Publications

Found 1144 results
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2022
Dumitrescu, D. G., Gordon, E. M., Kovalyova, Y., Seminara, A. B., Duncan-Lowey, B., Forster, E. R., Zhou, W., Booth, C. J., Shen, A., Kranzusch, P. J., and Hatzios, S. K. (2022) A microbial transporter of the dietary antioxidant ergothioneine. Cell. 185, 4526-4540.e18
Dumitrescu, D. G., Gordon, E. M., Kovalyova, Y., Seminara, A. B., Duncan-Lowey, B., Forster, E. R., Zhou, W., Booth, C. J., Shen, A., Kranzusch, P. J., and Hatzios, S. K. (2022) A microbial transporter of the dietary antioxidant ergothioneine. Cell. 185, 4526-4540.e18
Beyett, T. S., To, C., Heppner, D. E., Rana, J. K., Schmoker, A. M., Jang, J., De Clercq, D. J. H., Gomez, G., Scott, D. A., Gray, N. S., Jänne, P. A., and Eck, M. J. (2022) Molecular basis for cooperative binding and synergy of ATP-site and allosteric EGFR inhibitors. Nat Commun. 13, 2530
Greisman, J. B., Dalton, K. M., Sheehan, C. J., Klureza, M. A., Kurinov, I., and Hekstra, D. R. (2022) Native SAD phasing at room temperature. Acta Crystallogr D Struct Biol. 78, 986-996
Thorsen, M. K., Draganova, E. B., and Heldwein, E. E. (2022) The nuclear egress complex of Epstein-Barr virus buds membranes through an oligomerization-driven mechanism. PLoS Pathog. 18, e1010623
Andreev, V. I., Yu, C., Wang, J., Schnabl, J., Tirian, L., Gehre, M., Handler, D., Duchek, P., Novatchkova, M., Baumgartner, L., Meixner, K., Sienski, G., Patel, D. J., and Brennecke, J. (2022) Panoramix SUMOylation on chromatin connects the piRNA pathway to the cellular heterochromatin machinery. Nat Struct Mol Biol. 29, 130-142
Wang, Y., Tsitsiklis, A., Devoe, S., Gao, W., H Chu, H., Zhang, Y., Li, W., Wong, W. Ki, Deane, C. M., Neau, D., Slansky, J. E., Thomas, P. G., Robey, E. A., and Dai, S. (2022) Peptide Centric Vβ Specific Germline Contacts Shape a Specialist T Cell Response.. Front Immunol. 13, 847092
Wang, Y., Tsitsiklis, A., Devoe, S., Gao, W., H Chu, H., Zhang, Y., Li, W., Wong, W. Ki, Deane, C. M., Neau, D., Slansky, J. E., Thomas, P. G., Robey, E. A., and Dai, S. (2022) Peptide Centric Vβ Specific Germline Contacts Shape a Specialist T Cell Response.. Front Immunol. 13, 847092
Wang, Y., Tsitsiklis, A., Devoe, S., Gao, W., H Chu, H., Zhang, Y., Li, W., Wong, W. Ki, Deane, C. M., Neau, D., Slansky, J. E., Thomas, P. G., Robey, E. A., and Dai, S. (2022) Peptide Centric Vβ Specific Germline Contacts Shape a Specialist T Cell Response.. Front Immunol. 13, 847092
Reglero, C., Dieck, C. L., Zask, A., Forouhar, F., Laurent, A. P., Lin, W. - H. W., Albero, R., Miller, H. I., Ma, C., Gastier-Foster, J. M., Loh, M. L., Tong, L., Stockwell, B. R., Palomero, T., and Ferrando, A. A. (2022) Pharmacological inhibition of NT5C2 reverses genetic and non-genetic drivers of 6-MP resistance in acute lymphoblastic leukemia. Cancer Discov. 10.1158/2159-8290.CD-22-0010
Schiltz, C. J., Wilson, J. R., Hosford, C. J., Adams, M. C., Preising, S. E., DeBlasio, S. L., MacLeod, H. J., Van Eck, J., Heck, M. L., and Chappie, J. S. (2022) Polerovirus N-terminal readthrough domain structures reveal molecular strategies for mitigating virus transmission by aphids. Nat Commun. 13, 6368
Wang, Z., Dang, H. V., Amaya, M., Xu, Y., Yin, R., Yan, L., Hickey, A. C., Annand, E. J., Horsburgh, B. A., Reid, P. A., Smith, I., Eden, J. - S., Xu, K., Broder, C. C., and Veesler, D. (2022) Potent monoclonal antibody-mediated neutralization of a divergent Hendra virus variant. Proc Natl Acad Sci U S A. 119, e2122769119
Zuk, A., Si, Z., Loi, S., Bommegowda, S., Hoivik, D., Danthi, S., Molnar, G., Csizmadia, V., and Rabinowitz, M. (2022) Preclinical characterization of vadadustat (AKB-6548), an oral small molecule hypoxia inducible factor prolyl-4-hydroxylase inhibitor, for the potential treatment of renal anemia. J Pharmacol Exp Ther. 10.1124/jpet.122.001126
Arrigoni, C., Lolicato, M., Shaya, D., Rohaim, A., Findeisen, F., Fong, L. - K., Colleran, C. M., Dominik, P., Kim, S. S., Schuermann, J. P., DeGrado, W. F., Grabe, M., Kossiakoff, A. A., and Minor, D. L. (2022) Quaternary structure independent folding of voltage-gated ion channel pore domain subunits. Nat Struct Mol Biol. 29, 537-548
Arrigoni, C., Lolicato, M., Shaya, D., Rohaim, A., Findeisen, F., Fong, L. - K., Colleran, C. M., Dominik, P., Kim, S. S., Schuermann, J. P., DeGrado, W. F., Grabe, M., Kossiakoff, A. A., and Minor, D. L. (2022) Quaternary structure independent folding of voltage-gated ion channel pore domain subunits. Nat Struct Mol Biol. 29, 537-548
Hauser, B. M., Sangesland, M., St Denis, K. J., Lam, E. C., Case, J. Brett, Windsor, I. W., Feldman, J., Caradonna, T. M., Kannegieter, T., Diamond, M. S., Balazs, A. B., Lingwood, D., and Schmidt, A. G. (2022) Rationally designed immunogens enable immune focusing following SARS-CoV-2 spike imprinting. Cell Rep. 38, 110561
Johnson, C. W., Seo, H. - S., Terrell, E. M., Yang, M. - H., KleinJan, F., Gebregiworgis, T., Gasmi-Seabrook, G. M. C., Geffken, E. A., Lakhani, J., Song, K., Bashyal, P., Popow, O., Paulo, J. A., Liu, A., Mattos, C., Marshall, C. B., Ikura, M., Morrison, D. K., Dhe-Paganon, S., and Haigis, K. M. (2022) Regulation of GTPase function by autophosphorylation. Mol Cell. 82, 950-968.e14
Czajka, T. F., Vance, D. J., Davis, S., Rudolph, M. J., and Mantis, N. J. (2022) Single-domain antibodies neutralize ricin toxin intracellularly by blocking access to ribosomal P-stalk proteins. J Biol Chem. 298, 101742
Prew, M. S., Camara, C. M., Botzanowski, T., Moroco, J. A., Bloch, N. B., Levy, H. R., Seo, H. - S., Dhe-Paganon, S., Bird, G. H., Herce, H. D., Gygi, M. A., Escudero, S., Wales, T. E., Engen, J. R., and Walensky, L. D. (2022) Structural basis for defective membrane targeting of mutant enzyme in human VLCAD deficiency. Nat Commun. 13, 3669
Krochmal, D., Shao, Y., Li, N. - S., DasGupta, S., Shelke, S. A., Koirala, D., and Piccirilli, J. A. (2022) Structural basis for substrate binding and catalysis by a self-alkylating ribozyme. Nat Chem Biol. 10.1038/s41589-021-00950-z
Kumar, S., Zavaliev, R., Wu, Q., Zhou, Y., Cheng, J., Dillard, L., Powers, J., Withers, J., Zhao, J., Guan, Z., Borgnia, M. J., Bartesaghi, A., Dong, X., and Zhou, P. (2022) Structural basis of NPR1 in activating plant immunity. Nature. 605, 561-566
Kumar, S., Zavaliev, R., Wu, Q., Zhou, Y., Cheng, J., Dillard, L., Powers, J., Withers, J., Zhao, J., Guan, Z., Borgnia, M. J., Bartesaghi, A., Dong, X., and Zhou, P. (2022) Structural basis of NPR1 in activating plant immunity. Nature. 605, 561-566
Luo, M., Zhou, B., Reddem, E. R., Tang, B., Chen, B., Zhou, R., Liu, H., Liu, L., Katsamba, P. S., Au, K. - K., Man, H. - O., To, K. Kai- Wang, Yuen, K. - Y., Shapiro, L., Dang, S., Ho, D. D., and Chen, Z. (2022) Structural insights into broadly neutralizing antibodies against SARS-CoV-2 elicited by hybrid immunity. Emerg Microbes Infect. 10.1080/22221751.2022.2146538
Chen, B., Basak, S., Chen, P., Zhang, C., Perry, K., Tian, S., Yu, C., Dong, M., Huang, L., Bowen, M. E., and Jin, R. (2022) Structure and conformational dynamics of toxin A. Life Sci Alliance. 10.26508/lsa.202201383
Moeller, N. H., Shi, K., Demir, Ö., Belica, C., Banerjee, S., Yin, L., Durfee, C., Amaro, R. E., and Aihara, H. (2022) Structure and dynamics of SARS-CoV-2 proofreading exoribonuclease ExoN. Proc Natl Acad Sci U S A. 10.1073/pnas.2106379119

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