Publications

Found 1421 results
Filters: First Letter Of Last Name is K  [Clear All Filters]
2026
Bachochin, M. J., McGuire, K. L., Cook, B. D., Ye, Q., Silletti, S., Corbett, K. D., Komives, E. A., and Herzik, M. A. (2026) An allosteric network governs Tom70 conformational dynamics to coordinate mitochondrial import. Structure. 34, 273-283.e6
Volynkina, I. A., Bortyazh, M. O., Chen, C. - W., Tereshchenkov, A. G., Karakchieva, A. O., Lukianov, D. A., Komarova, E. S., Tupikin, A. E., Skvortsov, D. A., Tevyashova, A. N., Tikhomirov, A. S., Tashlitsky, V. N., Kabilov, M. R., Shchekotikhin, A. E., Dontsova, O. A., Polikanov, Y. S., and Sergiev, P. V. (2026) Benzoxaborole-modified azithromycins inhibit translation without inducing expression. Antimicrob Agents Chemother. 10.1128/aac.01539-25
Volynkina, I. A., Bortyazh, M. O., Chen, C. - W., Tereshchenkov, A. G., Karakchieva, A. O., Lukianov, D. A., Komarova, E. S., Tupikin, A. E., Skvortsov, D. A., Tevyashova, A. N., Tikhomirov, A. S., Tashlitsky, V. N., Kabilov, M. R., Shchekotikhin, A. E., Dontsova, O. A., Polikanov, Y. S., and Sergiev, P. V. (2026) Benzoxaborole-modified azithromycins inhibit translation without inducing expression. Antimicrob Agents Chemother. 10.1128/aac.01539-25
Volynkina, I. A., Bortyazh, M. O., Chen, C. - W., Tereshchenkov, A. G., Karakchieva, A. O., Lukianov, D. A., Komarova, E. S., Tupikin, A. E., Skvortsov, D. A., Tevyashova, A. N., Tikhomirov, A. S., Tashlitsky, V. N., Kabilov, M. R., Shchekotikhin, A. E., Dontsova, O. A., Polikanov, Y. S., and Sergiev, P. V. (2026) Benzoxaborole-modified azithromycins inhibit translation without inducing expression. Antimicrob Agents Chemother. 10.1128/aac.01539-25
Kim, D., Woodbury, S. M., Ahern, W., Tischer, D., Kang, A., Joyce, E., Bera, A. K., Hanikel, N., Salike, S., Krishna, R., Yim, J., Pellock, S. J., Lauko, A., Kalvet, I., Hilvert, D., and Baker, D. (2026) Computational design of metallohydrolases. Nature. 649, 246-253
Kim, D., Woodbury, S. M., Ahern, W., Tischer, D., Kang, A., Joyce, E., Bera, A. K., Hanikel, N., Salike, S., Krishna, R., Yim, J., Pellock, S. J., Lauko, A., Kalvet, I., Hilvert, D., and Baker, D. (2026) Computational design of metallohydrolases. Nature. 649, 246-253
Kim, D., Woodbury, S. M., Ahern, W., Tischer, D., Kang, A., Joyce, E., Bera, A. K., Hanikel, N., Salike, S., Krishna, R., Yim, J., Pellock, S. J., Lauko, A., Kalvet, I., Hilvert, D., and Baker, D. (2026) Computational design of metallohydrolases. Nature. 649, 246-253
Kim, D., Woodbury, S. M., Ahern, W., Tischer, D., Kang, A., Joyce, E., Bera, A. K., Hanikel, N., Salike, S., Krishna, R., Yim, J., Pellock, S. J., Lauko, A., Kalvet, I., Hilvert, D., and Baker, D. (2026) Computational design of metallohydrolases. Nature. 649, 246-253
Bubenik, M., Mader, P., Orlicky, S., Perryman, A. L., Hamel, M., Godbout, C., Falgueyret, J. - P., Kurinov, I., Wong, C., Gingras, A. Claude, Mamane, Y., Zinda, M., Morris, S. J., Gallant, M., Sfeir, A., W Black, C., Durocher, D., Zimmermann, M., and Sicheri, F. (2026) Design of a Targeted Covalent Probe to Interrogate the DNA Polymerase Activity of Polθ.. ACS Med Chem Lett. 17, 433-440
Smil, D., Liu, Y., Xin, T., Kiyota, T., Aman, A., Grouleff, J., Hoffer, L., Joshi, D. C., Inanlou, M. R., Song, S., Mao, D. Y. L., Ogunjimi, A. A., Pau, V., Chini, F. D., Kurinov, I., Zhang, Y., Nguyen, A. Thu, Wrana, J. L., Sicheri, F., Attisano, L., Uehling, D., Al-awar, R., and Isaac, M. B. (2026) Discovery and development of potent and selective dual NUAK/MARK inhibitors as Hippo pathway modulators for the treatment of cancer. Eur J Med Chem. 311, 118798
Smil, D., Liu, Y., Xin, T., Kiyota, T., Aman, A., Grouleff, J., Hoffer, L., Joshi, D. C., Inanlou, M. R., Song, S., Mao, D. Y. L., Ogunjimi, A. A., Pau, V., Chini, F. D., Kurinov, I., Zhang, Y., Nguyen, A. Thu, Wrana, J. L., Sicheri, F., Attisano, L., Uehling, D., Al-awar, R., and Isaac, M. B. (2026) Discovery and development of potent and selective dual NUAK/MARK inhibitors as Hippo pathway modulators for the treatment of cancer. Eur J Med Chem. 311, 118798
Chen, H., Dutta, R. Prasad, Li, Z., Zhong, Y., Ma, A., Park, K. - S., Kottur, J., Park, A., Babault, N., Wang, K., Wang, D., Xiong, Y., H Kaniskan, Ü., Luo, M., Parekh, S., and Jin, J. (2026) Discovery of a Potent, Selective, and In Vivo Efficacious Covalent Inhibitor for Lysine Methyltransferase SETD8. J Med Chem. 69, 4255-4269
Chen, H., Dutta, R. Prasad, Li, Z., Zhong, Y., Ma, A., Park, K. - S., Kottur, J., Park, A., Babault, N., Wang, K., Wang, D., Xiong, Y., H Kaniskan, Ü., Luo, M., Parekh, S., and Jin, J. (2026) Discovery of a Potent, Selective, and In Vivo Efficacious Covalent Inhibitor for Lysine Methyltransferase SETD8. J Med Chem. 69, 4255-4269
Appleby, M. V., Kepa, M. W., Winter, G., McAuley, K. E., and Beale, J. H. (2026) Modelling of radiation damage and beam-induced heating of room-temperature samples at extremely high flux MX beamlines. IUCrJ. 10.1107/S2052252525011224
Yamaguchi, S., Fernandez, S. G., Wassarman, D. R., Lüders, M., Schwede, F., and Kranzusch, P. J. (2026) Nucleotide signals coordinate activation and inhibition of bacterial immunity. Nature. 652, 978-985
Lee, G. Rie, Pellock, S. J., Norn, C., Tischer, D., Dauparas, J., Anishchenko, I., Mercer, J. A. M., Kang, A., Bera, A. K., Nguyen, H., Brackenbrough, E., Sankaran, B., Goreshnik, I., Vafeados, D., Roullier, N., Han, H. L., Coventry, B., Haddox, H. K., Liu, D. R., Yeh, A. Hsien- Wei, and Baker, D. (2026) Small-molecule binding and sensing with a designed protein family. Nat Commun. 10.1038/s41467-026-70953-8
Bhuket, P. Ratnatilak, Eastwood, J. R. B., Qin, Z., Kessler, J. L., Li, Y., Katz, D., Whitby, F. G., Hill, C. P., Kirshenbaum, K., and S Yu, M. (2026) Structural and Positional Effects of Peptoid Residues on Triple Helix Stability. Biomacromolecules. 10.1021/acs.biomac.5c02232
Bhuket, P. Ratnatilak, Eastwood, J. R. B., Qin, Z., Kessler, J. L., Li, Y., Katz, D., Whitby, F. G., Hill, C. P., Kirshenbaum, K., and S Yu, M. (2026) Structural and Positional Effects of Peptoid Residues on Triple Helix Stability. Biomacromolecules. 10.1021/acs.biomac.5c02232
Bhuket, P. Ratnatilak, Eastwood, J. R. B., Qin, Z., Kessler, J. L., Li, Y., Katz, D., Whitby, F. G., Hill, C. P., Kirshenbaum, K., and S Yu, M. (2026) Structural and Positional Effects of Peptoid Residues on Triple Helix Stability. Biomacromolecules. 10.1021/acs.biomac.5c02232
Adams, J. J., Blazer, L. L., Chung, J., Karimi, M., Davidson, T., Blair, B., Waddle, C., Hokanson, C. A., Bruce, H. A., Singer, A. U., Tombak, E. - M., Gildemann, K., Tamberg, N., Kiiver, K., Ustav, M., Ma, Y., Colombo, L., Huang, L. Jun- Shen, Michnick, S. W., Moe, O. W., and Sidhu, S. S. (2026) Tetravalent antibodies are more potent and efficacious erythropoiesis-stimulating agents than erythropoietin in vivo. Protein Sci. 35, e70462
Adams, J. J., Blazer, L. L., Chung, J., Karimi, M., Davidson, T., Blair, B., Waddle, C., Hokanson, C. A., Bruce, H. A., Singer, A. U., Tombak, E. - M., Gildemann, K., Tamberg, N., Kiiver, K., Ustav, M., Ma, Y., Colombo, L., Huang, L. Jun- Shen, Michnick, S. W., Moe, O. W., and Sidhu, S. S. (2026) Tetravalent antibodies are more potent and efficacious erythropoiesis-stimulating agents than erythropoietin in vivo. Protein Sci. 35, e70462
2025
Primi, M. C., Tavares, M. T., Hatcher, J. M., Kang, H., Kresina, T. A. C., Chakraborty, S., Leroy, E., Schmoker, A. M., Jeon, H., Weisberg, E. L., Akatsu, T., Griffin, J. D., Scott, D. A., and Eck, M. J. (2025) Allosteric inhibition of JAK2 with lysine-reactive compounds that bind the pseudokinase domain. Eur J Med Chem. 302, 118274
Primi, M. C., Tavares, M. T., Hatcher, J. M., Kang, H., Kresina, T. A. C., Chakraborty, S., Leroy, E., Schmoker, A. M., Jeon, H., Weisberg, E. L., Akatsu, T., Griffin, J. D., Scott, D. A., and Eck, M. J. (2025) Allosteric inhibition of JAK2 with lysine-reactive compounds that bind the pseudokinase domain. Eur J Med Chem. 302, 118274
Nuthanakanti, A., Korn, M., Levenson-Palmer, R., Wu, Y., Babu, N. Rajesh, Huang, X., Banh, R. S., Belasco, J. G., and Serganov, A. (2025) ApaH decaps NpN-capped RNAs in two alternative orientations. Nat Chem Biol. 10.1038/s41589-025-01991-4
Adams, J. J., Blazer, L. L., Chung, J., Karimi, M., Davidson, T., Bruce, H. A., Singer, A. U., Yang, N., Cardarelli, L., Pot, I., Colombo, L., Huang, L. Jun- Shen, Ma, Y., Michnick, S. W., Moe, O. W., and Sidhu, S. S. (2025) An asymmetric tetrabody is a potent and efficacious agonist of the erythropoietin receptor in vitro and in vivo. Protein Sci. 34, e70292

Pages