COVID-19 Research

NECAT is giving priority to COVID-19 research while accepting all GUP beamtime requests.

EIGER2 X Detector Repairs

At the start up of operations for the 2021-2 run, it was discovered that one of the cards which aggregates data from multiple modules in the EIGER2 detector on 24-ID-C was faulty.  As a result, NE-CAT was forced to reschedule all users on 24-ID-C for the first week of user operations.  However, Dectris was able to immediately send us a replacement part which was successfully installed by Ed Lynch, Jim Withrow, and Malcolm Capel.  Replacing the card did require removal of the EIGER2 from the 24-ID-C A-frame and its subsequent re-installation.

Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite.

Modular basis for potent SARS-CoV-2 neutralization by a prevalent VH1-2-derived antibody class.

Office Hours

Questions?

....Answers Provided.

 

Zoom-based office hours to answer questions regarding using NE-CAT, data processing, structure solution or anything else x-ray crystallography-related available weekly.

Thursday, 1:00 - 3:00 PM Central Time

Request the Zoom link via email.

SARS-CoV-2 evolution in an immunocompromised host reveals shared neutralization escape mechanisms.

Activity profiling and crystal structures of inhibitor-bound SARS-CoV-2 papain-like protease: A framework for anti-COVID-19 drug design.