Publications
ykkC riboswitches employ an add-on helix to adjust specificity for polyanionic ligands. Nat Chem Biol. 14, 887-894
(2018) Subsite Ligand Recognition and Cooperativity in the TPP Riboswitch: Implications for Fragment-Linking in RNA Ligand Discovery. ACS Chem Biol. 17, 438-448
(2022) (2014) Structural insights into amino acid binding and gene control by a lysine riboswitch. Nature. 455, 1263-7
(2008) Structural and kinetic insights into stimulation of RppH-dependent RNA degradation by the metabolic enzyme DapF. Nucleic Acids Res. 10.1093/nar/gky327
(2018) Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch. Cell Rep. 13, 1800-13
(2015) (2022) Principles of RNA and nucleotide discrimination by the RNA processing enzyme RppH. Nucleic Acids Res. 10.1093/nar/gkaa024
(2020) Long-range pseudoknot interactions dictate the regulatory response in the tetrahydrofolate riboswitch. Proc Natl Acad Sci U S A. 108, 14801-6
(2011) Inhibitors of bacterial HS biogenesis targeting antibiotic resistance and tolerance. Science. 372, 1169-1175
(2021) A distinct RNA recognition mechanism governs Np decapping by RppH. Proc Natl Acad Sci U S A. 10.1073/pnas.2117318119
(2022) Crystal structure reveals specific recognition of a G-quadruplex RNA by a β-turn in the RGG motif of FMRP.. Proc Natl Acad Sci U S A. 112, E5391-400
(2015) (2009)