Publications

Found 1151 results
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2024
Ma, X., Li, J., Liu, N., Banerjee, S., Hu, X., Wang, X., Dong, J., Liu, K., Yang, C., and Dong, Z. (2024) Insights into the distinct membrane targeting mechanisms of WDR91 family proteins. Structure. 32, 2287-2300.e4
Zhang, Z., Fu, J., Rack, J. Gregor Mat, Li, C., Voorneveld, J., Filippov, D. V., Ahel, I., Luo, Z. - Q., and Das, C. (2024) Legionella metaeffector MavL reverses ubiquitin ADP-ribosylation via a conserved arginine-specific macrodomain. Nat Commun. 15, 2452
Münzker, L., Kimani, S. W., Fowkes, M. M., Dong, A., Zheng, H., Li, Y., Dasovich, M., Zak, K. M., Leung, A. K. L., Elkins, J. M., Kessler, D., Arrowsmith, C. H., Halabelian, L., and Böttcher, J. (2024) A ligand discovery toolbox for the WWE domain family of human E3 ligases. Commun Biol. 7, 901
Münzker, L., Kimani, S. W., Fowkes, M. M., Dong, A., Zheng, H., Li, Y., Dasovich, M., Zak, K. M., Leung, A. K. L., Elkins, J. M., Kessler, D., Arrowsmith, C. H., Halabelian, L., and Böttcher, J. (2024) A ligand discovery toolbox for the WWE domain family of human E3 ligases. Commun Biol. 7, 901
Wittlinger, F., Ogboo, B. C., Shevchenko, E., Damghani, T., Pham, C. D., Schaeffner, I. K., Oligny, B. T., Chitnis, S. P., Beyett, T. S., Rasch, A., Buckley, B., Urul, D. A., Shaurova, T., May, E. W., Schaefer, E. M., Eck, M. J., Hershberger, P. A., Poso, A., Laufer, S. A., and Heppner, D. E. (2024) Linking ATP and allosteric sites to achieve superadditive binding with bivalent EGFR kinase inhibitors. Commun Chem. 7, 38
Gitlin, A. D., Maltzman, A., Kanno, Y., Heger, K., Reja, R., Schubert, A. F., Wierciszewski, L. J., Pantua, H., Kapadia, S. B., Harris, S. F., Webster, J. D., Newton, K., and Dixit, V. M. (2024) N4BP1 coordinates ubiquitin-dependent crosstalk within the IκB kinase family to limit Toll-like receptor signaling and inflammation.. Immunity. 57, 973-986.e7
Kilgas, S., Syed, A., Toolan-Kerr, P., Swift, M. L., Roychoudhury, S., Sarkar, A., Wilkins, S., Quigley, M., Poetsch, A. R., Botuyan, M. Victoria, Cui, G., Mer, G., Ule, J., Drané, P., and Chowdhury, D. (2024) NEAT1 modulates the TIRR/53BP1 complex to maintain genome integrity. Nat Commun. 15, 8438
Gama, F. H. de Souza, Dutra, L. A., Hawgood, M., Reis, C. Vinícius, Serafim, R. A. M., Ferreira, M. A., Teodoro, B. V. M., Takarada, J. Emi, Santiago, A. S., Balourdas, D. - I., Nilsson, A. - S., Urien, B., Almeida, V. M., Gileadi, C., Ramos, P. Z., Salmazo, A., Vasconcelos, S. N. S., Cunha, M. R., Mueller, S., Knapp, S., Massirer, K. B., Elkins, J. M., Gileadi, O., Mascarello, A., Lemmens, B. B. L. G., Guimarães, C. R. W., Azevedo, H., and Couñago, R. M. (2024) Novel Dihydropteridinone Derivatives As Potent Inhibitors of the Understudied Human Kinases Vaccinia-Related Kinase 1 and Casein Kinase 1δ/ε.. J Med Chem. 67, 8609-8629
Wang, H., Cheng, C., Dal Santo, J. L., Shen, C. - H., Bylund, T., Henry, A. R., Howe, C. A., Hwang, J., Morano, N. C., Morris, D. J., Pletnev, S., Roark, R. S., Zhou, T., Hansen, B. T., Hoyt, F. H., Johnston, T. S., Wang, S., Zhang, B., Ambrozak, D. R., Becker, J. E., Bender, M. F., Changela, A., Chaudhary, R., Corcoran, M., Corrigan, A. R., Foulds, K. E., Guo, Y., Lee, M., Li, Y., Lin, B. C., Liu, T., Louder, M. K., Mandolesi, M., Mason, R. D., McKee, K., Nair, V., O'Dell, S., Olia, A. S., Ou, L., Pegu, A., Raju, N., Rawi, R., Roberts-Torres, J., Sarfo, E. K., Sastry, M., Schaub, A. J., Schmidt, S. D., Schramm, C. A., Schwartz, C. L., Smith, S. C., Stephens, T., Stuckey, J., Teng, I. - T., Todd, J. - P., Tsybovsky, Y., Van Wazer, D. J., Wang, S., Doria-Rose, N. A., Fischer, E. R., Georgiev, I. S., Hedestam, G. B. Karlsson, Sheng, Z., Woodward, R. A., Douek, D. C., Koup, R. A., Pierson, T. C., Shapiro, L., Shaw, G. M., Mascola, J. R., and Kwong, P. D. (2024) Potent and broad HIV-1 neutralization in fusion peptide-primed SHIV-infected macaques. Cell. 187, 7214-7231.e23
Wang, H., Cheng, C., Dal Santo, J. L., Shen, C. - H., Bylund, T., Henry, A. R., Howe, C. A., Hwang, J., Morano, N. C., Morris, D. J., Pletnev, S., Roark, R. S., Zhou, T., Hansen, B. T., Hoyt, F. H., Johnston, T. S., Wang, S., Zhang, B., Ambrozak, D. R., Becker, J. E., Bender, M. F., Changela, A., Chaudhary, R., Corcoran, M., Corrigan, A. R., Foulds, K. E., Guo, Y., Lee, M., Li, Y., Lin, B. C., Liu, T., Louder, M. K., Mandolesi, M., Mason, R. D., McKee, K., Nair, V., O'Dell, S., Olia, A. S., Ou, L., Pegu, A., Raju, N., Rawi, R., Roberts-Torres, J., Sarfo, E. K., Sastry, M., Schaub, A. J., Schmidt, S. D., Schramm, C. A., Schwartz, C. L., Smith, S. C., Stephens, T., Stuckey, J., Teng, I. - T., Todd, J. - P., Tsybovsky, Y., Van Wazer, D. J., Wang, S., Doria-Rose, N. A., Fischer, E. R., Georgiev, I. S., Hedestam, G. B. Karlsson, Sheng, Z., Woodward, R. A., Douek, D. C., Koup, R. A., Pierson, T. C., Shapiro, L., Shaw, G. M., Mascola, J. R., and Kwong, P. D. (2024) Potent and broad HIV-1 neutralization in fusion peptide-primed SHIV-infected macaques. Cell. 187, 7214-7231.e23
Wang, H., Cheng, C., Dal Santo, J. L., Shen, C. - H., Bylund, T., Henry, A. R., Howe, C. A., Hwang, J., Morano, N. C., Morris, D. J., Pletnev, S., Roark, R. S., Zhou, T., Hansen, B. T., Hoyt, F. H., Johnston, T. S., Wang, S., Zhang, B., Ambrozak, D. R., Becker, J. E., Bender, M. F., Changela, A., Chaudhary, R., Corcoran, M., Corrigan, A. R., Foulds, K. E., Guo, Y., Lee, M., Li, Y., Lin, B. C., Liu, T., Louder, M. K., Mandolesi, M., Mason, R. D., McKee, K., Nair, V., O'Dell, S., Olia, A. S., Ou, L., Pegu, A., Raju, N., Rawi, R., Roberts-Torres, J., Sarfo, E. K., Sastry, M., Schaub, A. J., Schmidt, S. D., Schramm, C. A., Schwartz, C. L., Smith, S. C., Stephens, T., Stuckey, J., Teng, I. - T., Todd, J. - P., Tsybovsky, Y., Van Wazer, D. J., Wang, S., Doria-Rose, N. A., Fischer, E. R., Georgiev, I. S., Hedestam, G. B. Karlsson, Sheng, Z., Woodward, R. A., Douek, D. C., Koup, R. A., Pierson, T. C., Shapiro, L., Shaw, G. M., Mascola, J. R., and Kwong, P. D. (2024) Potent and broad HIV-1 neutralization in fusion peptide-primed SHIV-infected macaques. Cell. 187, 7214-7231.e23
Coco, L. B., Toci, E. M., Chen, P. Yang- Ting, Drennan, C. L., and Meyers, C. L. Freel (2024) Potent Inhibition of DXP Synthase by a -Diaryl Bisubstrate Analog. ACS Infect Dis. 10, 1312-1326
Scott, D. C., Dharuman, S., Griffith, E., Chai, S. C., Ronnebaum, J., King, M. T., Tangallapally, R., Lee, C., Gee, C. T., Yang, L., Li, Y., Loudon, V. C., Lee, H. Won, Ochoada, J., Miller, D. J., Jayasinghe, T., Paulo, J. A., Elledge, S. J., J Harper, W., Chen, T., Lee, R. E., and Schulman, B. A. (2024) Principles of paralog-specific targeted protein degradation engaging the C-degron E3 KLHDC2. Nat Commun. 15, 8829
Hsiao, Y. - C., Wallweber, H. Ackerly, Alberstein, R. G., Lin, Z., Du, C., Etxeberria, A., Aung, T., Shang, Y., Seshasayee, D., Seeger, F., Watkins, A. M., Hansen, D. V., Bohlen, C. J., Hsu, P. L., and Hötzel, I. (2024) Rapid affinity optimization of an anti-TREM2 clinical lead antibody by cross-lineage immune repertoire mining. Nat Commun. 15, 8382
Aziz, F., Reddy, K., Vega, V. Fernandez, Dey, R., Hicks, K. A., Rao, S., Jordan, L. Ortiz, Smith, E., Shumate, J., Scampavia, L., Carpino, N., Spicer, T. P., and French, J. B. (2024) Rebamipide and Derivatives are Potent, Selective Inhibitors of Histidine Phosphatase Activity of the Suppressor of T Cell Receptor Signaling Proteins. J Med Chem. 67, 1949-1960
Adak, S., Ye, N., Calderone, L. A., Duan, M., Lubeck, W., Schäfer, R. J. B., Lukowski, A. L., Houk, K. N., Pandelia, M. - E., Drennan, C. L., and Moore, B. S. (2024) A single diiron enzyme catalyses the oxidative rearrangement of tryptophan to indole nitrile. Nat Chem. 16, 1989-1998
Adak, S., Ye, N., Calderone, L. A., Duan, M., Lubeck, W., Schäfer, R. J. B., Lukowski, A. L., Houk, K. N., Pandelia, M. - E., Drennan, C. L., and Moore, B. S. (2024) A single diiron enzyme catalyses the oxidative rearrangement of tryptophan to indole nitrile. Nat Chem. 16, 1989-1998
Mills, K. B., Maciag, J. J., Wang, C., Crawford, J. A., Enroth, T. J., Keim, K. C., Dufrêne, Y. F., D Robinson, A., Fey, P. D., Herr, A. B., and Horswill, A. R. (2024) Staphylococcus aureus skin colonization is mediated by SasG lectin variation. Cell Rep. 43, 114022
Richardson, B. C., Turlington, Z. R., de Macedo, S. Vaz Ferrei, Phillips, S. K., Perry, K., Brancato, S. G., Cooke, E. W., Gwilt, J. R., Dasovich, M. A., Roering, A. J., Rossi, F. M., Snider, M. J., French, J. B., and Hicks, K. A. (2024) Structural and Functional Characterization of a Novel Class A Flavin Monooxygenase from . Biochemistry. 63, 2506-2516
Richardson, B. C., Turlington, Z. R., de Macedo, S. Vaz Ferrei, Phillips, S. K., Perry, K., Brancato, S. G., Cooke, E. W., Gwilt, J. R., Dasovich, M. A., Roering, A. J., Rossi, F. M., Snider, M. J., French, J. B., and Hicks, K. A. (2024) Structural and Functional Characterization of a Novel Class A Flavin Monooxygenase from . Biochemistry. 63, 2506-2516
Das, N. Krishna, Vogt, J., Patel, A., Banna, H. Al, and Koirala, D. (2024) Structural basis for a highly conserved RNA-mediated enteroviral genome replication. Nucleic Acids Res. 10.1093/nar/gkae627
Zhang, Z., Yan, Y., Pang, J., Dai, L., Zhang, Q., and Yu, E. W. (2024) Structural basis of DNA recognition of the CosR regulator. mBio. 15, e0343023
Gonzalez, R., Soule, J., Phan, N., Wicht, D. K., and Dowling, D. P. (2024) Structural, biophysical, and biochemical insights into C-S bond cleavage by dimethylsulfone monooxygenase. Proc Natl Acad Sci U S A. 121, e2401858121
Viennet, T., Yin, M., Jayaraj, A., Kim, W., Sun, Z. - Y. J., Fujiwara, Y., Zhang, K., Seruggia, D., Seo, H. - S., Dhe-Paganon, S., Orkin, S. H., and Arthanari, H. (2024) Structural insights into the DNA-binding mechanism of BCL11A: The integral role of ZnF6. Structure. 32, 2276-2286.e4
Viennet, T., Yin, M., Jayaraj, A., Kim, W., Sun, Z. - Y. J., Fujiwara, Y., Zhang, K., Seruggia, D., Seo, H. - S., Dhe-Paganon, S., Orkin, S. H., and Arthanari, H. (2024) Structural Insights into the DNA-Binding Mechanism of BCL11A: The Integral Role of ZnF6. bioRxiv. 10.1101/2024.01.17.576058

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