Publications

Found 1154 results
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Journal Article
Deochand, D. K., Perera, I. C., Crochet, R. B., Gilbert, N. C., Newcomer, M. E., and Grove, A. (2016) Histidine switch controlling pH-dependent protein folding and DNA binding in a transcription factor at the core of synthetic network devices. Mol Biosyst. 12, 2417-26
Eduful, B. J., O'Byrne, S. N., Temme, L., Asquith, C. R. M., Liang, Y., Picado, A., Pilotte, J. R., Hossain, M. Anwar, Wells, C. I., Zuercher, W. J., Catta-Preta, C. M. C., Ramos, P. Zonzini, Santiago, Ade S., Couñago, R. M., Langendorf, C. G., Nay, K., Oakhill, J. S., Pulliam, T. L., Lin, C., Awad, D., Willson, T. M., Frigo, D. E., Scott, J. W., and Drewry, D. H. (2021) Hinge Binder Scaffold Hopping Identifies Potent Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2) Inhibitor Chemotypes. J Med Chem. 64, 10849-10877
Gnann, A. D., Xia, Y., Soule, J., Barthélemy, C., Mawani, J. S., Musoke, S. Nzikoba, Castellano, B. M., Brignole, E. J., Frueh, D. P., and Dowling, D. P. (2022) High-resolution structures of a siderophore-producing cyclization domain from Yersinia pestis offer a refined proposal of substrate binding. J Biol Chem. 298, 102454
Svetlov, M. S., Plessa, E., Chen, C. - W., Bougas, A., Krokidis, M. G., Dinos, G. P., and Polikanov, Y. (2019) High-resolution crystal structures of ribosome-bound chloramphenicol and erythromycin provide the ultimate basis for their competition. RNA. 10.1261/rna.069260.118
Zeqiraj, E., Tian, L., Piggott, C. A., Pillon, M. C., Duffy, N. M., Ceccarelli, D. F., Keszei, A. F. A., Lorenzen, K., Kurinov, I., Orlicky, S., Gish, G. D., Heck, A. J. R., Guarné, A., Greenberg, R. A., and Sicheri, F. (2015) Higher-Order Assembly of BRCC36-KIAA0157 Is Required for DUB Activity and Biological Function. Mol Cell. 59, 970-83
Policarpo, R. L., Decultot, L., May, E., Kuzmič, P., Carlson, S., Huang, D., Chu, V., Wright, B. A., Dhakshinamoorthy, S., Kannt, A., Rani, S., Dittakavi, S., Panarese, J. D., Gaudet, R., and Shair, M. D. (2019) High-Affinity Alkynyl Bisubstrate Inhibitors of Nicotinamide -Methyltransferase (NNMT). J Med Chem. 10.1021/acs.jmedchem.9b01238
Policarpo, R. L., Decultot, L., May, E., Kuzmič, P., Carlson, S., Huang, D., Chu, V., Wright, B. A., Dhakshinamoorthy, S., Kannt, A., Rani, S., Dittakavi, S., Panarese, J. D., Gaudet, R., and Shair, M. D. (2019) High-Affinity Alkynyl Bisubstrate Inhibitors of Nicotinamide -Methyltransferase (NNMT). J Med Chem. 10.1021/acs.jmedchem.9b01238
Policarpo, R. L., Decultot, L., May, E., Kuzmič, P., Carlson, S., Huang, D., Chu, V., Wright, B. A., Dhakshinamoorthy, S., Kannt, A., Rani, S., Dittakavi, S., Panarese, J. D., Gaudet, R., and Shair, M. D. (2019) High-Affinity Alkynyl Bisubstrate Inhibitors of Nicotinamide -Methyltransferase (NNMT). J Med Chem. 10.1021/acs.jmedchem.9b01238
Brzezinski, K., Brzuszkiewicz, A., Dauter, M., Kubicki, M., Jaskolski, M., and Dauter, Z. (2011) High regularity of Z-DNA revealed by ultra high-resolution crystal structure at 0.55 A. Nucleic Acids Res. 39, 6238-48
Brzezinski, K., Brzuszkiewicz, A., Dauter, M., Kubicki, M., Jaskolski, M., and Dauter, Z. (2011) High regularity of Z-DNA revealed by ultra high-resolution crystal structure at 0.55 A. Nucleic Acids Res. 39, 6238-48
Garcha, H. Kaur, Nawar, N., Sorger, H., Erdogan, F., Aung, M. Myat Khine, Sedighi, A., Manaswiyoungkul, P., Seo, H. - S., Schönefeldt, S., Pölöske, D., Dhe-Paganon, S., Neubauer, H. A., Mustjoki, S. M., Herling, M., de Araujo, E. D., Moriggl, R., and Gunning, P. T. (2022) High Efficacy and Drug Synergy of HDAC6-Selective Inhibitor NN-429 in Natural Killer (NK)/T-Cell Lymphoma. Pharmaceuticals (Basel). 10.3390/ph15111321
Garcha, H. Kaur, Nawar, N., Sorger, H., Erdogan, F., Aung, M. Myat Khine, Sedighi, A., Manaswiyoungkul, P., Seo, H. - S., Schönefeldt, S., Pölöske, D., Dhe-Paganon, S., Neubauer, H. A., Mustjoki, S. M., Herling, M., de Araujo, E. D., Moriggl, R., and Gunning, P. T. (2022) High Efficacy and Drug Synergy of HDAC6-Selective Inhibitor NN-429 in Natural Killer (NK)/T-Cell Lymphoma. Pharmaceuticals (Basel). 10.3390/ph15111321
Phillips, A. M., Maurer, D. P., Brooks, C., Dupic, T., Schmidt, A. G., and Desai, M. M. (2023) Hierarchical sequence-affinity landscapes shape the evolution of breadth in an anti-influenza receptor binding site antibody. Elife. 10.7554/eLife.83628
Phillips, A. M., Maurer, D. P., Brooks, C., Dupic, T., Schmidt, A. G., and Desai, M. M. (2023) Hierarchical sequence-affinity landscapes shape the evolution of breadth in an anti-influenza receptor binding site antibody. Elife. 10.7554/eLife.83628
Sue, A. C. - H., Mannige, R. V., Deng, H., Cao, D., Wang, C., Gándara, F., J Stoddart, F., Whitelam, S., and Yaghi, O. M. (2015) Heterogeneity of functional groups in a metal-organic framework displays magic number ratios. Proc Natl Acad Sci U S A. 112, 5591-6
Abhishek, S., Deeksha, W., and Rajakumara, E. (2021) Helical and β-Turn Conformations in the Peptide Recognition Regions of the VIM1 PHD Finger Abrogate H3K4 Peptide Recognition.. Biochemistry. 10.1021/acs.biochem.1c00191
Bridwell-Rabb, J., Kang, G., Zhong, A., Liu, H. -wen, and Drennan, C. L. (2016) An HD domain phosphohydrolase active site tailored for oxetanocin-A biosynthesis. Proc Natl Acad Sci U S A. 113, 13750-13755
Deo, C., Abdelfattah, A. S., Bhargava, H. K., Berro, A. J., Falco, N., Farrants, H., Moeyaert, B., Chupanova, M., Lavis, L. D., and Schreiter, E. R. (2021) The HaloTag as a general scaffold for far-red tunable chemigenetic indicators. Nat Chem Biol. 17, 718-723
An, L., Hicks, D. R., Zorine, D., Dauparas, J., Wicky, B. I. M., Milles, L. F., Courbet, A., Bera, A. K., Nguyen, H., Kang, A., Carter, L., and Baker, D. (2023) Hallucination of closed repeat proteins containing central pockets. Nat Struct Mol Biol. 30, 1755-1760
Wicky, B. I. M., Milles, L. F., Courbet, A., Ragotte, R. J., Dauparas, J., Kinfu, E., Tipps, S., Kibler, R. D., Baek, M., DiMaio, F., Li, X., Carter, L., Kang, A., Nguyen, H., Bera, A. K., and Baker, D. (2022) Hallucinating symmetric protein assemblies. Science. 378, 56-61
Wicky, B. I. M., Milles, L. F., Courbet, A., Ragotte, R. J., Dauparas, J., Kinfu, E., Tipps, S., Kibler, R. D., Baek, M., DiMaio, F., Li, X., Carter, L., Kang, A., Nguyen, H., Bera, A. K., and Baker, D. (2022) Hallucinating symmetric protein assemblies. Science. 378, 56-61
Wang, G. G., Song, J., Wang, Z., Dormann, H. L., Casadio, F., Li, H., Luo, J. - L., Patel, D. J., and C Allis, D. (2009) Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger. Nature. 459, 847-51
Mehta, R. S., Mayers, J. R., Zhang, Y., Bhosle, A., Glasser, N. R., Nguyen, L. H., Ma, W., Bae, S., Branck, T., Song, K., Sebastian, L., Pacheco, J. Avila, Seo, H. - S., Clish, C., Dhe-Paganon, S., Ananthakrishnan, A. N., Franzosa, E. A., Balskus, E. P., Chan, A. T., and Huttenhower, C. (2023) Gut microbial metabolism of 5-ASA diminishes its clinical efficacy in inflammatory bowel disease. Nat Med. 29, 700-709
Mieher, J. L., Larson, M. R., Schormann, N., Purushotham, S., Wu, R., Rajashankar, K. R., Wu, H., and Deivanayagam, C. (2018) Glucan Binding Protein C of Mediates both Sucrose-Independent and Sucrose-Dependent Adherence. Infect Immun. 10.1128/IAI.00146-18
Carrell, C. J., Ma, J. K., Antholine, W. E., Hosler, J. P., F Mathews, S., and Davidson, V. L. (2007) Generation of novel copper sites by mutation of the axial ligand of amicyanin. Atomic resolution structures and spectroscopic properties. Biochemistry. 46, 1900-12

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