Glucose-neopentyl glycol (GNG) amphiphiles for membrane protein study.

Publication Type:

Journal Article

Source:

Chem Commun (Camb), Volume 49, Issue 23, p.2287-9 (2013)

Keywords:

Detergents, Glucose, Glycols, Membrane Proteins, Protein Stability, Rhodobacter capsulatus

Abstract:

<p>The development of a new class of surfactants for membrane protein manipulation, "GNG amphiphiles", is reported. These amphiphiles display promising behavior for membrane proteins, as demonstrated recently by the high resolution structure of a sodium-pumping pyrophosphatase reported by Kellosalo et al. (Science, 2012, 337, 473).</p>

Beamline: 
24-ID-C