Publications
A distributed residue network permits conformational binding specificity in a conserved family of actin remodelers. Elife. 10.7554/eLife.70601
(2021) Divalent cation and chloride ion sites of chicken acid sensing ion channel 1a elucidated by x-ray crystallography. PLoS One. 13, e0202134
(2018) Diverse array of neutralizing antibodies elicited upon Spike Ferritin Nanoparticle vaccination in rhesus macaques. Nat Commun. 15, 200
(2024) DNA aptamers against the DUX4 protein reveal novel therapeutic implications for FSHD. FASEB J. 34, 4573-4590
(2020) DNA asymmetry promotes SUMO modification of the single-stranded DNA-binding protein RPA. EMBO J. 10.15252/embj.2019103787
(2021) A DNA G-quadruplex/i-motif hybrid. Nucleic Acids Res. 10.1093/nar/gkz1008
(2019) DNA mismatch synthesis complexes provide insights into base selectivity of a B family DNA polymerase. J Am Chem Soc. 135, 193-202
(2013) DNA repair. Mechanism of DNA interstrand cross-link processing by repair nuclease FAN1. Science. 346, 1127-30
(2014) DNA Sequence Determinants Controlling Affinity, Stability and Shape of DNA Complexes Bound by the Nucleoid Protein Fis. PLoS One. 11, e0150189
(2016) DNA sequence-dependent activity and base flipping mechanisms of DNMT1 regulate genome-wide DNA methylation. Nat Commun. 11, 3723
(2020) Dna2 nuclease-helicase structure, mechanism and regulation by Rpa. Elife. 10.7554/eLife.09832
(2015) DNA3'pp5'G de-capping activity of aprataxin: effect of cap nucleoside analogs and structural basis for guanosine recognition. Nucleic Acids Res. 43, 6075-83
(2015) DNAJB8 oligomerization is mediated by an aromatic-rich motif that is dispensable for substrate activity. Structure. 32, 662-678.e8
(2024) DNAJB8 oligomerization is mediated by an aromatic-rich motif that is dispensable for substrate activity. bioRxiv. 10.1101/2023.03.06.531355
(2023) (2021) Dodecameric structure of a small heat shock protein from Mycobacterium marinum M. Proteins. 10.1002/prot.25657
(2019) Domain 1 of mucosal addressin cell adhesion molecule has an I1-set fold and a flexible integrin-binding loop. J Biol Chem. 288, 6284-94
(2013) Domain alternation and active site remodeling are conserved structural features of ubiquitin E1. J Biol Chem. 292, 12089-12099
(2017) A domain insertion in Escherichia coli GyrB adopts a novel fold that plays a critical role in gyrase function. Nucleic Acids Res. 38, 7830-44
(2010) Domain Movements upon Activation of Phenylalanine Hydroxylase Characterized by Crystallography and Chromatography-Coupled Small-Angle X-ray Scattering. J Am Chem Soc. 138, 6506-16
(2016) Domain organization in Candida glabrata THI6, a bifunctional enzyme required for thiamin biosynthesis in eukaryotes. Biochemistry. 49, 9922-34
(2010) Dominant Rio1 kinase/ATPase catalytic mutant induces trapping of late pre-40S biogenesis factors in 80S-like ribosomes. Nucleic Acids Res. 42, 8635-47
(2014) Dramatic improvement of crystals of large RNAs by cation replacement and dehydration. Structure. 22, 1363-71
(2014) DRUG DEVELOPMENT. Phthalimide conjugation as a strategy for in vivo target protein degradation. Science. 348, 1376-81
(2015) Dual arginine recognition of LRRK2 phosphorylated Rab GTPases. Biophys J. 10.1016/j.bpj.2021.03.030
(2021)