Found 11 results
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Xia, S., Wang, J., and Konigsberg, W. H. (2013) DNA mismatch synthesis complexes provide insights into base selectivity of a B family DNA polymerase. J Am Chem Soc. 135, 193-202
Xia, S., Wood, M., Bradley, M. J., De La Cruz, E. M., and Konigsberg, W. H. (2013) Alteration in the cavity size adjacent to the active site of RB69 DNA polymerase changes its conformational dynamics. Nucleic Acids Res. 41, 9077-89
Xia, S., and Konigsberg, W. H. (2014) Mispairs with Watson-Crick base-pair geometry observed in ternary complexes of an RB69 DNA polymerase variant. Protein Sci. 23, 508-13
Xia, S., Eom, S. Hyun, Konigsberg, W. H., and Wang, J. (2012) Structural basis for differential insertion kinetics of dNMPs opposite a difluorotoluene nucleotide residue. Biochemistry. 51, 1476-85
Xia, S., Eom, S. Hyun, Konigsberg, W. H., and Wang, J. (2012) Bidentate and tridentate metal-ion coordination states within ternary complexes of RB69 DNA polymerase. Protein Sci. 21, 447-51
Xia, S., Beckman, J., Wang, J., and Konigsberg, W. H. (2012) Using a fluorescent cytosine analogue tC(o) to probe the effect of the Y567 to Ala substitution on the preinsertion steps of dNMP incorporation by RB69 DNA polymerase. Biochemistry. 51, 4609-17
Xia, S., Christian, T. D., Wang, J., and Konigsberg, W. H. (2012) Probing minor groove hydrogen bonding interactions between RB69 DNA polymerase and DNA. Biochemistry. 51, 4343-53
Xia, S., Vashishtha, A., Bulkley, D., Eom, S. Hyun, Wang, J., and Konigsberg, W. H. (2012) Contribution of partial charge interactions and base stacking to the efficiency of primer extension at and beyond abasic sites in DNA. Biochemistry. 51, 4922-31
Xia, S., Konigsberg, W. H., and Wang, J. (2011) Hydrogen-bonding capability of a templating difluorotoluene nucleotide residue in an RB69 DNA polymerase ternary complex. J Am Chem Soc. 133, 10003-5
Xia, S., Wang, M., Blaha, G., Konigsberg, W. H., and Wang, J. (2011) Structural insights into complete metal ion coordination from ternary complexes of B family RB69 DNA polymerase. Biochemistry. 50, 9114-24
Xia, S., Wang, M., Lee, H. R., Sinha, A., Blaha, G., Christian, T., Wang, J., and Konigsberg, W. (2011) Variation in mutation rates caused by RB69pol fidelity mutants can be rationalized on the basis of their kinetic behavior and crystal structures. J Mol Biol. 406, 558-70