Publications

Found 4 results
Filters: First Letter Of Last Name is G and Author is Geffken, Ezekiel A  [Clear All Filters]
2025
Boeszoermenyi, A., Radeva, D. L., Schindler, S., Valadares, V., Das, K. M. Padmanab, Dubey, A., Viennet, T., Schmitt, M., Kast, P., Gelev, V. M., Stoyanov, N., Burdzhiev, N., Petrov, O., Ficarro, S., Marto, J., Geffken, E. A., Dhe-Paganon, S., Seo, H. - S., Alexander, N. D., Cooley, R. B., Mehl, R. A., Kovacs, H., Anklin, C., Bermel, W., Kuprov, I., Takeuchi, K., and Arthanari, H. (2025) Leveraging relaxation-optimized H-C correlations in 4-F-phenylalanine as atomic beacons for probing structure and dynamics of large proteins. Nat Chem. 17, 835-846
2022
Johnson, C. W., Seo, H. - S., Terrell, E. M., Yang, M. - H., KleinJan, F., Gebregiworgis, T., Gasmi-Seabrook, G. M. C., Geffken, E. A., Lakhani, J., Song, K., Bashyal, P., Popow, O., Paulo, J. A., Liu, A., Mattos, C., Marshall, C. B., Ikura, M., Morrison, D. K., Dhe-Paganon, S., and Haigis, K. M. (2022) Regulation of GTPase function by autophosphorylation. Mol Cell. 82, 950-968.e14
2021
Dubiella, C., Pinch, B. J., Koikawa, K., Zaidman, D., Poon, E., Manz, T. D., Nabet, B., He, S., Resnick, E., Rogel, A., Langer, E. M., Daniel, C. J., Seo, H. - S., Chen, Y., Adelmant, G., Sharifzadeh, S., Ficarro, S. B., Jamin, Y., da Costa, B. Martins, Zimmerman, M. W., Lian, X., Kibe, S., Kozono, S., Doctor, Z. M., Browne, C. M., Yang, A., Stoler-Barak, L., Shah, R. B., Vangos, N. E., Geffken, E. A., Oren, R., Koide, E., Sidi, S., Shulman, Z., Wang, C., Marto, J. A., Dhe-Paganon, S., Look, T., Zhou, X. Zhen, Lu, K. Ping, Sears, R. C., Chesler, L., Gray, N. S., and London, N. (2021) Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo. Nat Chem Biol. 10.1038/s41589-021-00786-7
2020
Pinch, B. J., Doctor, Z. M., Nabet, B., Browne, C. M., Seo, H. - S., Mohardt, M. L., Kozono, S., Lian, X., Manz, T. D., Chun, Y., Kibe, S., Zaidman, D., Daitchman, D., Yeoh, Z. C., Vangos, N. E., Geffken, E. A., Tan, L., Ficarro, S. B., London, N., Marto, J. A., Buratowski, S., Dhe-Paganon, S., Zhou, X. Zhen, Lu, K. Ping, and Gray, N. S. (2020) Identification of a potent and selective covalent Pin1 inhibitor. Nat Chem Biol. 16, 979-987