Publications
Structure of VanS from vancomycin-resistant enterococci: A sensor kinase with weak ATP binding.. J Biol Chem. 299, 103001
(2023) Structure-based design of nanobodies that inhibit seeding of Alzheimer's patient-extracted tau fibrils. Proc Natl Acad Sci U S A. 120, e2300258120
(2023) Structure-based design of nanobodies that inhibit seeding of Alzheimer's patient-extracted tau fibrils. Proc Natl Acad Sci U S A. 120, e2300258120
(2023) Structure-based design of nanobodies that inhibit seeding of Alzheimer's patient-extracted tau fibrils. Proc Natl Acad Sci U S A. 120, e2300258120
(2023) Targeting the Spike Receptor Binding Domain Class V Cryptic Epitope by an Antibody with Pan-Sarbecovirus Activity. J Virol. 97, e0159622
(2023) (2023) TRIM56 coiled-coil domain structure provides insights into its E3 ligase functions. Comput Struct Biotechnol J. 21, 2801-2808
(2023) TRIM56 coiled-coil domain structure provides insights into its E3 ligase functions. Comput Struct Biotechnol J. 21, 2801-2808
(2023) Tuning the Metabolic Stability of Visual Cycle Modulators through Modification of an RPE65 Recognition Motif. J Med Chem. 66, 8140-8158
(2023) Understanding ATP Binding to DosS Catalytic Domain with a Short ATP-Lid. Biochemistry. 62, 3283-3292
(2023) Understanding ATP binding to DosS catalytic domain with a short ATP-lid. bioRxiv. 10.1101/2023.05.29.542785
(2023) X-ray Crystallographic Study of Preferred Spacing by the NF-κB p50 Homodimer on κB DNA.. Biomolecules. 10.3390/biom13091310
(2023) (2023) (2023) (2023) (2023) An antibiotic preorganized for ribosomal binding overcomes antimicrobial resistance. Science. 383, 721-726
(2024) An antibiotic preorganized for ribosomal binding overcomes antimicrobial resistance. Science. 383, 721-726
(2024) Antigen-binding fragments with improved crystal lattice packing and enhanced conformational flexibility at the elbow region as crystallization chaperones. Protein Sci. 33, e5081
(2024) Berberine analog of chloramphenicol exhibits a distinct mode of action and unveils ribosome plasticity. Structure. 10.1016/j.str.2024.06.013
(2024) Binding and sensing diverse small molecules using shape-complementary pseudocycles. Science. 385, 276-282
(2024) Binding and sensing diverse small molecules using shape-complementary pseudocycles. Science. 385, 276-282
(2024) Binding and sensing diverse small molecules using shape-complementary pseudocycles. Science. 385, 276-282
(2024) A chemical probe to modulate human GID4 Pro/N-degron interactions. Nat Chem Biol. 10.1038/s41589-024-01618-0
(2024) A chemical probe to modulate human GID4 Pro/N-degron interactions. Nat Chem Biol. 10.1038/s41589-024-01618-0
(2024)