Publications

Found 133 results
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2016
Uppalapati, M., Lee, D. Jun, Mandal, K., Li, H., Miranda, L. P., Lowitz, J., Kenney, J., Adams, J. J., Ault-Riché, D., Kent, S. B. H., and Sidhu, S. S. (2016) A Potent d-Protein Antagonist of VEGF-A is Nonimmunogenic, Metabolically Stable, and Longer-Circulating in Vivo. ACS Chem Biol. 11, 1058-65
Eram, M. S., Shen, Y., Szewczyk, M., Wu, H., Senisterra, G., Li, F., Butler, K. V., H Kaniskan, Ü., Speed, B. A., Seña, Cdela, Dong, A., Zeng, H., Schapira, M., Brown, P. J., Arrowsmith, C. H., Barsyte-Lovejoy, D., Liu, J., Vedadi, M., and Jin, J. (2016) A Potent, Selective, and Cell-Active Inhibitor of Human Type I Protein Arginine Methyltransferases. ACS Chem Biol. 11, 772-781
Schormann, N., Zhukovskaya, N., Bedwell, G., Nuth, M., Gillilan, R., Prevelige, P. E., Ricciardi, R. P., Banerjee, S., and Chattopadhyay, D. (2016) Poxvirus uracil-DNA glycosylase-An unusual member of the family I uracil-DNA glycosylases. Protein Sci. 25, 2113-2131
Dippel, A. B., Olenginski, G. M., Maurici, N., Liskov, M. T., Brewer, S. H., and Phillips-Piro, C. M. (2016) Probing the effectiveness of spectroscopic reporter unnatural amino acids: a structural study. Acta Crystallogr D Struct Biol. 72, 121-30
Chen, M., Chou, W. K. W., Al-Lami, N., Faraldos, J. A., Allemann, R. K., Cane, D. E., and Christianson, D. W. (2016) Probing the Role of Active Site Water in the Sesquiterpene Cyclization Reaction Catalyzed by Aristolochene Synthase. Biochemistry. 55, 2864-74
Wang, Y., Roose, B. W., Philbin, J. P., Doman, J. L., and Dmochowski, I. J. (2016) Programming A Molecular Relay for Ultrasensitive Biodetection through (129)Xe NMR.. Angew Chem Int Ed Engl. 55, 1733-6
Kim, K. - H., Ko, D. - K., Kim, Y. - T., Kim, N. Hyeong, Paul, J., Zhang, S. - Q., Murray, C. B., Acharya, R., DeGrado, W. F., Kim, Y. Ho, and Grigoryan, G. (2016) Protein-directed self-assembly of a fullerene crystal. Nat Commun. 7, 11429
2015
Zhang, J., and Ferré-D'Amaré, A. R. (2015) Post-crystallization Improvement of RNA Crystal Diffraction Quality. Methods Mol Biol. 1316, 13-24
Lai, Y. - T., Jiang, L., Chen, W., and Yeates, T. O. (2015) On the predictability of the orientation of protein domains joined by a spanning alpha-helical linker. Protein Eng Des Sel. 28, 491-9
Englert, M., Nakamura, A., Wang, Y. - S., Eiler, D., Söll, D., and Guo, L. - T. (2015) Probing the active site tryptophan of Staphylococcus aureus thioredoxin with an analog. Nucleic Acids Res. 43, 11061-7
Saoji, M., Zhang, D., and Paukstelis, P. J. (2015) Probing the role of sequence in the assembly of three-dimensional DNA crystals. Biopolymers. 103, 618-26
Mateja, A., Paduch, M., Chang, H. - Y., Szydlowska, A., Kossiakoff, A. A., Hegde, R. S., and Keenan, R. J. (2015) Protein targeting. Structure of the Get3 targeting factor in complex with its membrane protein cargo. Science. 347, 1152-5
Chen, S., Yang, Z., Wilkinson, A. W., Deshpande, A. J., Sidoli, S., Krajewski, K., Strahl, B. D., Garcia, B. A., Armstrong, S. A., Patel, D. J., and Gozani, O. (2015) The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79. Mol Cell. 60, 319-27
2014
Tao, Z., Fusco, A., Bin Huang, D. -, Gupta, K., Kim, D. Young, Ware, C. F., Van Duyne, G. D., and Ghosh, G. (2014) p100/IκBδ sequesters and inhibits NF-κB through kappaBsome formation.. Proc Natl Acad Sci U S A. 111, 15946-51
Seo, M., and Lee, Y. - H. (2014) PFKFB3 regulates oxidative stress homeostasis via its S-glutathionylation in cancer. J Mol Biol. 426, 830-42
Tian, Y., Simanshu, D. K., Ma, J. - B., Park, J. - E., Heo, I., V Kim, N., and Patel, D. J. (2014) A phosphate-binding pocket within the platform-PAZ-connector helix cassette of human Dicer. Mol Cell. 53, 606-16
Luo, Z., Dauter, M., and Dauter, Z. (2014) Phosphates in the Z-DNA dodecamer are flexible, but their P-SAD signal is sufficient for structure solution. Acta Crystallogr D Biol Crystallogr. 70, 1790-800
Piatkevich, K. D., English, B. P., Malashkevich, V. N., Xiao, H., Almo, S. C., Singer, R. H., and Verkhusha, V. V. (2014) Photoswitchable red fluorescent protein with a large Stokes shift. Chem Biol. 21, 1402-14
Brohawn, S. G., Campbell, E. B., and MacKinnon, R. (2014) Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel. Nature. 516, 126-30
Guo, L. - T., Wang, Y. - S., Nakamura, A., Eiler, D., Kavran, J. M., Wong, M., Kiessling, L. L., Steitz, T. A., O'Donoghue, P., and Söll, D. (2014) Polyspecific pyrrolysyl-tRNA synthetases from directed evolution. Proc Natl Acad Sci U S A. 111, 16724-9
Sawaya, M. R., Cascio, D., Gingery, M., Rodriguez, J., Goldschmidt, L., Colletier, J. - P., Messerschmidt, M. M., Boutet, S., Koglin, J. E., Williams, G. J., Brewster, A. S., Nass, K., Hattne, J., Botha, S., R Doak, B., Shoeman, R. L., DePonte, D. P., Park, H. - W., Federici, B. A., Sauter, N. K., Schlichting, I., and Eisenberg, D. S. (2014) Protein crystal structure obtained at 2.9 Å resolution from injecting bacterial cells into an X-ray free-electron laser beam.. Proc Natl Acad Sci U S A. 111, 12769-74
Zhou, L., Bosscher, M., Zhang, C., Ozçubukçu, S., Zhang, L., Zhang, W., Li, C. J., Liu, J., Jensen, M. P., Lai, L., and He, C. (2014) A protein engineered to bind uranyl selectively and with femtomolar affinity. Nat Chem. 6, 236-41
Kolli, N., and Garman, S. C. (2014) Proteolytic activation of human cathepsin A. J Biol Chem. 289, 11592-600
Polikanov, Y. S., Steitz, T. A., and C Innis, A. (2014) A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome. Nat Struct Mol Biol. 21, 787-93
2013
Nguyen, J. B., Pool, C. D., Wong, C. Y. B., Treger, R. S., Williams, D. L., Cappello, M., Lea, W. A., Simeonov, A., Vermeire, J. J., and Modis, Y. (2013) Peroxiredoxin-1 from the human hookworm Ancylostoma ceylanicum forms a stable oxidized decamer and is covalently inhibited by conoidin A. Chem Biol. 20, 991-1001

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