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The group II intron maturase: a reverse transcriptase and splicing factor go hand in hand. Curr Opin Struct Biol. 47, 30-39
(2017) Mechanism of differential Zika and dengue virus neutralization by a public antibody lineage targeting the DIII lateral ridge. J Exp Med. 10.1084/jem.20191792
(2020) Structural insights into 5' flap DNA unwinding and incision by the human FAN1 dimer. Nat Commun. 5, 5726
(2014) (2008) Crystal structure of group II intron domain 1 reveals a template for RNA assembly. Nat Chem Biol. 11, 967-72
(2015) (2017) Crystal structures of a group II intron maturase reveal a missing link in spliceosome evolution. Nat Struct Mol Biol. 23, 558-65
(2016) (2023) (2023) The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes. Nat Commun. 5, 2987
(2014) The Lipid A 1-Phosphatase, LpxE, Functionally Connects Multiple Layers of Bacterial Envelope Biogenesis. MBio. 10.1128/mBio.00886-19
(2019) Preclinical safety and efficacy characterization of an LpxC inhibitor against Gram-negative pathogens. Sci Transl Med. 15, eadf5668
(2023) Structures of segments of α-synuclein fused to maltose-binding protein suggest intermediate states during amyloid formation.. Protein Sci. 20, 996-1004
(2011) (2018) PAK4 crystal structures suggest unusual kinase conformational movements. Biochim Biophys Acta. 10.1016/j.bbapap.2017.10.004
(2017) Dramatic improvement of crystals of large RNAs by cation replacement and dehydration. Structure. 22, 1363-71
(2014) Thymine DNA glycosylase specifically recognizes 5-carboxylcytosine-modified DNA. Nat Chem Biol. 8, 328-30
(2012) TrkA undergoes a tetramer-to-dimer conversion to open TrkH which enables changes in membrane potential. Nat Commun. 11, 547
(2020) (2017) The structure of human deoxycytidine kinase in complex with clofarabine reveals key interactions for prodrug activation. Acta Crystallogr D Biol Crystallogr. 62, 133-9
(2006) Molecular pharmacodynamics of emixustat in protection against retinal degeneration. J Clin Invest. 125, 2781-94
(2015) Optimization of Triarylpyridinone Inhibitors of the Main Protease of SARS-CoV-2 to Low-Nanomolar Antiviral Potency. ACS Med Chem Lett. 12, 1325-1332
(2021) Crystal structure of an aminoimidazole riboside kinase from Salmonella enterica: implications for the evolution of the ribokinase superfamily. Structure. 12, 1809-21
(2004) System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes. Mol Cell. 62, 121-36
(2016) (2005)