Zoom-based office hours to answer questions regarding using NE-CAT, data processing, structure solution or anything else x-ray crystallography-related available weekly.
Thursday, 1:00 - 3:00 PM Central Time
Request the Zoom link via email.
Structural work on SARS-CoV-2 papain-like protease, SARS-CoV-2-PLpro, required for processing viral polyproteins to generate a functional replicase complex and enable viral spread has been featured as a highlight on the APS website.
SARS-CoV-2 is a zoonotic virus that has caused a pandemic of severe respiratory disease—COVID-19— within several months of its initial identification. Comparable to the first SARS-CoV, this novel coronavirus’s surface Spike (S) glycoprotein mediates cell entry via the human ACE-2 receptor, and, thus, is the principal target for the development of vaccines and immunotherapeutics.
Per the Illinois Stay-At-Home Order, NE-CAT has only has available beamtime for COVID-19 related research. On-site access is not available and all data collection must be conducted remotely.
TO: All Employees
On February 18, 2020, in support of the COVID-19 outbreak, NE-CAT provided rapid access beamtime to researchers from the Walter Reed Army Institute of Research working on the the SARS-CoV-2 S glycoprotein receptor-binding-domain. The novel coronavirus's surface Spike (S) glycoprotein mediates cell entry via the human ACE-2 receptor, and is the principal target for the development of vaccines and immunotherapeutics.
Rapid Access Beamtime is available for all research projects related to COVID-19.