Publications
Structurally distinct bacterial TBC-like GAPs link Arf GTPase to Rab1 inactivation to counteract host defenses. Cell. 150, 1029-41
(2012) (2012) (2012) Structure of a calcium-dependent 11R-lipoxygenase suggests a mechanism for Ca2+ regulation. J Biol Chem. 287, 22377-86
(2012) Structure of a force-conveying cadherin bond essential for inner-ear mechanotransduction. Nature. 492, 128-32
(2012) Structure of a glomulin-RBX1-CUL1 complex: inhibition of a RING E3 ligase through masking of its E2-binding surface. Mol Cell. 47, 371-82
(2012) The structure of human GALNS reveals the molecular basis for mucopolysaccharidosis IV A. J Mol Biol. 423, 736-51
(2012) Structure of RPE65 isomerase in a lipidic matrix reveals roles for phospholipids and iron in catalysis. Proc Natl Acad Sci U S A. 109, E2747-56
(2012) Structure of RPE65 isomerase in a lipidic matrix reveals roles for phospholipids and iron in catalysis. Proc Natl Acad Sci U S A. 109, E2747-56
(2012) Structure of the surface layer of the methanogenic archaean Methanosarcina acetivorans. Proc Natl Acad Sci U S A. 109, 11812-7
(2012) Structure-based mechanistic insights into DNMT1-mediated maintenance DNA methylation. Science. 335, 709-12
(2012) Substrate-Selective Inhibition of Cyclooxygenase-2: Development and Evaluation of Achiral Profen Probes. ACS Med Chem Lett. 3, 759-763
(2012) Synthesis, structure, and metalation of two new highly porous zirconium metal-organic frameworks. Inorg Chem. 51, 6443-5
(2012) Tangled up in knots: structures of inactivated forms of E. coli class Ia ribonucleotide reductase. Structure. 20, 1374-83
(2012) Thiamin pyrimidine biosynthesis in Candida albicans : a remarkable reaction between histidine and pyridoxal phosphate. J Am Chem Soc. 134, 9157-9
(2012) (2012) (2012) Type II p21-activated kinases (PAKs) are regulated by an autoinhibitory pseudosubstrate. Proc Natl Acad Sci U S A. 109, 16107-12
(2012) Unexpected fold in the circumsporozoite protein target of malaria vaccines. Proc Natl Acad Sci U S A. 109, 7817-22
(2012) Unexpected fold in the circumsporozoite protein target of malaria vaccines. Proc Natl Acad Sci U S A. 109, 7817-22
(2012) (2012) (2011)
An approach to crystallizing proteins by metal-mediated synthetic symmetrization. Protein Sci. 20, 1876-90
(2011) An approach to crystallizing proteins by metal-mediated synthetic symmetrization. Protein Sci. 20, 1876-90
(2011) (2011)