Publications

Found 1065 results
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2014
Sheng, G., Zhao, H., Wang, J., Rao, Y., Tian, W., Swarts, D. C., van der Oost, J., Patel, D. J., and Wang, Y. (2014) Structure-based cleavage mechanism of Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage. Proc Natl Acad Sci U S A. 111, 652-7
Sheng, G., Zhao, H., Wang, J., Rao, Y., Tian, W., Swarts, D. C., van der Oost, J., Patel, D. J., and Wang, Y. (2014) Structure-based cleavage mechanism of Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage. Proc Natl Acad Sci U S A. 111, 652-7
Huo, Y., Nam, K. Hyun, Ding, F., Lee, H., Wu, L., Xiao, Y., M Farchione, D., Zhou, S., Rajashankar, K., Kurinov, I., Zhang, R., and Ke, A. (2014) Structures of CRISPR Cas3 offer mechanistic insights into Cascade-activated DNA unwinding and degradation. Nat Struct Mol Biol. 21, 771-7
Warner, K. Deigan, Homan, P., Weeks, K. M., Smith, A. G., Abell, C., and Ferré-D'Amaré, A. R. (2014) Validating fragment-based drug discovery for biological RNAs: lead fragments bind and remodel the TPP riboswitch specifically. Chem Biol. 21, 591-5
Warner, K. Deigan, Homan, P., Weeks, K. M., Smith, A. G., Abell, C., and Ferré-D'Amaré, A. R. (2014) Validating fragment-based drug discovery for biological RNAs: lead fragments bind and remodel the TPP riboswitch specifically. Chem Biol. 21, 591-5
2013
Xia, S., Wood, M., Bradley, M. J., De La Cruz, E. M., and Konigsberg, W. H. (2013) Alteration in the cavity size adjacent to the active site of RB69 DNA polymerase changes its conformational dynamics. Nucleic Acids Res. 41, 9077-89
Wheatley, N. M., Gidaniyan, S. D., Liu, Y., Cascio, D., and Yeates, T. O. (2013) Bacterial microcompartment shells of diverse functional types possess pentameric vertex proteins. Protein Sci. 22, 660-5
Demirci, H., Wang, L., Murphy, F. V., Murphy, E. L., Carr, J. F., Blanchard, S. C., Jogl, G., Dahlberg, A. E., and Gregory, S. T. (2013) The central role of protein S12 in organizing the structure of the decoding site of the ribosome. RNA. 19, 1791-801
Sethi, D. K., Gordo, S., Schubert, D. A., and Wucherpfennig, K. W. (2013) Crossreactivity of a human autoimmune TCR is dominated by a single TCR loop. Nat Commun. 4, 2623
Ritacco, C. J., Kamtekar, S., Wang, J., and Steitz, T. A. (2013) Crystal structure of an intermediate of rotating dimers within the synaptic tetramer of the G-segment invertase. Nucleic Acids Res. 41, 2673-82
Li, Y., Wang, J., Kanai, R., and Modis, Y. (2013) Crystal structure of glycoprotein E2 from bovine viral diarrhea virus. Proc Natl Acad Sci U S A. 110, 6805-10
Gao, P., Ascano, M., Wu, Y., Barchet, W., Gaffney, B. L., Zillinger, T., Serganov, A. A., Liu, Y., Jones, R. A., Hartmann, G., Tuschl, T., and Patel, D. J. (2013) Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase. Cell. 153, 1094-107
Xia, S., Wang, J., and Konigsberg, W. H. (2013) DNA mismatch synthesis complexes provide insights into base selectivity of a B family DNA polymerase. J Am Chem Soc. 135, 193-202
Yu, Y., Zhu, J., Huang, P. - S., Wang, J. -huai, Pullen, N., and Springer, T. A. (2013) Domain 1 of mucosal addressin cell adhesion molecule has an I1-set fold and a flexible integrin-binding loop. J Biol Chem. 288, 6284-94
Windsor, M. A., Valk, P. L., Xu, S., Banerjee, S., and Marnett, L. J. (2013) Exploring the molecular determinants of substrate-selective inhibition of cyclooxygenase-2 by lumiracoxib. Bioorg Med Chem Lett. 23, 5860-4
Avital-Shmilovici, M., Mandal, K., Gates, Z. P., Phillips, N. B., Weiss, M. A., and Kent, S. B. H. (2013) Fully convergent chemical synthesis of ester insulin: determination of the high resolution X-ray structure by racemic protein crystallography. J Am Chem Soc. 135, 3173-85
McCarthy, K. R., Schmidt, A. G., Kirmaier, A., Wyand, A. L., Newman, R. M., and Johnson, W. E. (2013) Gain-of-sensitivity mutations in a Trim5-resistant primary isolate of pathogenic SIV identify two independent conserved determinants of Trim5α specificity.. PLoS Pathog. 9, e1003352
Wang, F., Li, G., Altaf, M., Lu, C., Currie, M. A., Johnson, A., and Moazed, D. (2013) Heterochromatin protein Sir3 induces contacts between the amino terminus of histone H4 and nucleosomal DNA. Proc Natl Acad Sci U S A. 110, 8495-500
Bryk, R., Arango, N., Maksymiuk, C., Balakrishnan, A., Wu, Y. - T., Wong, C. - H., Masquelin, T., Hipskind, P., Lima, C. D., and Nathan, C. (2013) Lipoamide channel-binding sulfonamides selectively inhibit mycobacterial lipoamide dehydrogenase. Biochemistry. 52, 9375-84
Bryk, R., Arango, N., Maksymiuk, C., Balakrishnan, A., Wu, Y. - T., Wong, C. - H., Masquelin, T., Hipskind, P., Lima, C. D., and Nathan, C. (2013) Lipoamide channel-binding sulfonamides selectively inhibit mycobacterial lipoamide dehydrogenase. Biochemistry. 52, 9375-84
Ji, X., Wu, Y., Yan, J., Mehrens, J., Yang, H., DeLucia, M., Hao, C., Gronenborn, A. M., Skowronski, J., Ahn, J., and Xiong, Y. (2013) Mechanism of allosteric activation of SAMHD1 by dGTP. Nat Struct Mol Biol. 20, 1304-9
Yin, Q., Sester, D. P., Tian, Y., Hsiao, Y. - S., Lu, A., Cridland, J. A., Sagulenko, V., Thygesen, S. J., Choubey, D., Hornung, V., Walz, T., Stacey, K. J., and Wu, H. (2013) Molecular mechanism for p202-mediated specific inhibition of AIM2 inflammasome activation. Cell Rep. 4, 327-39
Yin, Q., Sester, D. P., Tian, Y., Hsiao, Y. - S., Lu, A., Cridland, J. A., Sagulenko, V., Thygesen, S. J., Choubey, D., Hornung, V., Walz, T., Stacey, K. J., and Wu, H. (2013) Molecular mechanism for p202-mediated specific inhibition of AIM2 inflammasome activation. Cell Rep. 4, 327-39
Simanshu, D. K., Kamlekar, R. Kanth, Wijesinghe, D. S., Zou, X., Zhai, X., Mishra, S. K., Molotkovsky, J. G., Malinina, L., Hinchcliffe, E. H., Chalfant, C. E., Brown, R. E., and Patel, D. J. (2013) Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids. Nature. 500, 463-7
Chen, Q., Sun, X., Zhou, X. -hong, Liu, J. -huan, Wu, J., Zhang, Y., and Wang, J. -huai (2013) N-terminal horseshoe conformation of DCC is functionally required for axon guidance and might be shared by other neural receptors. J Cell Sci. 126, 186-95

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