV-2 is a zoonotic virus that has caused a pandemic of severe respiratory disease—COVID-19— within several months of its initial identification. Comparable to the first SARS-CoV, this novel coronavirus’s surface Spike (S) glycoprotein mediates cell entry via the human ACE-2 receptor, and, thus, is the principal target for the development of vaccines and immunotherapeutics.

Illinois Stay-At-Home Order

Per the Illinois Stay-At-Home Order, NE-CAT has only has available beamtime for COVID-19 related research.  On-site access is not available and all data collection must be conducted remotely.


TO:                All Employees

Rapid Access Beamtime for COVID-19 Research

On February 18, 2020, in support of the COVID-19 outbreak, NE-CAT provided rapid access beamtime to researchers from the Walter Reed Army Institute of Research working on the the SARS-CoV-2 S glycoprotein receptor-binding-domain. The novel coronavirus's surface Spike (S) glycoprotein mediates cell entry via the human ACE-2 receptor, and is the principal target for the development of vaccines and immunotherapeutics.

Rapid Access Beamtime is available for all research projects related to COVID-19.

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