Publications

Found 284 results
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2025
Ota, N., Davies, C. W., Kang, J., Yan, D., Scherl, A., Wong, A., Cook, R., Tao, X., Dunlap, D., Klabunde, S., Mantik, P., Mohanan, V., Lin, W. Y., McBride, J., Sadekar, S., Storek, K. M., Lupardus, P., Ye, Z., Wallweber, H. Ackerly, Kiefer, J. R., Xu, M., Chan, P., Nagapudi, K., Yi, T., and Koerber, J. T. (2025) Engineering a protease-stable, oral single-domain antibody to inhibit IL-23 signaling. Proc Natl Acad Sci U S A. 122, e2501635122
Clyde-Allen, E., Zmudzinski, M., Afsar, M., James, C., Nayak, A., Nayak, D., Bury, P. Dos Santos, Jochmans, D., Neyts, J., Scott, C. J., Olsen, S. K., Drag, M., and Williams, R. (2025) Identification and Exploration of a Series of SARS-Cov‑2 M Cyano-Based Inhibitors Revealing Ortho-Substitution Effects within the P3 Biphenyl Group.. ACS Med Chem Lett. 16, 1935-1945
Olaoye, O. O., Erdogan, F., Gracia-Hernandez, M., Garcha, H. Kaur, Sedighi, A., Ashraf, Q. F., Nawar, N., Geletu, M., Seo, H. - S., Abdallah, D. I., Abdeldayem, A., Hassan, M. Murtaza, Dhe-Paganon, S., de Araujo, E. D., Villagra, A., and Gunning, P. T. (2025) Improved Pharmacokinetic Profiles of HDAC6 Inhibitors via Cap Group Modifications. J Med Chem. 10.1021/acs.jmedchem.5c00479
Garg, A., On, K. Fan, Xiao, Y., Elkayam, E., Cifani, P., David, Y., and Joshua-Tor, L. (2025) The molecular basis of Human FN3K mediated phosphorylation of glycated substrates. Nat Commun. 16, 941
Schwartze, T. A., Morosky, S. A., Rosato, T. L., Henrickson, A., Lin, G., Hinck, C. S., Taylor, A. B., Olsen, S. K., Calero, G., Demeler, B., Roman, B. L., and Hinck, A. P. (2025) Molecular Basis of Interchain Disulfide Bond Formation in BMP-9 and BMP-10. J Mol Biol. 437, 168935
Terayama, K., Furuzono, S., Fer, N., Yan, W., Young, L. C., Czyzyk, D. J., de Salazar, R. Goldstein, Sasaki, M., Uozumi, A., Konishi, M., Kanda, S., Sogawa, Y., Yamaguchi, M., Tsuji, T., Kuroyanagi, J., Hayashi, M., Ogura, Y., Simanshu, D. K., Kubota, K., Tanaka, J., and McCormick, F. (2025) Molecular glues that facilitate RAS binding to PI3Kα promote glucose uptake without insulin.. Science. 389, 402-408
Ubah, O. C., Lake, E. W., Ott, K. L., Priyanka, S., Celeda, S., West, J. L., Gunaratne, G. S., Shi, K., Moeller, N. H., Porter, A. J., Aihara, H., Kosoff, D., LeBeau, A. M., and Barelle, C. J. (2025) The structural basis for the selective antagonism of soluble TNF-alpha by shark variable new antigen receptors. Nat Commun. 10.1038/s41467-025-66967-3
Yirmiya, E., Hobbs, S. J., Leavitt, A., Osterman, I., Avraham, C., Hochhauser, D., Madhala, B., Skovorodka, M., Tan, J. M. J., Toyoda, H. C., Chebotar, I., Itkin, M., Malitsky, S., Amitai, G., Kranzusch, P. J., and Sorek, R. (2025) Structure-guided discovery of viral proteins that inhibit host immunity. Cell. 10.1016/j.cell.2024.12.035
Sabonis, D., Avraham, C., Chang, R. B., Lu, A., Herbst, E., Silanskas, A., Vilutis, D., Leavitt, A., Yirmiya, E., Toyoda, H. C., Ruksenaite, A., Zaremba, M., Osterman, I., Amitai, G., Kranzusch, P. J., Sorek, R., and Tamulaitiene, G. (2025) TIR domains produce histidine-ADPR as an immune signal in bacteria. Nature. 642, 467-473

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