Publications
Mechanisms of SARS-CoV-2 neutralization by shark variable new antigen receptors elucidated through X-ray crystallography. Nat Commun. 12, 7325
(2021) Mechanistic and structural analyses of the role of His67 in the yeast polyamine oxidase Fms1. Biochemistry. 51, 4888-97
(2012) Mechanistic and structural analyses of the roles of active site residues in yeast polyamine oxidase Fms1: characterization of the N195A and D94N enzymes. Biochemistry. 51, 8690-7
(2012) (2022) Mechanistic manifold in a hemoprotein-catalyzed cyclopropanation reaction with diazoketone. Nat Commun. 14, 7985
(2023) Metal dependence and branched RNA cocrystal structures of the RNA lariat debranching enzyme Dbr1. Proc Natl Acad Sci U S A. 113, 14727-14732
(2016) (2022) (2021) A Mini-Twister Variant and Impact of Residues/Cations on the Phosphodiester Cleavage of this Ribozyme Class. Angew Chem Int Ed Engl. 54, 15128-15133
(2015) A Mitochondria-Targeting SIRT3 Inhibitor with Activity against Diffuse Large B Cell Lymphoma. J Med Chem. 67, 15428-15437
(2024) MOB1 Mediated Phospho-recognition in the Core Mammalian Hippo Pathway. Mol Cell Proteomics. 16, 1098-1110
(2017) Molecular basis for allosteric specificity regulation in class Ia ribonucleotide reductase from Escherichia coli. Elife. 5, e07141
(2016) (2011) (2021) Molecular Basis of C-N Bond Cleavage by the Glycyl Radical Enzyme Choline Trimethylamine-Lyase. Cell Chem Biol. 23, 1206-1216
(2016) Molecular basis of hemoglobin binding and heme removal in Corynebacterium diphtheriae. Proc Natl Acad Sci U S A. 122, e2411833122
(2025) Molecular Bidents with Two Electrophilic Warheads as a New Pharmacological Modality. ACS Cent Sci. 10, 1156-1166
(2024) Molecular level insights into thermally induced α-chymotrypsinogen A amyloid aggregation mechanism and semiflexible protofibril morphology.. Biochemistry. 49, 10553-64
(2010) Molecular mechanism for NLRP6 inflammasome assembly and activation. Proc Natl Acad Sci U S A. 10.1073/pnas.1817221116
(2019) (2014) Molecular principles of Piwi-mediated cotranscriptional silencing through the dimeric SFiNX complex. Genes Dev. 35, 392-409
(2021) MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a. Nat Commun. 2, 533
(2011) MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a. Nat Commun. 2, 533
(2011) (2017) Mutations in PBP2 from Ceftriaxone-resistant Neisseria gonorrhoeae Alter the Dynamics of the β3-β4 Loop to Favor a Low-affinity Drug-binding State.. J Biol Chem. 10.1016/j.jbc.2021.101188
(2021)