Publications

Found 1653 results
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2024
Berger, S., Seeger, F., Yu, T. - Y., Aydin, M., Yang, H., Rosenblum, D., Guenin-Macé, L., Glassman, C., Arguinchona, L., Sniezek, C., Blackstone, A., Carter, L., Ravichandran, R., Ahlrichs, M., Murphy, M., Pultz, I. Swanson, Kang, A., Bera, A. K., Stewart, L., K Garcia, C., Naik, S., Spangler, J. B., Beigel, F., Siebeck, M., Gropp, R., and Baker, D. (2024) Preclinical proof of principle for orally delivered Th17 antagonist miniproteins. Cell. 187, 4305-4317.e18
Berger, S., Seeger, F., Yu, T. - Y., Aydin, M., Yang, H., Rosenblum, D., Guenin-Macé, L., Glassman, C., Arguinchona, L., Sniezek, C., Blackstone, A., Carter, L., Ravichandran, R., Ahlrichs, M., Murphy, M., Pultz, I. Swanson, Kang, A., Bera, A. K., Stewart, L., K Garcia, C., Naik, S., Spangler, J. B., Beigel, F., Siebeck, M., Gropp, R., and Baker, D. (2024) Preclinical proof of principle for orally delivered Th17 antagonist miniproteins. Cell. 187, 4305-4317.e18
Berger, S., Seeger, F., Yu, T. - Y., Aydin, M., Yang, H., Rosenblum, D., Guenin-Macé, L., Glassman, C., Arguinchona, L., Sniezek, C., Blackstone, A., Carter, L., Ravichandran, R., Ahlrichs, M., Murphy, M., Pultz, I. Swanson, Kang, A., Bera, A. K., Stewart, L., K Garcia, C., Naik, S., Spangler, J. B., Beigel, F., Siebeck, M., Gropp, R., and Baker, D. (2024) Preclinical proof of principle for orally delivered Th17 antagonist miniproteins. Cell. 187, 4305-4317.e18
Shin, H. Esther, Pan, C., Curran, D. M., Bateman, T. J., H Y Chong, D., Ng, D., Shah, M., and Moraes, T. F. (2024) Prevalence of Slam-dependent hemophilins in Gram-negative bacteria. J Bacteriol. 206, e0002724
Hsiao, Y. - C., Wallweber, H. Ackerly, Alberstein, R. G., Lin, Z., Du, C., Etxeberria, A., Aung, T., Shang, Y., Seshasayee, D., Seeger, F., Watkins, A. M., Hansen, D. V., Bohlen, C. J., Hsu, P. L., and Hötzel, I. (2024) Rapid affinity optimization of an anti-TREM2 clinical lead antibody by cross-lineage immune repertoire mining. Nat Commun. 15, 8382
Meeks, K. R., Bogner, A. N., and Tanner, J. J. (2024) Screening a knowledge-based library of low molecular weight compounds against the proline biosynthetic enzyme 1-pyrroline-5-carboxylate 1 (PYCR1). Protein Sci. 33, e5072
Fram, B., Su, Y., Truebridge, I., Riesselman, A. J., Ingraham, J. B., Passera, A., Napier, E., Thadani, N. N., Lim, S., Roberts, K., Kaur, G., Stiffler, M. A., Marks, D. S., Bahl, C. D., Khan, A. R., Sander, C., and Gauthier, N. P. (2024) Simultaneous enhancement of multiple functional properties using evolution-informed protein design. Nat Commun. 15, 5141
Beyett, T. S., Rana, J. K., Schaeffner, I. K., Heppner, D. E., and Eck, M. J. (2024) Structural Analysis of the Macrocyclic Inhibitor BI-4020 Binding to EGFR Kinase. ChemMedChem. 19, e202300343
Richardson, B. C., Turlington, Z. R., de Macedo, S. Vaz Ferrei, Phillips, S. K., Perry, K., Brancato, S. G., Cooke, E. W., Gwilt, J. R., Dasovich, M. A., Roering, A. J., Rossi, F. M., Snider, M. J., French, J. B., and Hicks, K. A. (2024) Structural and Functional Characterization of a Novel Class A Flavin Monooxygenase from . Biochemistry. 63, 2506-2516
Das, N. Krishna, Vogt, J., Patel, A., Banna, H. Al, and Koirala, D. (2024) Structural basis for a highly conserved RNA-mediated enteroviral genome replication. Nucleic Acids Res. 10.1093/nar/gkae627
Aguilar, E. N., Sagar, S., Murray, B. R., Rajesh, C., Lei, E. K., Michaud, S. A., Goodlett, D. R., Caffrey, T. C., Grandgenett, P. M., Swanson, B., Brooks, T. M., Black, A. R., van Faassen, H., Hussack, G., Henry, K. A., Hollingsworth, M. A., Brooks, C. L., and Radhakrishnan, P. (2024) Structural Basis for Multivalent MUC16 Recognition and Robust Anti-Pancreatic Cancer Activity of Humanized Antibody AR9.6. Mol Cancer Ther. 23, 836-853
Aguilar, E. N., Sagar, S., Murray, B. R., Rajesh, C., Lei, E. K., Michaud, S. A., Goodlett, D. R., Caffrey, T. C., Grandgenett, P. M., Swanson, B., Brooks, T. M., Black, A. R., van Faassen, H., Hussack, G., Henry, K. A., Hollingsworth, M. A., Brooks, C. L., and Radhakrishnan, P. (2024) Structural Basis for Multivalent MUC16 Recognition and Robust Anti-Pancreatic Cancer Activity of Humanized Antibody AR9.6. Mol Cancer Ther. 23, 836-853
Aguilar, E. N., Sagar, S., Murray, B. R., Rajesh, C., Lei, E. K., Michaud, S. A., Goodlett, D. R., Caffrey, T. C., Grandgenett, P. M., Swanson, B., Brooks, T. M., Black, A. R., van Faassen, H., Hussack, G., Henry, K. A., Hollingsworth, M. A., Brooks, C. L., and Radhakrishnan, P. (2024) Structural Basis for Multivalent MUC16 Recognition and Robust Anti-Pancreatic Cancer Activity of Humanized Antibody AR9.6. Mol Cancer Ther. 23, 836-853
Aleksandrova, E. V., J Y Wu, K., Tresco, B. I. C., Syroegin, E. A., Killeavy, E. E., Balasanyants, S. M., Svetlov, M. S., Gregory, S. T., Atkinson, G. C., Myers, A. G., and Polikanov, Y. S. (2024) Structural basis of Cfr-mediated antimicrobial resistance and mechanisms to evade it. Nat Chem Biol. 20, 867-876
Shi, K., Bagchi, S., Bickel, J., Esfahani, S. H., Yin, L., Cheng, T., Karamyan, V. T., and Aihara, H. (2024) Structural basis of divergent substrate recognition and inhibition of human neurolysin. Sci Rep. 14, 18420
Shi, K., Bagchi, S., Bickel, J., Esfahani, S. H., Yin, L., Cheng, T., Karamyan, V. T., and Aihara, H. (2024) Structural basis of divergent substrate recognition and inhibition of human neurolysin. Sci Rep. 14, 18420
Cao, R., Gozlan, O., Airich, A., Tveriakhina, L., Zhou, H., Jiang, H., Cole, P. A., Aster, J. C., Klein, T., Sprinzak, D., and Blacklow, S. C. (2024) Structural requirements for activity of Mind bomb1 in Notch signaling. Structure. 32, 1667-1676.e5
Ojha, M., Vogt, J., Das, N. Krishna, Redmond, E., Singh, K., Banna, H. Al, Sadat, T., and Koirala, D. (2024) Structure of saguaro cactus virus 3' translational enhancer mimics 5' cap for eIF4E binding. Proc Natl Acad Sci U S A. 121, e2313677121
Gilleran, J. A., Ashraf, K., Delvillar, M., Eck, T., Fondekar, R., Miller, E. B., Hutchinson, A., Dong, A., Seitova, A., De Souza, M. Laureano, Augeri, D., Halabelian, L., Siekierka, J., Rotella, D. P., Gordon, J., Childers, W. E., Grier, M. C., Staker, B. L., Roberge, J. Y., and Bhanot, P. (2024) Structure-Activity Relationship of a Pyrrole Based Series of PfPKG Inhibitors as Anti-Malarials. J Med Chem. 67, 3467-3503
Radakovic, A., Lewicka, A., Todisco, M., Aitken, H. R. M., Weiss, Z., Kim, S., Bannan, A., Piccirilli, J. A., and Szostak, J. W. (2024) Structure-guided aminoacylation and assembly of chimeric RNAs. bioRxiv. 10.1101/2024.03.02.583109
Banayan, N. E., Loughlin, B. J., Singh, S., Forouhar, F., Lu, G., Wong, K. - H., Neky, M., Hunt, H. S., Bateman, L. B., Tamez, A., Handelman, S. K., W Price, N., and Hunt, J. F. (2024) Systematic enhancement of protein crystallization efficiency by bulk lysine-to-arginine (KR) substitution. Protein Sci. 33, e4898
Banayan, N. E., Loughlin, B. J., Singh, S., Forouhar, F., Lu, G., Wong, K. - H., Neky, M., Hunt, H. S., Bateman, L. B., Tamez, A., Handelman, S. K., W Price, N., and Hunt, J. F. (2024) Systematic enhancement of protein crystallization efficiency by bulk lysine-to-arginine (KR) substitution. Protein Sci. 33, e4898
Li, Z., Lu, W., Beyett, T. S., Ficarro, S. B., Jiang, J., Tse, J., Kim, A. Yong- Ju, Marto, J. A., Che, J., Jänne, P. A., Eck, M. J., Zhang, T., and Gray, N. S. (2024) ZNL0325, a Pyrazolopyrimidine-Based Covalent Probe, Demonstrates an Alternative Binding Mode for Kinases. J Med Chem. 67, 2837-2848
2023
Li, Z., Wang, S., Nattermann, U., Bera, A. K., Borst, A. J., Yaman, M. Y., Bick, M. J., Yang, E. C., Sheffler, W., Lee, B., Seifert, S., Hura, G. L., Nguyen, H., Kang, A., Dalal, R., Lubner, J. M., Hsia, Y., Haddox, H., Courbet, A., Dowling, Q., Miranda, M., Favor, A., Etemadi, A., Edman, N. I., Yang, W., Weidle, C., Sankaran, B., Negahdari, B., Ross, M. B., Ginger, D. S., and Baker, D. (2023) Accurate computational design of three-dimensional protein crystals. Nat Mater. 10.1038/s41563-023-01683-1
Li, Z., Wang, S., Nattermann, U., Bera, A. K., Borst, A. J., Yaman, M. Y., Bick, M. J., Yang, E. C., Sheffler, W., Lee, B., Seifert, S., Hura, G. L., Nguyen, H., Kang, A., Dalal, R., Lubner, J. M., Hsia, Y., Haddox, H., Courbet, A., Dowling, Q., Miranda, M., Favor, A., Etemadi, A., Edman, N. I., Yang, W., Weidle, C., Sankaran, B., Negahdari, B., Ross, M. B., Ginger, D. S., and Baker, D. (2023) Accurate computational design of three-dimensional protein crystals. Nat Mater. 10.1038/s41563-023-01683-1

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