Publications

Found 1676 results
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2017
Taylor, A. B., Roberts, K. M., Cao, X., Clark, N. E., Holloway, S. P., Donati, E., Polcaro, C. M., Pica-Mattoccia, L., Tarpley, R. S., McHardy, S. F., Cioli, D., LoVerde, P. T., Fitzpatrick, P. F., and P Hart, J. (2017) Structural and enzymatic insights into species-specific resistance to schistosome parasite drug therapy. J Biol Chem. 292, 11154-11164
Hirschi, M. Marianne (2017) Structural and Functional Studies of Nucleoside Transporters. Ph.D. thesis, Duke University, Durham, North Carolina
Hoelper, D., Huang, H., Jain, A. Y., Patel, D. J., and Lewis, P. W. (2017) Structural and mechanistic insights into ATRX-dependent and -independent functions of the histone chaperone DAXX. Nat Commun. 8, 1193
Peng, G., Yang, Y., Pasquarella, J. R., Xu, L., Qian, Z., Holmes, K. V., and Li, F. (2017) Structural and Molecular Evidence Suggesting Coronavirus-driven Evolution of Mouse Receptor. J Biol Chem. 292, 2174-2181
Kudalkar, S. N., Beloor, J., Chan, A. H., Lee, W. - G., Jorgensen, W. L., Kumar, P., and Anderson, K. S. (2017) Structural and Preclinical Studies of Computationally Designed Non-Nucleoside Reverse Transcriptase Inhibitors for Treating HIV infection. Mol Pharmacol. 91, 383-391
Ramagopal, U. A., Liu, W., Garrett-Thomson, S. C., Bonanno, J. B., Yan, Q., Srinivasan, M., Wong, S. C., Bell, A., Mankikar, S., Rangan, V. S., Deshpande, S., Korman, A. J., and Almo, S. C. (2017) Structural basis for cancer immunotherapy by the first-in-class checkpoint inhibitor ipilimumab. Proc Natl Acad Sci U S A. 114, E4223-E4232
Su, M., Gao, F., Yuan, Q., Mao, Y., Li, D. - L., Guo, Y., Yang, C., Wang, X. - H., Bruni, R., Kloss, B., Zhao, H., Zeng, Y., Ben Zhang, F. -, Marks, A. R., Hendrickson, W. A., and Chen, Y. - H. (2017) Structural basis for conductance through TRIC cation channels. Nat Commun. 8, 15103
Trachman, R. J., Demeshkina, N. A., Lau, M. W. L., Panchapakesan, S. Shyam S., C Y Jeng, S., Unrau, P. J., and Ferré-D'Amaré, A. R. (2017) Structural basis for high-affinity fluorophore binding and activation by RNA Mango. Nat Chem Biol. 13, 807-813
Liu, B., and Steitz, T. A. (2017) Structural insights into NusG regulating transcription elongation. Nucleic Acids Res. 45, 968-974
Li, Y., Zhao, Y., Su, M., Glover, K., Chakravarthy, S., Colbert, C. L., Levine, B., and Sinha, S. C. (2017) Structural insights into the interaction of the conserved mammalian proteins GAPR-1 and Beclin 1, a key autophagy protein. Acta Crystallogr D Struct Biol. 73, 775-792
Li, Y., Zhao, Y., Su, M., Glover, K., Chakravarthy, S., Colbert, C. L., Levine, B., and Sinha, S. C. (2017) Structural insights into the interaction of the conserved mammalian proteins GAPR-1 and Beclin 1, a key autophagy protein. Acta Crystallogr D Struct Biol. 73, 775-792
Yuan, L., Lv, Z., Atkison, J. H., and Olsen, S. K. (2017) Structural insights into the mechanism and E2 specificity of the RBR E3 ubiquitin ligase HHARI. Nat Commun. 8, 211
Hubin, E. A., Lilic, M., Darst, S. A., and Campbell, E. A. (2017) Structural insights into the mycobacteria transcription initiation complex from analysis of X-ray crystal structures. Nat Commun. 8, 16072
Fenwick, M. K., Li, Y., Cresswell, P., Modis, Y., and Ealick, S. E. (2017) Structural studies of viperin, an antiviral radical SAM enzyme. Proc Natl Acad Sci U S A. 10.1073/pnas.1705402114
Montemayor, E. J., Didychuk, A. L., Liao, H., Hu, P., Brow, D. A., and Butcher, S. E. (2017) Structure and conformational plasticity of the U6 small nuclear ribonucleoprotein core. Acta Crystallogr D Struct Biol. 73, 1-8
Wasmuth, E. V., Zinder, J. C., Zattas, D., Das, M., and Lima, C. D. (2017) Structure and reconstitution of yeast Mpp6-nuclear exosome complexes reveals that Mpp6 stimulates RNA decay and recruits the Mtr4 helicase. Elife. 10.7554/eLife.29062
McMillan, B. J., Zimmerman, B., Egan, E. D., Lofgren, M., Xu, X., Hesser, A., and Blacklow, S. C. (2017) Structure of human POFUT1, its requirement in ligand-independent oncogenic Notch signaling, and functional effects of Dowling-Degos mutations. Glycobiology. 10.1093/glycob/cwx020
Cook, J. D., Sultana, A., and Lee, J. E. (2017) Structure of the infectious salmon anemia virus receptor complex illustrates a unique binding strategy for attachment. Proc Natl Acad Sci U S A. 114, E2929-E2936
Xiong, Y., Li, F., Babault, N., Wu, H., Dong, A., Zeng, H., Chen, X., Arrowsmith, C. H., Brown, P. J., Liu, J., Vedadi, M., and Jin, J. (2017) Structure-activity relationship studies of G9a-like protein (GLP) inhibitors. Bioorg Med Chem. 25, 4414-4423
Xiong, Y., Li, F., Babault, N., Wu, H., Dong, A., Zeng, H., Chen, X., Arrowsmith, C. H., Brown, P. J., Liu, J., Vedadi, M., and Jin, J. (2017) Structure-activity relationship studies of G9a-like protein (GLP) inhibitors. Bioorg Med Chem. 25, 4414-4423
Lanier, M., Pickens, J., Bigi, S. V., Bradshaw-Pierce, E. L., Chambers, A., Cheruvallath, Z. S., Cole, D., Dougan, D. R., Ermolieff, J., Gibson, T., Halkowycz, P., Hirokawa, A., Ivetac, A., Miura, J., Nunez, E., Sabat, M., Tyhonas, J., Wang, H., Wang, X., and Swann, S. (2017) Structure-Based Design of ASK1 Inhibitors as Potential Agents for Heart Failure. ACS Med Chem Lett. 8, 316-320
Lamberto, I., Liu, X., Seo, H. - S., Schauer, N. J., Iacob, R. E., Hu, W., Das, D., Mikhailova, T., Weisberg, E. L., Engen, J. R., Anderson, K. C., Chauhan, D., Dhe-Paganon, S., and Buhrlage, S. J. (2017) Structure-Guided Development of a Potent and Selective Non-covalent Active-Site Inhibitor of USP7. Cell Chem Biol. 10.1016/j.chembiol.2017.09.003
Lamberto, I., Liu, X., Seo, H. - S., Schauer, N. J., Iacob, R. E., Hu, W., Das, D., Mikhailova, T., Weisberg, E. L., Engen, J. R., Anderson, K. C., Chauhan, D., Dhe-Paganon, S., and Buhrlage, S. J. (2017) Structure-Guided Development of a Potent and Selective Non-covalent Active-Site Inhibitor of USP7. Cell Chem Biol. 10.1016/j.chembiol.2017.09.003
Su, C. - C., Yin, L., Kumar, N., Dai, L., Radhakrishnan, A., Bolla, J. Reddy, Lei, H. - T., Chou, T. - H., Delmar, J. A., Rajashankar, K. R., Zhang, Q., Shin, Y. - K., and Yu, E. W. (2017) Structures and transport dynamics of a Campylobacter jejuni multidrug efflux pump. Nat Commun. 8, 171
Didychuk, A. L., Montemayor, E. J., Carrocci, T. J., DeLaitsch, A. T., Lucarelli, S. E., Westler, W. M., Brow, D. A., Hoskins, A. A., and Butcher, S. E. (2017) Usb1 controls U6 snRNP assembly through evolutionarily divergent cyclic phosphodiesterase activities. Nat Commun. 8, 497

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