Publications
Found 972 results
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(2013) Structure of the Chlamydia trachomatis immunodominant antigen Pgp3. J Biol Chem. 288, 22068-79
(2016) Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition. Nucleic Acids Res. 44, 2439-50
(2012) Structural basis for the rescue of stalled ribosomes: structure of YaeJ bound to the ribosome. Science. 335, 1370-2
(2014) Structures of benzylsuccinate synthase elucidate roles of accessory subunits in glycyl radical enzyme activation and activity. Proc Natl Acad Sci U S A. 111, 10161-6
(2015) Structural Studies of Radical Enzymes in Bacterial Central Metabolism. Ph.D. thesis, Massachusetts Institute of Technology, Cambridge, Massachusetts
(2022) Structural Studies and Structure Activity Relationships for Novel Computationally Designed Non-nucleoside Inhibitors and Their Interactions With HIV-1 Reverse Transcriptase. Front Mol Biosci. 9, 805187
(2011) Structural and kinetic insights into the mechanism of 5-hydroxyisourate hydrolase from Klebsiella pneumoniae. Acta Crystallogr D Biol Crystallogr. 67, 671-7
(2010) Structural and mechanistic studies on Klebsiella pneumoniae 2-Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase. J Biol Chem. 285, 35446-54
(2022) Structure and activity of human TMPRSS2 protease implicated in SARS-CoV-2 activation. Nat Chem Biol. 10.1038/s41589-022-01059-7
(2024) Simultaneous enhancement of multiple functional properties using evolution-informed protein design. Nat Commun. 15, 5141
(2023) Simultaneous enhancement of multiple functional properties using evolution-informed protein design. bioRxiv. 10.1101/2023.05.09.539914
(2022) Structures and function of a tailoring oxidase in complex with a nonribosomal peptide synthetase module. Nat Commun. 13, 548
(2011) Synthetic symmetrization in the crystallization and structure determination of CelA from Thermotoga maritima. Protein Sci. 20, 168-78
(2018) Specific covalent inhibition of MALT1 paracaspase suppresses B cell lymphoma growth. J Clin Invest. 128, 4397-4412
(2015) Structural basis for the disruption of the cerebral cavernous malformations 2 (CCM2) interaction with Krev interaction trapped 1 (KRIT1) by disease-associated mutations. J Biol Chem. 290, 2842-53
(2015) Structure and vascular function of MEKK3-cerebral cavernous malformations 2 complex. Nat Commun. 6, 7937
(2013) Structural studies of cerebral cavernous malformations 2 (CCM2) reveal a folded helical domain at its C-terminus. FEBS Lett. 587, 272-7
(2017) Structural studies of viperin, an antiviral radical SAM enzyme. Proc Natl Acad Sci U S A. 10.1073/pnas.1705402114
(2020) Structural Basis of the Substrate Selectivity of Viperin. Biochemistry. 10.1021/acs.biochem.9b00741
(2010) Structure of a eukaryotic CLC transporter defines an intermediate state in the transport cycle. Science. 330, 635-41
(2019) Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase from . Biochemistry. 58, 5011-5021
(2014) Structure and function of REP34 implicates carboxypeptidase activity in Francisella tularensis host cell invasion. J Biol Chem. 289, 30668-30679

