Publications

Found 835 results
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2024
He, Q., Wang, C., Jain, R., Byrnes, J., Farquhar, E. R., Reed, E., Berezovsky, E., Chance, M. R., Lodowski, D., and An, R. (2024) An engineered lactate oxidase based electrochemical sensor for continuous detection of biomarker lactic acid in human sweat and serum. Heliyon. 10, e34301
Rudolph, M. J., Tsymbal, A. M., Dutta, A., Davis, S. A., Algava, B., Roberge, J. Y., Tumer, N. E., and Li, X. - P. (2024) Fragment Screening to Identify Inhibitors Targeting Ribosome Binding of Shiga Toxin 2. ACS Infect Dis. 10.1021/acsinfecdis.4c00224
Funk, M. A., Zimanyi, C. M., Andree, G. A., Hamilos, A. E., and Drennan, C. L. (2024) How ATP and dATP Act as Molecular Switches to Regulate Enzymatic Activity in the Prototypical Bacterial Class Ia Ribonucleotide Reductase. Biochemistry. 63, 2517-2531
Gallant, J. P., Hicks, D., Shi, K., Moeller, N. H., Hoppe, B., Lake, E. W., Baehr, C., Pravetoni, M., Aihara, H., and LeBeau, A. M. (2024) Identification and biophysical characterization of a novel domain-swapped camelid antibody specific for fentanyl. J Biol Chem. 300, 107502
Yoon, J., Zhang, Y. Meng, Her, C., Grant, R. A., Ponomarenko, A. I., Ackermann, B. E., Hui, T., Lin, Y. - S., Debelouchina, G. T., and Shoulders, M. D. (2024) The immune-evasive proline-283 substitution in influenza nucleoprotein increases aggregation propensity without altering the native structure. Sci Adv. 10, eadl6144
Sun, T., Heiden, J. A. Vander, Gao, X., Yin, J., Uttarwar, S., Liang, W. - C., Jia, G., Yadav, R., Huang, Z., Mitra, M., Halpern, W., Bender, H. S., Brightbill, H. D., Wu, Y., Lupardus, P., Ramalingam, T., and Arron, J. R. (2024) Isoform-selective TGF-β3 inhibition for systemic sclerosis.. Med. 5, 132-147.e7
Zhang, Z., Fu, J., Rack, J. Gregor Mat, Li, C., Voorneveld, J., Filippov, D. V., Ahel, I., Luo, Z. - Q., and Das, C. (2024) Legionella metaeffector MavL reverses ubiquitin ADP-ribosylation via a conserved arginine-specific macrodomain. Nat Commun. 15, 2452
Münzker, L., Kimani, S. W., Fowkes, M. M., Dong, A., Zheng, H., Li, Y., Dasovich, M., Zak, K. M., Leung, A. K. L., Elkins, J. M., Kessler, D., Arrowsmith, C. H., Halabelian, L., and Böttcher, J. (2024) A ligand discovery toolbox for the WWE domain family of human E3 ligases. Commun Biol. 7, 901
Aleksandrova, E. V., Ma, C. - X., Klepacki, D., Alizadeh, F., Vázquez-Laslop, N., Liang, J. - H., Polikanov, Y. S., and Mankin, A. S. (2024) Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms. Nat Chem Biol. 10.1038/s41589-024-01685-3
Aleksandrova, E. V., Ma, C. - X., Klepacki, D., Alizadeh, F., Vázquez-Laslop, N., Liang, J. - H., Polikanov, Y. S., and Mankin, A. S. (2024) Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms. Nat Chem Biol. 10.1038/s41589-024-01685-3
Srivastava, D., Gowribidanur-Chinnaswamy, P., Gaur, P., Spies, M., Swaroop, A., and Artemyev, N. O. (2024) Molecular basis of CRX/DNA recognition and stoichiometry at the Ret4 response element. Structure. 10.1016/j.str.2024.07.004
Anderson, M. J. M., Hayward, A. N., Smiley, A. T., Shi, K., Pawlak, M. R., Aird, E. J., Grant, E., Greenberg, L., Aihara, H., Evans, R. L., Ulens, C., and Gordon, W. R. (2024) Molecular basis of proteolytic cleavage regulation by the extracellular matrix receptor dystroglycan. Structure. 32, 1984-1996.e5
Anderson, M. J. M., Hayward, A. N., Smiley, A. T., Shi, K., Pawlak, M. R., Aird, E. J., Grant, E., Greenberg, L., Aihara, H., Evans, R. L., Ulens, C., and Gordon, W. R. (2024) Molecular basis of proteolytic cleavage regulation by the extracellular matrix receptor dystroglycan. Structure. 32, 1984-1996.e5
Anderson, M. J. M., Hayward, A. N., Smiley, A. T., Shi, K., Pawlak, M. R., Aird, E. J., Grant, E., Greenberg, L., Aihara, H., Evans, R. L., Ulens, C., and Gordon, W. R. (2024) Molecular basis of proteolytic cleavage regulation by the extracellular matrix receptor dystroglycan. Structure. 32, 1984-1996.e5
Gama, F. H. de Souza, Dutra, L. A., Hawgood, M., Reis, C. Vinícius, Serafim, R. A. M., Ferreira, M. A., Teodoro, B. V. M., Takarada, J. Emi, Santiago, A. S., Balourdas, D. - I., Nilsson, A. - S., Urien, B., Almeida, V. M., Gileadi, C., Ramos, P. Z., Salmazo, A., Vasconcelos, S. N. S., Cunha, M. R., Mueller, S., Knapp, S., Massirer, K. B., Elkins, J. M., Gileadi, O., Mascarello, A., Lemmens, B. B. L. G., Guimarães, C. R. W., Azevedo, H., and Couñago, R. M. (2024) Novel Dihydropteridinone Derivatives As Potent Inhibitors of the Understudied Human Kinases Vaccinia-Related Kinase 1 and Casein Kinase 1δ/ε.. J Med Chem. 67, 8609-8629
Gama, F. H. de Souza, Dutra, L. A., Hawgood, M., Reis, C. Vinícius, Serafim, R. A. M., Ferreira, M. A., Teodoro, B. V. M., Takarada, J. Emi, Santiago, A. S., Balourdas, D. - I., Nilsson, A. - S., Urien, B., Almeida, V. M., Gileadi, C., Ramos, P. Z., Salmazo, A., Vasconcelos, S. N. S., Cunha, M. R., Mueller, S., Knapp, S., Massirer, K. B., Elkins, J. M., Gileadi, O., Mascarello, A., Lemmens, B. B. L. G., Guimarães, C. R. W., Azevedo, H., and Couñago, R. M. (2024) Novel Dihydropteridinone Derivatives As Potent Inhibitors of the Understudied Human Kinases Vaccinia-Related Kinase 1 and Casein Kinase 1δ/ε.. J Med Chem. 67, 8609-8629
Yirmiya, E., Leavitt, A., Lu, A., Ragucci, A. E., Avraham, C., Osterman, I., Garb, J., Antine, S. P., Mooney, S. E., Hobbs, S. J., Kranzusch, P. J., Amitai, G., and Sorek, R. (2024) Phages overcome bacterial immunity via diverse anti-defence proteins. Nature. 625, 352-359
Yirmiya, E., Leavitt, A., Lu, A., Ragucci, A. E., Avraham, C., Osterman, I., Garb, J., Antine, S. P., Mooney, S. E., Hobbs, S. J., Kranzusch, P. J., Amitai, G., and Sorek, R. (2024) Phages overcome bacterial immunity via diverse anti-defence proteins. Nature. 625, 352-359
Yirmiya, E., Leavitt, A., Lu, A., Ragucci, A. E., Avraham, C., Osterman, I., Garb, J., Antine, S. P., Mooney, S. E., Hobbs, S. J., Kranzusch, P. J., Amitai, G., and Sorek, R. (2024) Phages overcome bacterial immunity via diverse anti-defence proteins. Nature. 625, 352-359
Wang, H., Cheng, C., Dal Santo, J. L., Shen, C. - H., Bylund, T., Henry, A. R., Howe, C. A., Hwang, J., Morano, N. C., Morris, D. J., Pletnev, S., Roark, R. S., Zhou, T., Hansen, B. T., Hoyt, F. H., Johnston, T. S., Wang, S., Zhang, B., Ambrozak, D. R., Becker, J. E., Bender, M. F., Changela, A., Chaudhary, R., Corcoran, M., Corrigan, A. R., Foulds, K. E., Guo, Y., Lee, M., Li, Y., Lin, B. C., Liu, T., Louder, M. K., Mandolesi, M., Mason, R. D., McKee, K., Nair, V., O'Dell, S., Olia, A. S., Ou, L., Pegu, A., Raju, N., Rawi, R., Roberts-Torres, J., Sarfo, E. K., Sastry, M., Schaub, A. J., Schmidt, S. D., Schramm, C. A., Schwartz, C. L., Smith, S. C., Stephens, T., Stuckey, J., Teng, I. - T., Todd, J. - P., Tsybovsky, Y., Van Wazer, D. J., Wang, S., Doria-Rose, N. A., Fischer, E. R., Georgiev, I. S., Hedestam, G. B. Karlsson, Sheng, Z., Woodward, R. A., Douek, D. C., Koup, R. A., Pierson, T. C., Shapiro, L., Shaw, G. M., Mascola, J. R., and Kwong, P. D. (2024) Potent and broad HIV-1 neutralization in fusion peptide-primed SHIV-infected macaques. Cell. 187, 7214-7231.e23
Radakovic, A., Lewicka, A., Todisco, M., Aitken, H. R. M., Weiss, Z., Kim, S., Bannan, A., Piccirilli, J. A., and Szostak, J. W. (2024) A potential role for RNA aminoacylation prior to its role in peptide synthesis. Proc Natl Acad Sci U S A. 121, e2410206121
Berger, S., Seeger, F., Yu, T. - Y., Aydin, M., Yang, H., Rosenblum, D., Guenin-Macé, L., Glassman, C., Arguinchona, L., Sniezek, C., Blackstone, A., Carter, L., Ravichandran, R., Ahlrichs, M., Murphy, M., Pultz, I. Swanson, Kang, A., Bera, A. K., Stewart, L., K Garcia, C., Naik, S., Spangler, J. B., Beigel, F., Siebeck, M., Gropp, R., and Baker, D. (2024) Preclinical proof of principle for orally delivered Th17 antagonist miniproteins. Cell. 187, 4305-4317.e18
Berger, S., Seeger, F., Yu, T. - Y., Aydin, M., Yang, H., Rosenblum, D., Guenin-Macé, L., Glassman, C., Arguinchona, L., Sniezek, C., Blackstone, A., Carter, L., Ravichandran, R., Ahlrichs, M., Murphy, M., Pultz, I. Swanson, Kang, A., Bera, A. K., Stewart, L., K Garcia, C., Naik, S., Spangler, J. B., Beigel, F., Siebeck, M., Gropp, R., and Baker, D. (2024) Preclinical proof of principle for orally delivered Th17 antagonist miniproteins. Cell. 187, 4305-4317.e18
Berger, S., Seeger, F., Yu, T. - Y., Aydin, M., Yang, H., Rosenblum, D., Guenin-Macé, L., Glassman, C., Arguinchona, L., Sniezek, C., Blackstone, A., Carter, L., Ravichandran, R., Ahlrichs, M., Murphy, M., Pultz, I. Swanson, Kang, A., Bera, A. K., Stewart, L., K Garcia, C., Naik, S., Spangler, J. B., Beigel, F., Siebeck, M., Gropp, R., and Baker, D. (2024) Preclinical proof of principle for orally delivered Th17 antagonist miniproteins. Cell. 187, 4305-4317.e18
Papini, C., Ullah, I., Ranjan, A. P., Zhang, S., Wu, Q., Spasov, K. A., Zhang, C., Mothes, W., Crawford, J. M., Lindenbach, B. D., Uchil, P. D., Kumar, P., Jorgensen, W. L., and Anderson, K. S. (2024) Proof-of-concept studies with a computationally designed M inhibitor as a synergistic combination regimen alternative to Paxlovid. Proc Natl Acad Sci U S A. 121, e2320713121

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