Publications
(2013) Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase. Cell. 153, 1094-107
(2013) Dieselzymes: development of a stable and methanol tolerant lipase for biodiesel production by directed evolution. Biotechnol Biofuels. 6, 70
(2013) Dieselzymes: development of a stable and methanol tolerant lipase for biodiesel production by directed evolution. Biotechnol Biofuels. 6, 70
(2013) Eukaryote-specific insertion elements control human ARGONAUTE slicer activity. Cell Rep. 3, 1893-900
(2013) Exploring the molecular determinants of substrate-selective inhibition of cyclooxygenase-2 by lumiracoxib. Bioorg Med Chem Lett. 23, 5860-4
(2013) Glucose-neopentyl glycol (GNG) amphiphiles for membrane protein study. Chem Commun (Camb). 49, 2287-9
(2013) Glucose-neopentyl glycol (GNG) amphiphiles for membrane protein study. Chem Commun (Camb). 49, 2287-9
(2013) Inhibitors that stabilize a closed RAF kinase domain conformation induce dimerization. Nat Chem Biol. 9, 428-36
(2013) Involvement of the β3-α3 loop of the proline dehydrogenase domain in allosteric regulation of membrane association of proline utilization A.. Biochemistry. 52, 4482-91
(2013) Leukotriene biosynthesis inhibitor MK886 impedes DNA polymerase activity. Chem Res Toxicol. 26, 221-32
(2013) Lipoamide channel-binding sulfonamides selectively inhibit mycobacterial lipoamide dehydrogenase. Biochemistry. 52, 9375-84
(2013) Lipoamide channel-binding sulfonamides selectively inhibit mycobacterial lipoamide dehydrogenase. Biochemistry. 52, 9375-84
(2013) Mechanism for activation of mutated epidermal growth factor receptors in lung cancer. Proc Natl Acad Sci U S A. 110, E3595-604
(2013) Mechanism for KRIT1 release of ICAP1-mediated suppression of integrin activation. Mol Cell. 49, 719-29
(2013) Molecular mechanism of quinone signaling mediated through S-quinonization of a YodB family repressor QsrR. Proc Natl Acad Sci U S A. 110, 5010-5
(2013) Molecular mechanism of quinone signaling mediated through S-quinonization of a YodB family repressor QsrR. Proc Natl Acad Sci U S A. 110, 5010-5
(2013) Native chemical ligation at Asx-Cys, Glx-Cys: chemical synthesis and high-resolution X-ray structure of ShK toxin by racemic protein crystallography. J Am Chem Soc. 135, 11911-9
(2013) Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids. Nature. 500, 463-7
(2013) Nucleotide binding and conformational switching in the hexameric ring of a AAA+ machine. Cell. 153, 628-39
(2013) Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of σ70 domain 1.1.. Proc Natl Acad Sci U S A. 110, 19772-7
(2013) Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of σ70 domain 1.1.. Proc Natl Acad Sci U S A. 110, 19772-7
(2013) A possible role for the asymmetric C-terminal domain dimer of Rous sarcoma virus integrase in viral DNA binding. PLoS One. 8, e56892
(2013) RAC1P29S is a spontaneously activating cancer-associated GTPase. Proc Natl Acad Sci U S A. 110, 912-7
(2013) Replication of a carcinogenic nitropyrene DNA lesion by human Y-family DNA polymerase. Nucleic Acids Res. 41, 2060-71
(2013) On the reproducibility of protein crystal structures: five atomic resolution structures of trypsin. Acta Crystallogr D Biol Crystallogr. 69, 1447-62