Publications
Gating mechanisms of acid-sensing ion channels. Nature. 10.1038/nature25782
(2018) Gating mechanisms of acid-sensing ion channels. Nature. 10.1038/nature25782
(2018) GlcNAc-1-P-transferase-tunicamycin complex structure reveals basis for inhibition of N-glycosylation. Nat Struct Mol Biol. 10.1038/s41594-018-0031-y
(2018) GlcNAc-1-P-transferase-tunicamycin complex structure reveals basis for inhibition of N-glycosylation. Nat Struct Mol Biol. 10.1038/s41594-018-0031-y
(2018) Membrane Protein Structure in Live Cells: Methodology for Studying Drug Interaction by Mass Spectrometry-Based Footprinting. Biochemistry. 57, 286-294
(2018) Microfocus diffraction from different regions of a protein crystal: structural variations and unit-cell polymorphism. Acta Crystallogr D Struct Biol. 74, 411-421
(2018) Molecular mechanism of a covalent allosteric inhibitor of SUMO E1 activating enzyme. Nat Commun. 9, 5145
(2018) (2018) Piperidinyl Ureas Chemically Control Defective in Cullin Neddylation 1 (DCN1)-Mediated Cullin Neddylation. J Med Chem. 61, 2680-2693
(2018) Stabilization of warfarin-binding pocket of VKORC1 and VKORL1 by a peripheral region determines their different sensitivity to warfarin inhibition. J Thromb Haemost. 16, 1164-1175
(2018) Strategic Approaches to Overcome Resistance against Gram-Negative Pathogens Using β-Lactamase Inhibitors and β-Lactam Enhancers: Activity of Three Novel Diazabicyclooctanes WCK 5153, Zidebactam (WCK 5107), and WCK 4234.. J Med Chem. 61, 4067-4086
(2018) (2018) Structural basis for potent and broad inhibition of HIV-1 RT by thiophene[3,2-]pyrimidine non-nucleoside inhibitors. Elife. 10.7554/eLife.36340
(2018) Structural basis for recognition of human 7SK long noncoding RNA by the La-related protein Larp7. Proc Natl Acad Sci U S A. 115, E6457-E6466
(2018) Structural basis for usher activation and intramolecular subunit transfer in P pilus biogenesis in Escherichia coli. Nat Microbiol. 10.1038/s41564-018-0255-y
(2018) Structural insights into drug development strategy targeting EGFR T790M/C797S. Oncotarget. 9, 13652-13665
(2018) Structural insights into drug development strategy targeting EGFR T790M/C797S. Oncotarget. 9, 13652-13665
(2018) Structural insights into drug development strategy targeting EGFR T790M/C797S. Oncotarget. 9, 13652-13665
(2018) Structural insights into drug development strategy targeting EGFR T790M/C797S. Oncotarget. 9, 13652-13665
(2018) Structural insights into drug development strategy targeting EGFR T790M/C797S. Oncotarget. 9, 13652-13665
(2018) Structural Insights into Oxygen-Dependent Signal Transduction within Globin Coupled Sensors. Inorg Chem. 57, 14386-14395
(2018) T4 DNA ligase structure reveals a prototypical ATP-dependent ligase with a unique mode of sliding clamp interaction. Nucleic Acids Res. 10.1093/nar/gky776
(2018) The AAA+ ATPase TRIP13 remodels HORMA domains through N-terminal engagement and unfolding. EMBO J. 10.15252/embj.201797291
(2017) (2017) (2017)