Publications
(2017) (2019)
Synthesis of macrocyclic nucleoside antibacterials and their interactions with MraY. Nat Commun. 13, 7575
(2022) Structures of human ENT1 in complex with adenosine reuptake inhibitors. Nat Struct Mol Biol. 26, 599-606
(2019) Structural insights into inhibition of lipid I production in bacterial cell wall synthesis. Nature. 533, 557-560
(2016) Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters. Elife. 3, e03604
(2014) Structural analyses of Ca²⁺/CaM interaction with NaV channel C-termini reveal mechanisms of calcium-dependent regulation.. Nat Commun. 5, 4896
(2014) GlcNAc-1-P-transferase-tunicamycin complex structure reveals basis for inhibition of N-glycosylation. Nat Struct Mol Biol. 10.1038/s41594-018-0031-y
(2018) Crystal structure of the ternary complex of a NaV C-terminal domain, a fibroblast growth factor homologous factor, and calmodulin. Structure. 20, 1167-76
(2012) Crystal structure of the MOP flippase MurJ in an inward-facing conformation. Nat Struct Mol Biol. 24, 171-176
(2017) Crystal structure of MraY, an essential membrane enzyme for bacterial cell wall synthesis. Science. 341, 1012-1016
(2013) Crystal structure of a concentrative nucleoside transporter from Vibrio cholerae at 2.4 Å.. Nature. 483, 489-93
(2012) Conformational plasticity in the selectivity filter of the TRPV2 ion channel. Nat Struct Mol Biol. 25, 405-415
(2018) Chemical logic of MraY inhibition by antibacterial nucleoside natural products. Nat Commun. 10, 2917
(2019)